Q9I6A1 (Q9I6A1_PSEAE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Cysteine synthase RuleBase RU003985
EC=2.5.1.47 RuleBase RU003985

Gene names

Ordered Locus Names:

PA0399

Organism

Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)

Taxonomic identifier

208964 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	457 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	O(3)-acetyl-L-serine + H2S = L-cysteine + acetate. RuleBase RU003985
Sequence similarities	Belongs to the cysteine synthase/cystathionine beta-synthase family. RuleBase RU003985

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Cysteine biosynthesis RuleBase RU003985
Molecular function	Transferase RuleBase RU003985
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cysteine biosynthetic process from serine Inferred from electronic annotation. Source: InterPro
Molecular function	cysteine synthase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro transferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9I6A1 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 7AB5CE18D6675354	FASTA	457	49,171
	10 20 30 40 50 60 MTSDSRPAVL DLIGNTPLVR VTRFDTGPCT LYLKLESQNP GGSIKDRIGV AMIEAAERDG 70 80 90 100 110 120 RLRPGGTIVE ATAGNTGLGL ALVGRAKGYR VVLVVPDKMS TEKVLHLRAM GAEVHITRSD 130 140 150 160 170 180 VGKGHPEYYQ DVAARLAQDI PGAFFADQFN NPANPLAHEC GTGPELWAQT GHDLDAIVVG 190 200 210 220 230 240 VGSSGTLTGL TRFFQKVQPE LEMVLADPEG SIMAEYSRSG TLGTPGSWAV EGIGEDFVPA 250 260 270 280 290 300 IADLSSVRHA YSISDEESFA MARELLRVEG IPGGSSTGTL LAAALRFCRE QKEPKRVVSF 310 320 330 340 350 360 VCDTGTRYLS KIYNDQWMTD QGLLQRKHYG DLRDIIARRF EEGRVISVGP DDTLLTAFQR 370 380 390 400 410 420 MRLADVSQLP VLDDGKLVGV IDESDILLGV HADAPRFRDA VSSAMNAAPE TLAPGASLAQ 430 440 450 LQAVLDRGLV AIVADASGFH GLITRFDLLN HLRRKLA

References

[1]

"Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen." Stover C.K., Pham X.Q., Erwin A.L., Mizoguchi S.D., Warrener P., Hickey M.J., Brinkman F.S., Hufnagle W.O., Kowalik D.J., Lagrou M., Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y., Brody L.L., Coulter S.N., Folger K.R. , Kas A., Larbig K., Lim R., Smith K., Spencer D., Wong G.K., Wu Z., Paulsen I.T., Reizer J., Saier M.H., Hancock R.E., Lory S., Olson M.V. Nature 406:959-964(2000) [PubMed: 10984043] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE004091 Genomic DNA. Translation: AAG03788.1.
PIR	E83595.
RefSeq	NP_249090.1. NC_002516.2.
3D structure databases
HSSP	HSSP built from PDB template 1M54 based on UniProtKB P35520.
ProteinModelPortal	Q9I6A1.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	878291.
GenomeReviews	Gene locus PA0399 in contig AE004091_GR.
KEGG	pae:PA0399.
PATRIC	19835038. VBIPseAer58763_0420.
Organism-specific databases
PseudoCAP	PA0399.
Phylogenomic databases
HOGENOM	HBG748215.
OMA	QTEPKRV.
ProtClustDB	CLSK865834.
Enzyme and pathway databases
BioCyc	PAER208964:PA0399-MONOMER.
Family and domain databases
InterPro	IPR001216. Cys_synth_BS. IPR000644. Cysta_beta_synth_core. IPR001926. PyrdxlP-dep_enz_bsu. [Graphical view]
KO	K01697.
Pfam	PF00571. CBS. 1 hit. PF00291. PALP. 1 hit. [Graphical view]
SMART	SM00116. CBS. 1 hit. [Graphical view]
SUPFAM	SSF53686. PyrdxlP-dep_enz_bsu. 1 hit.
PROSITE	PS51371. CBS. 1 hit. PS00901. CYS_SYNTHASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9I6A1_PSEAE

Accession

Primary (citable) accession number: Q9I6A1

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2001
Last sequence update:	March 1, 2001
Last modified:	December 14, 2011
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)