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Q9I513

- PUR5_PSEAE

UniProt

Q9I513 - PUR5_PSEAE

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Protein

Phosphoribosylformylglycinamidine cyclo-ligase

Gene

purM

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation (EC:6.3.3.1UniRule annotation)
Alternative name(s):
AIR synthaseUniRule annotation
AIRSUniRule annotation
Phosphoribosyl-aminoimidazole synthetaseUniRule annotation
Gene namesi
Name:purMUniRule annotation
Ordered Locus Names:PA0945
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000002438: Chromosome

Organism-specific databases

PseudoCAPiPA0945.

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 353353Phosphoribosylformylglycinamidine cyclo-ligasePRO_0000148233Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi208964.PA0945.

Structurei

3D structure databases

ProteinModelPortaliQ9I513.
SMRiQ9I513. Positions 7-347.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0150.
HOGENOMiHOG000229090.
InParanoidiQ9I513.
KOiK01933.
OMAiEFEMYRT.
OrthoDBiEOG61CM1V.
PhylomeDBiQ9I513.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741. AIRS.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9I513-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSSKQPSLSY KDAGVDIDAG EALVERIKGV AKRTARPEVM GGLGGFGALC
60 70 80 90 100
EIPAGYKQPV LVSGTDGVGT KLRLALNLNK HDSIGQDLVA MCVNDLVVCG
110 120 130 140 150
AEPLFFLDYY ATGKLNVDVA ATVVTGIGAG CELAGCSLVG GETAEMPGMY
160 170 180 190 200
EGEDYDLAGF CVGVVEKAEI IDGSRVQAGD ALIALPSSGP HSNGYSLIRK
210 220 230 240 250
IIEVSGADIA QVQLDGKPLA DLLMAPTRIY VKPLLQLIKQ TGAVKAMAHI
260 270 280 290 300
TGGGLLDNIP RVLPDNAQAV IDVASWNRPA VFDWLQEQGN VDETEMHRVL
310 320 330 340 350
NCGVGMVICV AQSDAEKALE VLRAAGEQPW QIGRIETCGA DAERVVLNNL

KNH
Length:353
Mass (Da):37,123
Last modified:March 1, 2001 - v1
Checksum:iF50169F97482E553
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE004091 Genomic DNA. Translation: AAG04334.1.
PIRiA83529.
RefSeqiNP_249636.1. NC_002516.2.

Genome annotation databases

EnsemblBacteriaiAAG04334; AAG04334; PA0945.
GeneIDi879549.
KEGGipae:PA0945.
PATRICi19836186. VBIPseAer58763_0981.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE004091 Genomic DNA. Translation: AAG04334.1 .
PIRi A83529.
RefSeqi NP_249636.1. NC_002516.2.

3D structure databases

ProteinModelPortali Q9I513.
SMRi Q9I513. Positions 7-347.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 208964.PA0945.

Protocols and materials databases

DNASUi 879549.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAG04334 ; AAG04334 ; PA0945 .
GeneIDi 879549.
KEGGi pae:PA0945.
PATRICi 19836186. VBIPseAer58763_0981.

Organism-specific databases

PseudoCAPi PA0945.

Phylogenomic databases

eggNOGi COG0150.
HOGENOMi HOG000229090.
InParanoidi Q9I513.
KOi K01933.
OMAi EFEMYRT.
OrthoDBi EOG61CM1V.
PhylomeDBi Q9I513.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741. AIRS.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.

Entry informationi

Entry nameiPUR5_PSEAE
AccessioniPrimary (citable) accession number: Q9I513
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2003
Last sequence update: March 1, 2001
Last modified: October 29, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3