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Protein

Probable 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase

Gene

mdcB

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in the formation of 2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase.UniRule annotation

Catalytic activityi

ATP + 3'-dephospho-CoA = 2'-(5-triphospho-alpha-D-ribosyl)-3'-dephospho-CoA + adenine.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthaseUniRule annotation (EC:2.4.2.52UniRule annotation)
Short name:
2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthaseUniRule annotation
Gene namesi
Name:mdcBUniRule annotation
Ordered Locus Names:PA0209
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA0209.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 293293Probable 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthasePRO_0000214673Add
BLAST

Proteomic databases

PaxDbiQ9I6S9.

Interactioni

Protein-protein interaction databases

STRINGi208964.PA0209.

Structurei

3D structure databases

ProteinModelPortaliQ9I6S9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CitG/MdcB family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108K6F. Bacteria.
COG1767. LUCA.
HOGENOMiHOG000258582.
InParanoidiQ9I6S9.
KOiK13930.
OMAiQSWQRPA.
PhylomeDBiQ9I6S9.

Family and domain databases

HAMAPiMF_01883. MdcB. 1 hit.
InterProiIPR002736. CitG.
IPR017555. TriPribosyl-deP-CoA_syn.
[Graphical view]
PfamiPF01874. CitG. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03132. malonate_mdcB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9I6S9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNAIANLAAT PGADLGECLA DLAVDALIDE AELSPKPALV DRRGNGAHAD
60 70 80 90 100
LHLGLMQASA LSLWPCFKEM ADAAQRHGRI DARLRGVLGQ LGRDGEAAML
110 120 130 140 150
RTTEGVNTHR GAIWALGLLV AAAALEPRRT QAGEVAARAG RIALLDDPAA
160 170 180 190 200
AIGDSHGERV RRRYGVGGAR EEARLCFPRA VRHGLPQLWR SREGGAGEQN
210 220 230 240 250
ARLDALLAIM SVLDDTCVLH RAGRVGLAAM QDGARAVLAA GGSASLAGRR
260 270 280 290
RLCELDRRLL ALNASPGGAA DLLAACLFLD RLPAVSGGWA GSL
Length:293
Mass (Da):30,534
Last modified:March 1, 2001 - v1
Checksum:iA9A085F070C680B3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG03598.1.
PIRiF83618.
RefSeqiNP_248900.1. NC_002516.2.
WP_003112667.1. NC_002516.2.

Genome annotation databases

EnsemblBacteriaiAAG03598; AAG03598; PA0209.
GeneIDi879248.
KEGGipae:PA0209.
PATRICi19834630. VBIPseAer58763_0217.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG03598.1.
PIRiF83618.
RefSeqiNP_248900.1. NC_002516.2.
WP_003112667.1. NC_002516.2.

3D structure databases

ProteinModelPortaliQ9I6S9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi208964.PA0209.

Proteomic databases

PaxDbiQ9I6S9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG03598; AAG03598; PA0209.
GeneIDi879248.
KEGGipae:PA0209.
PATRICi19834630. VBIPseAer58763_0217.

Organism-specific databases

PseudoCAPiPA0209.

Phylogenomic databases

eggNOGiENOG4108K6F. Bacteria.
COG1767. LUCA.
HOGENOMiHOG000258582.
InParanoidiQ9I6S9.
KOiK13930.
OMAiQSWQRPA.
PhylomeDBiQ9I6S9.

Family and domain databases

HAMAPiMF_01883. MdcB. 1 hit.
InterProiIPR002736. CitG.
IPR017555. TriPribosyl-deP-CoA_syn.
[Graphical view]
PfamiPF01874. CitG. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03132. malonate_mdcB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiMDCB_PSEAE
AccessioniPrimary (citable) accession number: Q9I6S9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: March 1, 2001
Last modified: September 7, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.