Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Bcl-2-related ovarian killer protein

Gene

BOK

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May play a role in apoptosis.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Apoptosis

Names & Taxonomyi

Protein namesi
Recommended name:
Bcl-2-related ovarian killer protein2 Publications
Gene namesi
Name:BOK2 Publications
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Unplaced

Subcellular locationi

  • Membrane By similarity; Single-pass membrane protein By similarity

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei190 – 210HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001430891 – 213Bcl-2-related ovarian killer proteinAdd BLAST213

Proteomic databases

PaxDbiQ9I8I2.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000009257.

Structurei

3D structure databases

ProteinModelPortaliQ9I8I2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi32 – 44BH4Add BLAST13
Motifi67 – 83BH3Add BLAST17
Motifi113 – 132BH1Add BLAST20
Motifi165 – 179BH2Add BLAST15

Sequence similaritiesi

Belongs to the Bcl-2 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4728. Eukaryota.
ENOG41123S0. LUCA.
HOGENOMiHOG000290675.
HOVERGENiHBG050709.
InParanoidiQ9I8I2.
KOiK02561.
PhylomeDBiQ9I8I2.

Family and domain databases

InterProiIPR002475. Bcl2-like.
IPR026298. Blc2_fam.
IPR026309. BOK.
[Graphical view]
PANTHERiPTHR11256. PTHR11256. 1 hit.
PTHR11256:SF48. PTHR11256:SF48. 1 hit.
PfamiPF00452. Bcl-2. 1 hit.
[Graphical view]
PRINTSiPR01862. BCL2FAMILY.
PROSITEiPS50062. BCL2_FAMILY. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9I8I2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEVLRRSSVF AAEVMEVFDR SPTDKELVSQ AKALCRDYIN SRLIRAGVSW
60 70 80 90 100
SKPEHNTPVP GGKLAEVSAI LLRLGDELEY IRPNVYRNIA RQLNISLHSE
110 120 130 140 150
TVVTDAFLAV AAQIFTAGIT WGKVVSLYAV AAGLAVDCVR HAQPAMVHTI
160 170 180 190 200
VDCLGEFVRK TLVTWLKRRG GWADITKCVV STDPSLRSHW LVAAVCSFGH
210
FLKAIFFVLL PER
Length:213
Mass (Da):23,620
Last modified:October 1, 2000 - v1
Checksum:iB3AF7049F25442E3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF275944 mRNA. Translation: AAF81282.1.
AF290888 mRNA. Translation: AAG01182.1.
RefSeqiNP_990037.1. NM_204706.1.
UniGeneiGga.3811.

Genome annotation databases

GeneIDi395445.
KEGGigga:395445.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF275944 mRNA. Translation: AAF81282.1.
AF290888 mRNA. Translation: AAG01182.1.
RefSeqiNP_990037.1. NM_204706.1.
UniGeneiGga.3811.

3D structure databases

ProteinModelPortaliQ9I8I2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000009257.

Proteomic databases

PaxDbiQ9I8I2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi395445.
KEGGigga:395445.

Organism-specific databases

CTDi666.

Phylogenomic databases

eggNOGiKOG4728. Eukaryota.
ENOG41123S0. LUCA.
HOGENOMiHOG000290675.
HOVERGENiHBG050709.
InParanoidiQ9I8I2.
KOiK02561.
PhylomeDBiQ9I8I2.

Miscellaneous databases

PROiQ9I8I2.

Family and domain databases

InterProiIPR002475. Bcl2-like.
IPR026298. Blc2_fam.
IPR026309. BOK.
[Graphical view]
PANTHERiPTHR11256. PTHR11256. 1 hit.
PTHR11256:SF48. PTHR11256:SF48. 1 hit.
PfamiPF00452. Bcl-2. 1 hit.
[Graphical view]
PRINTSiPR01862. BCL2FAMILY.
PROSITEiPS50062. BCL2_FAMILY. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiBOK_CHICK
AccessioniPrimary (citable) accession number: Q9I8I2
Secondary accession number(s): Q9DGJ5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: October 1, 2000
Last modified: November 30, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.