Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Chemotaxis protein methyltransferase 2

Gene

cheR2

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.By similarity

Catalytic activityi

S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine + protein L-glutamate methyl ester.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei85S-adenosyl-L-methionineBy similarity1
Binding sitei87S-adenosyl-L-methionineBy similarity1
Binding sitei91S-adenosyl-L-methionineBy similarity1
Binding sitei125S-adenosyl-L-methionineBy similarity1
Binding sitei150S-adenosyl-L-methionineBy similarity1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Ligandi

S-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Chemotaxis protein methyltransferase 2 (EC:2.1.1.80)
Gene namesi
Name:cheR2
Ordered Locus Names:PA0175
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA0175.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001760381 – 280Chemotaxis protein methyltransferase 2Add BLAST280

Proteomic databases

PaxDbiQ9I6V7.

Interactioni

Protein-protein interaction databases

STRINGi208964.PA0175.

Structurei

3D structure databases

ProteinModelPortaliQ9I6V7.
SMRiQ9I6V7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 280CheR-type methyltransferasePROSITE-ProRule annotationAdd BLAST271

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni208 – 209S-adenosyl-L-methionine bindingBy similarity2
Regioni226 – 227S-adenosyl-L-methionine bindingBy similarity2

Sequence similaritiesi

Contains 1 cheR-type methyltransferase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105BZU. Bacteria.
ENOG410XNMH. LUCA.
InParanoidiQ9I6V7.
KOiK00575.
OMAiFVGHAEN.
PhylomeDBiQ9I6V7.

Family and domain databases

Gene3Di1.10.155.10. 1 hit.
3.40.50.150. 1 hit.
InterProiIPR026024. Chemotaxis_MeTrfase_CheR.
IPR022642. CheR_C.
IPR000780. CheR_MeTrfase.
IPR022641. CheR_N.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PfamiPF01739. CheR. 1 hit.
PF03705. CheR_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000410. CheR. 1 hit.
PRINTSiPR00996. CHERMTFRASE.
SMARTiSM00138. MeTrc. 1 hit.
[Graphical view]
SUPFAMiSSF47757. SSF47757. 1 hit.
SSF53335. SSF53335. 1 hit.
PROSITEiPS50123. CHER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9I6V7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPTSTPSPVF GNQEFHYTRE DFQQVRERLY RLTGISLAES KAQLVYSRLS
60 70 80 90 100
RRLRLLRLGS FAEYFTHLDR EPGEQQLFVN ALTTNLTAFF RERHHFPLLA
110 120 130 140 150
DLARRQLQRH RPLRIWSAAA STGEEPYSIA ITLVEALGSF DPPVKIVASD
160 170 180 190 200
IDTGVLDCAR QGVYPLERLE QMPAPLKKRF FLRGTGPNAG KARVVEELRQ
210 220 230 240 250
LVEFRQINLL EADWSIAGEL DAIFCRNVMI YFDKPTQTRL LERMVALLRP
260 270 280
EGLFFAGHSE NFVHASHLVR SVGQTVYSPA
Length:280
Mass (Da):32,029
Last modified:March 1, 2001 - v1
Checksum:iFD2AF1491DDC57FB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG03565.1.
PIRiH83623.
RefSeqiNP_248865.1. NC_002516.2.
WP_003102222.1. NZ_ASJY01000038.1.

Genome annotation databases

EnsemblBacteriaiAAG03565; AAG03565; PA0175.
GeneIDi882282.
KEGGipae:PA0175.
PATRICi19834558. VBIPseAer58763_0181.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG03565.1.
PIRiH83623.
RefSeqiNP_248865.1. NC_002516.2.
WP_003102222.1. NZ_ASJY01000038.1.

3D structure databases

ProteinModelPortaliQ9I6V7.
SMRiQ9I6V7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi208964.PA0175.

Proteomic databases

PaxDbiQ9I6V7.

Protocols and materials databases

DNASUi882282.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG03565; AAG03565; PA0175.
GeneIDi882282.
KEGGipae:PA0175.
PATRICi19834558. VBIPseAer58763_0181.

Organism-specific databases

PseudoCAPiPA0175.

Phylogenomic databases

eggNOGiENOG4105BZU. Bacteria.
ENOG410XNMH. LUCA.
InParanoidiQ9I6V7.
KOiK00575.
OMAiFVGHAEN.
PhylomeDBiQ9I6V7.

Family and domain databases

Gene3Di1.10.155.10. 1 hit.
3.40.50.150. 1 hit.
InterProiIPR026024. Chemotaxis_MeTrfase_CheR.
IPR022642. CheR_C.
IPR000780. CheR_MeTrfase.
IPR022641. CheR_N.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PfamiPF01739. CheR. 1 hit.
PF03705. CheR_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000410. CheR. 1 hit.
PRINTSiPR00996. CHERMTFRASE.
SMARTiSM00138. MeTrc. 1 hit.
[Graphical view]
SUPFAMiSSF47757. SSF47757. 1 hit.
SSF53335. SSF53335. 1 hit.
PROSITEiPS50123. CHER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCHER2_PSEAE
AccessioniPrimary (citable) accession number: Q9I6V7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: March 1, 2001
Last modified: November 2, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.