Q9I8I2 (BOK_CHICK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Bcl-2-related ovarian killer protein

Gene names

Name:

BOK

Organism

Gallus gallus (Chicken)

Taxonomic identifier

9031 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galliformes › Phasianidae › Phasianinae › Gallus

Protein attributes

Sequence length	213 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	May play a role in apoptosis.
Sequence similarities	Belongs to the Bcl-2 family.

Ontologies

Keywords
Biological process	Apoptosis
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 213	213	Bcl-2-related ovarian killer protein		PRO_0000143089
Regions
	Motif	32 – 44	13	BH4
	Motif	67 – 83	17	BH3
	Motif	113 – 132	20	BH1
	Motif	165 – 179	15	BH2

Sequences

	Sequence		Length	Mass (Da)
	Q9I8I2 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: B3AF7049F25442E3	FASTA	213	23,620
	10 20 30 40 50 60 MEVLRRSSVF AAEVMEVFDR SPTDKELVSQ AKALCRDYIN SRLIRAGVSW SKPEHNTPVP 70 80 90 100 110 120 GGKLAEVSAI LLRLGDELEY IRPNVYRNIA RQLNISLHSE TVVTDAFLAV AAQIFTAGIT 130 140 150 160 170 180 WGKVVSLYAV AAGLAVDCVR HAQPAMVHTI VDCLGEFVRK TLVTWLKRRG GWADITKCVV 190 200 210 STDPSLRSHW LVAAVCSFGH FLKAIFFVLL PER

References

[1]	"Evolutionarily conserved Bok proteins in the Bcl-2 family." Zhang H., Holzgreve W., De Geyter C. FEBS Lett. 480:311-313(2000) [PubMed: 11034351] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]	"Characterization and expression of Bok in the hen ovary." Mills E.M., Johnson A.L., Bridgham J.T. Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF275944 mRNA. Translation: AAF81282.1. AF290888 mRNA. Translation: AAG01182.1.
IPI	IPI00594286.
RefSeq	NP_990037.1. NM_204706.1.
UniGene	Gga.3811.
3D structure databases
ProteinModelPortal	Q9I8I2.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9I8I2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	395445.
KEGG	gga:395445.
Organism-specific databases
CTD	666.
Phylogenomic databases
eggNOG	veNOG08825.
GeneTree	ENSGT00510000048498.
HOGENOM	HBG445898.
HOVERGEN	HBG050709.
InParanoid	Q9I8I2.
OrthoDB	EOG476K15.
Family and domain databases
InterPro	IPR002475. Bcl2-like_apoptosis. IPR000712. Bcl2_BH. [Graphical view]
KO	K02561.
Pfam	PF00452. Bcl-2. 1 hit. [Graphical view]
PRINTS	PR01862. BCL2FAMILY.
SMART	SM00337. BCL. 1 hit. [Graphical view]
PROSITE	PS50062. BCL2_FAMILY. 1 hit. PS01080. BH1. False negative. PS01258. BH2. False negative. PS01259. BH3. False negative. PS01260. BH4_1. False negative. PS50063. BH4_2. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

BOK_CHICK

Accession

Primary (citable) accession number: Q9I8I2
Secondary accession number(s): Q9DGJ5

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 4, 2005
Last sequence update:	October 1, 2000
Last modified:	November 16, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program