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Protein

Palmitoyltransferase

Gene

Dmel\CG18810

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

  • protein-cysteine S-palmitoyltransferase activity Source: FlyBase

GO - Biological processi

  • protein palmitoylation Source: FlyBase

Keywordsi

Molecular functionAcyltransferaseUniRule annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
Name:Dmel\CG18810Imported
ORF Names:CG18810Imported, Dmel_CG18810Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0042133. CG18810.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei20 – 39HelicalUniRule annotationAdd BLAST20
Transmembranei51 – 74HelicalUniRule annotationAdd BLAST24
Transmembranei141 – 167HelicalUniRule annotationAdd BLAST27
Transmembranei205 – 226HelicalUniRule annotationAdd BLAST22

GO - Cellular componenti

  • Golgi apparatus Source: FlyBase
  • integral component of membrane Source: UniProtKB-KW

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiFBgn0042133.

Interactioni

Protein-protein interaction databases

MINTiMINT-921164.
STRINGi7227.FBpp0080916.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini96 – 220DHHCInterPro annotationAdd BLAST125

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1311. Eukaryota.
COG5273. LUCA.
GeneTreeiENSGT00850000132405.
KOiK18932.
OMAiPRSRHCR.
OrthoDBiEOG091G0RWR.

Family and domain databases

InterProiView protein in InterPro
IPR001594. Palmitoyltrfase_DHHC.
PfamiView protein in Pfam
PF01529. DHHC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9I7L7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRFRSLKNIW PKEKLEQFLF LFILCGLPAI YYVLMEIILP ELSDYWSPGY
60 70 80 90 100
VFQLLLGLFL FSNVMSNYVM CILVDPSIDP KLMKNQLVRG QHSEDWHECD
110 120 130 140 150
KCGILAPPRS RHCRKCGVCV LMRDHHCFFT GCCIGHENYR YFFYFLIYFF
160 170 180 190 200
LSCMISLTSS SIFIYVLHGG RYQLFMLTHP APNSAYFNSL IIRIIYFKLP
210 220 230 240 250
DIYELVFTLV FVLLWIGVCV ATYVAYDQWS RGYFCYDFEL QNIPFDRKLR
260 270 280 290 300
RNFKTFLGRR MKWTWISGFV PSQLDHDGFD LDPDNERVAD WCSETTIKDG
Length:300
Mass (Da):35,597
Last modified:July 5, 2004 - v2
Checksum:i7AA96CFD8DC9675D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA. Translation: AAG22448.2.
BT030752 mRNA. Translation: ABV82134.1.
RefSeqiNP_652670.2. NM_144413.3.
UniGeneiDm.17919.

Genome annotation databases

EnsemblMetazoaiFBtr0081386; FBpp0080916; FBgn0042133.
GeneIDi59171.
KEGGidme:Dmel_CG18810.
UCSCiCG18810-RA. d. melanogaster.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ9I7L7_DROME
AccessioniPrimary (citable) accession number: Q9I7L7
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: July 5, 2004
Last modified: July 5, 2017
This is version 127 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported