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Protein
Submitted name:

SDS hydrolase SdsA1

Gene

sdsA1

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi169 – 1691Zinc 1; via tele nitrogenCombined sources
Metal bindingi171 – 1711Zinc 1; via pros nitrogenCombined sources
Metal bindingi173 – 1731Zinc 2Combined sources
Metal bindingi174 – 1741Zinc 2; via tele nitrogenCombined sources
Metal bindingi280 – 2801Zinc 1Combined sources
Metal bindingi299 – 2991Zinc 1Combined sources
Metal bindingi299 – 2991Zinc 2Combined sources
Metal bindingi344 – 3441Zinc 2; via tele nitrogenCombined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseImported

Keywords - Ligandi

Metal-bindingCombined sources, ZincCombined sources

Names & Taxonomyi

Protein namesi
Submitted name:
SDS hydrolase SdsA1Imported
Gene namesi
Name:sdsA1Imported
Ordered Locus Names:PA0740Imported
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)Imported
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA0740.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1717Sequence analysisAdd
BLAST
Chaini18 – 658641Sequence analysisPRO_5004328509Add
BLAST

Proteomic databases

PaxDbiQ9I5I9.

Interactioni

Protein-protein interaction databases

DIPiDIP-61164N.
STRINGi208964.PA0740.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2CFUX-ray1.90A1-658[»]
2CFZX-ray2.05A1-658[»]
2CG2X-ray2.10A1-658[»]
2CG3X-ray2.60A1-658[»]
5A23X-ray2.41A/B/C/D1-658[»]
5AIJX-ray1.95A1-658[»]
5AJLX-ray3.45A/B1-658[»]
ProteinModelPortaliQ9I5I9.
SMRiQ9I5I9. Positions 20-654.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9I5I9.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini122 – 344223Lactamase_BInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4105EUZ. Bacteria.
COG2015. LUCA.
InParanoidiQ9I5I9.
OMAiPWRSVYL.
OrthoDBiEOG6X10SN.
PhylomeDBiQ9I5I9.

Family and domain databases

Gene3Di3.30.1050.10. 1 hit.
3.60.15.10. 2 hits.
InterProiIPR029229. Alkyl_sulf_C.
IPR029228. Alkyl_sulf_dimr.
IPR001279. Metallo-B-lactamas.
IPR003033. SCP2_sterol-bd_dom.
[Graphical view]
PfamiPF14864. Alkyl_sulf_C. 1 hit.
PF14863. Alkyl_sulf_dimr. 1 hit.
PF00753. Lactamase_B. 1 hit.
[Graphical view]
SMARTiSM00849. Lactamase_B. 1 hit.
[Graphical view]
SUPFAMiSSF55718. SSF55718. 1 hit.
SSF56281. SSF56281. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9I5I9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRLLALLAL APLLAGAAET TAPKPPSAFT VEAQRRVEAE LPFADRADFE
60 70 80 90 100
RADRGLIRRP ERLLIRNPDG SVAWQLGGYD FLLDGKPRDS INPSLQRQAL
110 120 130 140 150
LNLKYGLFEV AEGIYQVRGF DLANITFIRG DSGWIVVDTL TTPATARAAY
160 170 180 190 200
ELVSRELGER PIRTVIYSHA HADHFGGVRG LVEPQQVASG AVQIIAPAGF
210 220 230 240 250
MEAAIKENVL AGNAMMRRAT YQYGTQLPKG PQGQVDMAIG KGLARGPLSL
260 270 280 290 300
LAPTRLIEGE GEDLVLDGVP FTFQNTPGTE SPAEMNIWLP RQKALLMAEN
310 320 330 340 350
VVGTLHNLYT LRGAEVRDAL GWSKYINQAL HRFGRQAEVM FAVHNWPRWG
360 370 380 390 400
NAEIVEVLEK QRDLYGYLHD QTLHLANQGV TIGQVHNRLR LPPSLDQEWY
410 420 430 440 450
DRGYHGSVSH NARAVLNRYL GYYDGNPATL DPLSPEDSAG RYVEYMGGAE
460 470 480 490 500
RLLEQARASY ARGEYRWVVE VVNRLVFAEP DNRAARELQA DALEQLGYQA
510 520 530 540 550
ENAGWRNSYL SAAYELRHGV PRDQPTMKAG SADALAAMDT GLLFDYLGVR
560 570 580 590 600
LDAGAAEGKA LSINLRLPDI GENYLLELKN SHLNNLRGVQ SEDAGQTVSI
610 620 630 640 650
DRADLNRLLL KEVSAVRLVF EGKLKSSGNP LLLGQLFGML GDFDFWFDIV

TPAAKSEG
Length:658
Mass (Da):72,592
Last modified:March 1, 2001 - v1
Checksum:i3D29B5D2B0A2A84F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG04129.1.
PIRiG83552.
RefSeqiNP_249431.1. NC_002516.2.
WP_003114166.1. NZ_ASJY01000117.1.

Genome annotation databases

EnsemblBacteriaiAAG04129; AAG04129; PA0740.
GeneIDi882069.
KEGGipae:PA0740.
PATRICi19835752. VBIPseAer58763_0769.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG04129.1.
PIRiG83552.
RefSeqiNP_249431.1. NC_002516.2.
WP_003114166.1. NZ_ASJY01000117.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2CFUX-ray1.90A1-658[»]
2CFZX-ray2.05A1-658[»]
2CG2X-ray2.10A1-658[»]
2CG3X-ray2.60A1-658[»]
5A23X-ray2.41A/B/C/D1-658[»]
5AIJX-ray1.95A1-658[»]
5AJLX-ray3.45A/B1-658[»]
ProteinModelPortaliQ9I5I9.
SMRiQ9I5I9. Positions 20-654.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-61164N.
STRINGi208964.PA0740.

Proteomic databases

PaxDbiQ9I5I9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG04129; AAG04129; PA0740.
GeneIDi882069.
KEGGipae:PA0740.
PATRICi19835752. VBIPseAer58763_0769.

Organism-specific databases

PseudoCAPiPA0740.

Phylogenomic databases

eggNOGiENOG4105EUZ. Bacteria.
COG2015. LUCA.
InParanoidiQ9I5I9.
OMAiPWRSVYL.
OrthoDBiEOG6X10SN.
PhylomeDBiQ9I5I9.

Miscellaneous databases

EvolutionaryTraceiQ9I5I9.

Family and domain databases

Gene3Di3.30.1050.10. 1 hit.
3.60.15.10. 2 hits.
InterProiIPR029229. Alkyl_sulf_C.
IPR029228. Alkyl_sulf_dimr.
IPR001279. Metallo-B-lactamas.
IPR003033. SCP2_sterol-bd_dom.
[Graphical view]
PfamiPF14864. Alkyl_sulf_C. 1 hit.
PF14863. Alkyl_sulf_dimr. 1 hit.
PF00753. Lactamase_B. 1 hit.
[Graphical view]
SMARTiSM00849. Lactamase_B. 1 hit.
[Graphical view]
SUPFAMiSSF55718. SSF55718. 1 hit.
SSF56281. SSF56281. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228Imported.
  2. "The crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa, defines a third class of sulfatases."
    Hagelueken G., Adams T.M., Wiehlmann L., Widow U., Kolmar H., Tummler B., Heinz D.W., Schubert W.D.
    Proc. Natl. Acad. Sci. U.S.A. 103:7631-7636(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) IN COMPLEX WITH ZINC.
  3. "Sdsa Polymorph Isolation and Improvement of Their Crystal Quality Using Nonconventional Crystallization Techniques."
    De La Mora E., Flores-Hernandez E., Jakoncic J., Stojanoff V., Siliqi D., Sanchez-Puig N., Moreno A.
    J. Appl. Crystallogr. 48:1551-1551(2015)
    Cited for: X-RAY CRYSTALLOGRAPHY (1.95 ANGSTROMS).

Entry informationi

Entry nameiQ9I5I9_PSEAE
AccessioniPrimary (citable) accession number: Q9I5I9
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: April 13, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.