SDS hydrolase SdsA1 - Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)

Preferred order of sections

Names and origin

Protein names

Submitted name:
SDS hydrolase SdsA1 EMBL AAG04129.1

Gene names

Name:	sdsA1 EMBL AAG04129.1
Ordered Locus Names:	PA0740

Organism

Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) [Reference proteome] [HAMAP] EMBL AAG04129.1

Taxonomic identifier

208964 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas ›

Protein attributes

Sequence length	658 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Ligand	Metal-binding PDB 2CFU PDB 2CFZ PDB 2CG2 PDB 2CG3 Zinc PDB 2CFU PDB 2CFZ PDB 2CG2 PDB 2CG3
Molecular function	Hydrolase EMBL AAG04129.1
Technical term	3D-structure PDB 2CFU PDB 2CFZ PDB 2CG2 PDB 2CG3 Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	hydrolase activity Inferred from electronic annotation. Source: UniProtKB-KW metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW sterol binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Sites

Metal binding

169

1

Zinc 1; via tele nitrogen PDB 2CFU PDB 2CFZ PDB 2CG2 PDB 2CG3

Metal binding

171

1

Zinc 1; via pros nitrogen PDB 2CFU PDB 2CFZ PDB 2CG2 PDB 2CG3

Metal binding

173

1

Zinc 2 PDB 2CFU PDB 2CFZ PDB 2CG2 PDB 2CG3

Metal binding

174

1

Zinc 2; via tele nitrogen PDB 2CFU PDB 2CFZ PDB 2CG2 PDB 2CG3

Metal binding

280

1

Zinc 1 PDB 2CFU PDB 2CFZ PDB 2CG2

Metal binding

299

1

Zinc 1 PDB 2CFU PDB 2CFZ PDB 2CG2 PDB 2CG3

Metal binding

299

1

Zinc 2 PDB 2CFU PDB 2CFZ PDB 2CG2 PDB 2CG3

Metal binding

344

1

Zinc 2; via tele nitrogen PDB 2CFU PDB 2CFZ PDB 2CG2 PDB 2CG3

Sequences

Sequence

Length

Mass (Da)

Tools

Q9I5I9 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: 3D29B5D2B0A2A84F
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FASTA

658

72,592

        10         20         30         40         50         60 
MSRLLALLAL APLLAGAAET TAPKPPSAFT VEAQRRVEAE LPFADRADFE RADRGLIRRP 

        70         80         90        100        110        120 
ERLLIRNPDG SVAWQLGGYD FLLDGKPRDS INPSLQRQAL LNLKYGLFEV AEGIYQVRGF 

       130        140        150        160        170        180 
DLANITFIRG DSGWIVVDTL TTPATARAAY ELVSRELGER PIRTVIYSHA HADHFGGVRG 

       190        200        210        220        230        240 
LVEPQQVASG AVQIIAPAGF MEAAIKENVL AGNAMMRRAT YQYGTQLPKG PQGQVDMAIG 

       250        260        270        280        290        300 
KGLARGPLSL LAPTRLIEGE GEDLVLDGVP FTFQNTPGTE SPAEMNIWLP RQKALLMAEN 

       310        320        330        340        350        360 
VVGTLHNLYT LRGAEVRDAL GWSKYINQAL HRFGRQAEVM FAVHNWPRWG NAEIVEVLEK 

       370        380        390        400        410        420 
QRDLYGYLHD QTLHLANQGV TIGQVHNRLR LPPSLDQEWY DRGYHGSVSH NARAVLNRYL 

       430        440        450        460        470        480 
GYYDGNPATL DPLSPEDSAG RYVEYMGGAE RLLEQARASY ARGEYRWVVE VVNRLVFAEP 

       490        500        510        520        530        540 
DNRAARELQA DALEQLGYQA ENAGWRNSYL SAAYELRHGV PRDQPTMKAG SADALAAMDT 

       550        560        570        580        590        600 
GLLFDYLGVR LDAGAAEGKA LSINLRLPDI GENYLLELKN SHLNNLRGVQ SEDAGQTVSI 

       610        620        630        640        650 
DRADLNRLLL KEVSAVRLVF EGKLKSSGNP LLLGQLFGML GDFDFWFDIV TPAAKSEG

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References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen." Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P., Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M., Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y., Brody L.L., Coulter S.N., Folger K.R. Olson M.V. Nature 406:959-964(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.
[2]	"The crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa, defines a third class of sulfatases." Hagelueken G., Adams T.M., Wiehlmann L., Widow U., Kolmar H., Tummler B., Heinz D.W., Schubert W.D. Proc. Natl. Acad. Sci. U.S.A. 103:7631-7636(2006) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) IN COMPLEX WITH ZINC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE004091 Genomic DNA. Translation: AAG04129.1.

PIR

G83552.

RefSeq

NP_249431.1. NC_002516.2.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2CFU	X-ray	1.90	A	1-658	[»]
2CFZ	X-ray	2.05	A	1-658	[»]
2CG2	X-ray	2.10	A	1-658	[»]
2CG3	X-ray	2.60	A	1-658	[»]

ProteinModelPortal

Q9I5I9.

SMR

Q9I5I9. Positions 20-654.

ModBase

Search...

Protein-protein interaction databases

STRING

208964.PA0740.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

882069.

KEGG

pae:PA0740.

PATRIC

19835752. VBIPseAer58763_0769.

Organism-specific databases

PseudoCAP

PA0740.

Phylogenomic databases

OMA

KPRDSIN.

ProtClustDB

CLSK866081.

Family and domain databases

InterPro

IPR001279. Beta-lactamas-like.
IPR003033. SCP2_sterol-bd_dom.
[Graphical view]

Pfam

PF00753. Lactamase_B. 1 hit.
[Graphical view]

SMART

SM00849. Lactamase_B. 1 hit.
[Graphical view]

SUPFAM

SSF55718. SCP2. 1 hit.

ProtoNet

Search...

Other

EvolutionaryTrace

Q9I5I9.

Entry information

Entry name

Q9I5I9_PSEAE

Accession

Primary (citable) accession number: Q9I5I9

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2001
Last sequence update:	March 1, 2001
Last modified:	May 1, 2013
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)