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Q9I6V6 (Q9I6V6_PSEAE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length679 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2341Iron (heme 1 axial ligand); via tele nitrogen PDB 4HI4
Metal binding2341Iron (heme 2 axial ligand); via tele nitrogen
Binding site111Chloride 1 PDB 3LNR
Binding site1521Sulfate PDB 4I3M
Binding site1561Sulfate PDB 4I3M
Binding site2831Cyanide

Sequences

Sequence LengthMass (Da)Tools
Q9I6V6 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: 246EF0D775120272

FASTA67972,591
        10         20         30         40         50         60 
MGLFNAHAVA QQRADRIATL LQSFADGQLD TAVGEAPAPG YERLYDSLRA LQRQLREQRA 

        70         80         90        100        110        120 
ELQQVESLEA GLAEMSRQHE AGWIDQTIPA ERLEGRAARI AKGVNELVAA HIAVKMKVVS 

       130        140        150        160        170        180 
VVTAYGQGNF EPLMDRLPGK KAQITEAIDG VRERLRGAAE ATSAQLATAA YNARIKSALD 

       190        200        210        220        230        240 
NVSANVMIAD NDLNIIYMNR TVSEMLGRAE ADIRKQLPNF DAGRLMGANI DVFHKNPAHQ 

       250        260        270        280        290        300 
RHLLANLTGV HKAELNLGGR RFSLDVVPVF NDANERLGSA VQWTDRTEEH RAEQEVSQLV 

       310        320        330        340        350        360 
QAAAAGDFSK RVEEAGKEGF FLRLAKDLNS LVDTADRGLR DVSRMLGALA QGDLTQRIEA 

       370        380        390        400        410        420 
DYQGTFGQLK DFSNDTAQSL SRMLGQIREA ADTINTAASE IASGNAELSA RTEQQASSLE 

       430        440        450        460        470        480 
ETASSMEELT STVKLNAENA RQANSLAANA SEVATQGGTV VQKVVSTMSS INESARKIAD 

       490        500        510        520        530        540 
IIGVIDGIAF QTNILALNAA VEAARAGEQG RGFAVVAGEV RTLAQRSAAA AKEIKTLISD 

       550        560        570        580        590        600 
SVDKVENGNT LVAQAGQTMS DIVVAIRRVT DIMSEIAAAS AEQSTGIEEV NSAVSQMDDM 

       610        620        630        640        650        660 
TQQNAALVEE AAAAAEAMQE QAGLLNQSVA VFRLDTPPSV VQLASARPSA PRPSAPAPLA 

       670 
RSGMARASKA RKEDGWEEF 

« Hide

References

« Hide 'large scale' references
[1]"Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen."
Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P., Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M., Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y., Brody L.L., Coulter S.N., Folger K.R. expand/collapse author list , Kas A., Larbig K., Lim R.M., Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J., Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.
Nature 406:959-964(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.
[2]"Structure of concatenated HAMP domains provides a mechanism for signal transduction."
Airola M.V., Watts K.J., Bilwes A.M., Crane B.R.
Structure 18:436-448(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.64 ANGSTROMS) OF 1-172 IN COMPLEX WITH CHLORIDE.
[3]"Structural basis for oxygen sensing and signal transduction of the heme-based sensor protein Aer2 from Pseudomonas aeruginosa."
Sawai H., Sugimoto H., Shiro Y., Ishikawa H., Mizutani Y., Aono S.
Chem. Commun. (Camb.) 48:6523-6525(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) OF 173-384 IN COMPLEX WITH CYANIDE AND HEME.
[4]"Architecture of the soluble receptor Aer2 indicates an in-line mechanism for PAS and HAMP domain signaling."
Airola M.V., Huh D., Sukomon N., Widom J., Sircar R., Borbat P.P., Freed J.H., Watts K.J., Crane B.R.
J. Mol. Biol. 425:886-901(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) OF 174-289 IN COMPLEX WITH HEME.
[5]"HAMP domain conformers that propagate opposite signals in bacterial chemoreceptors."
Airola M.V., Sukomon N., Samanta D., Borbat P.P., Freed J.H., Watts K.J., Crane B.R.
PLoS Biol. 11:e1001479-e1001479(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.95 ANGSTROMS) OF 1-172 IN COMPLEX WITH SULFATE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE004091 Genomic DNA. Translation: AAG03566.1.
PIRA83624.
RefSeqNP_248866.1. NC_002516.2.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3LNRX-ray2.64A1-172[»]
3VOLX-ray2.40A173-384[»]
4HI4X-ray2.30A/B/D/G174-289[»]
4I3MX-ray1.95A1-172[»]
4I44X-ray2.88A1-172[»]
ProteinModelPortalQ9I6V6.
SMRQ9I6V6. Positions 1-157, 169-306, 334-634.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING208964.PA0176.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID882219.
KEGGpae:PA0176.
PATRIC19834560. VBIPseAer58763_0182.

Organism-specific databases

PseudoCAPPA0176.

Phylogenomic databases

KOK03406.
OMANASCSEE.
OrthoDBEOG6G4VQG.
ProtClustDBCLSK865659.

Family and domain databases

InterProIPR004090. Chemotax_Me-accpt_rcpt.
IPR003660. HAMP_linker_domain.
IPR004089. MCPsignal_dom.
IPR000014. PAS.
[Graphical view]
PfamPF00015. MCPsignal. 1 hit.
PF13188. PAS_8. 1 hit.
[Graphical view]
PRINTSPR00260. CHEMTRNSDUCR.
SMARTSM00304. HAMP. 2 hits.
SM00283. MA. 1 hit.
SM00091. PAS. 1 hit.
[Graphical view]
SUPFAMSSF55785. SSF55785. 1 hit.
PROSITEPS50111. CHEMOTAXIS_TRANSDUC_2. 1 hit.
PS50885. HAMP. 1 hit.
PS50112. PAS. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ9I6V6.

Entry information

Entry nameQ9I6V6_PSEAE
AccessionPrimary (citable) accession number: Q9I6V6
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: April 16, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)