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Q9I4I1 (Q9I4I1_PSEAE) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribonucleoside-diphosphate reductase RuleBase RU003410
EC=1.17.4.1 RuleBase RU003410
Gene names
Name:nrdA EMBL AAG04545.1
Ordered Locus Names:PA1156
OrganismPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Taxonomic identifier208964 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length963 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides By similarity. RuleBase RU003410

Catalytic activity

2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. RuleBase RU003410

Pathway

Genetic information processing; DNA replication. RuleBase RU003410

Sequence similarities

Belongs to the ribonucleoside diphosphate reductase large chain family. RuleBase RU003410

Sequences

Sequence LengthMass (Da)Tools
Q9I4I1 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: 39B810E21AFD44BE

FASTA963107,106
        10         20         30         40         50         60 
MHTDTTRENP QASAPQAADS SQDLAATAPG QLRVIKRNGT VVPYTDDKIT VAITKAFLAV 

        70         80         90        100        110        120 
EGGTAAASSR IHDTVRRLTE QVTATFKRRM PSGGTIHIEE IQDQVELALM RAGEQKVARD 

       130        140        150        160        170        180 
YVIYREARAA ERKNAGAASD VAQPHPSIRI TRADGSLSPL DMGRLNTIIS EACEGLAEVD 

       190        200        210        220        230        240 
GALIERETLK NLYDGVAEKD VNTALVMTAR TLVEREPNYS YVTARLLMDT LRAEALGFLG 

       250        260        270        280        290        300 
VAESATHHEM AELYAKALPA YIEKGAEFEL VDAKLKEFDL EKLGKAIDHE RDQQFTYLGL 

       310        320        330        340        350        360 
QTLYDRYFIH KDGIRFELPQ IFFMRVAMGL AIEEKDREAR AIEFYNLLSS FDYMSSTPTL 

       370        380        390        400        410        420 
FNAGTLRPQL SSCYLTTVPD DLSGIYGAIH DNAMLSKFAG GLGNDWTPVR ALGSYIKGTN 

       430        440        450        460        470        480 
GKSQGVVPFL KVVNDTAVAV NQGGKRKGAV CAYLETWHLD IEEFLELRKN TGDDRRRTHD 

       490        500        510        520        530        540 
MNTANWIPDL FMKRVFDDGS WTLFSPSDVP DLHDLYGKAF EERYEYYEAL ASYGKLKLHK 

       550        560        570        580        590        600 
VVQAKDLWRK MLSMLFETGH PWLTFKDPCN LRSPQQHVGV VHSSNLCTEI TLNTNKDEIA 

       610        620        630        640        650        660 
VCNLGSINLV NHIVDGKLDT AKLEKTVKTA VRMLDNVIDI NYYSVPQAQN SNFKHRPVGL 

       670        680        690        700        710        720 
GIMGFQDALY LQHIPYGSDA AIAFADQSME AISYYAIQAS CDLADERGAY QTFQGSLWSQ 

       730        740        750        760        770        780 
GILPIDSEKK LIEERGAKYI EVDLSETLDW APLRERVQKG IRNSNIMAIA PTATIANITG 

       790        800        810        820        830        840 
VSQSIEPTYQ NLYVKSNLSG EFTVINPYLV RDLKARGLWD PVMVNDLKYY DGSVQQIERI 

       850        860        870        880        890        900 
PQDLKDLYAT AFEVETRWIV EAASRRQKWI DQAQSLNLYI AGASGKKLDV TYRMAWFRGL 

       910        920        930        940        950        960 
KTTYYLRALA ATSTEKSTIN TGKLNAVSAG GNDGLQAAPA AEPKPAPVPQ ACSIDNPDCE 


ACQ

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE004091 Genomic DNA. Translation: AAG04545.1.
PIRB83502.
RefSeqNP_249847.1. NC_002516.2.

3D structure databases

HSSPHSSP built from PDB template 3R1R based on UniProtKB P00452.
ProteinModelPortalQ9I4I1.
ModBaseSearch...

Proteomic databases

PRIDEQ9I4I1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID877716.
GenomeReviewsGene locus PA1156 in contig AE004091_GR.
KEGGpae:PA1156.
PATRIC19836630. VBIPseAer58763_1201.

Organism-specific databases

PseudoCAPPA1156.

Phylogenomic databases

HOGENOMHBG296647.
OMASMEAVSY.
ProtClustDBPRK07207.

Enzyme and pathway databases

BioCycPAER208964:PA1156-MONOMER.

Family and domain databases

InterProIPR005144. ATP-cone.
IPR013346. NrdE_NrdA.
IPR013509. Ribncl_Rdtase_lsu_N.
IPR000788. Ribncl_red_lg_C.
IPR008926. Ribnucl_Rdtase_R1-su_N.
[Graphical view]
KOK00525.
PfamPF03477. ATP-cone. 2 hits.
PF02867. Ribonuc_red_lgC. 1 hit.
PF00317. Ribonuc_red_lgN. 1 hit.
[Graphical view]
PRINTSPR01183. RIBORDTASEM1.
SUPFAMSSF48168. Ribonucleo_red_N. 1 hit.
TIGRFAMsTIGR02506. NrdE_NrdA. 1 hit.
PROSITEPS51161. ATP_CONE. 2 hits.
PS00089. RIBORED_LARGE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ9I4I1_PSEAE
AccessionPrimary (citable) accession number: Q9I4I1
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: December 14, 2011
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info