Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9I469

- COBD_PSEAE

UniProt

Q9I469 - COBD_PSEAE

Protein

Cobalamin biosynthesis protein CobD

Gene

cobD

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 74 (01 Oct 2014)
      Sequence version 1 (01 Mar 2001)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.By similarity

    Pathwayi

    GO - Molecular functioni

    1. cobalamin-transporting ATPase activity Source: UniProtKB-HAMAP
    2. threonine-phosphate decarboxylase activity Source: InterPro

    GO - Biological processi

    1. cobalamin biosynthetic process Source: UniProtKB-UniPathway
    2. porphyrin-containing compound biosynthetic process Source: UniProtKB-KW

    Keywords - Biological processi

    Cobalamin biosynthesis, Porphyrin biosynthesis

    Enzyme and pathway databases

    UniPathwayiUPA00148.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cobalamin biosynthesis protein CobD
    Gene namesi
    Name:cobD
    Ordered Locus Names:PA1275
    OrganismiPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
    Taxonomic identifieri208964 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
    ProteomesiUP000002438: Chromosome

    Organism-specific databases

    PseudoCAPiPA1275.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 312312Cobalamin biosynthesis protein CobDPRO_0000287753Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi208964.PA1275.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei59 – 7921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei81 – 10121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei153 – 17321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei241 – 26121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei292 – 31221HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the CobD/CbiB family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG1270.
    HOGENOMiHOG000290070.
    KOiK02227.
    OMAiHRSPRYA.
    OrthoDBiEOG6VXFC9.
    PhylomeDBiQ9I469.

    Family and domain databases

    HAMAPiMF_00024. CobD_CbiB.
    InterProiIPR004485. Cobalamin_biosynth_CobD/CbiB.
    [Graphical view]
    PfamiPF03186. CobD_Cbib. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00380. cobD. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q9I469-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSALLGILGV VLDARFGEPQ GWHPLVAFGR LADRLERRFN RSRLAGEADP    50
    GVGWRSHGVT AWVLAVLPLT LLAWALAELP YLGWLVQALA LYAALGLRSL 100
    GEHAEPVALA LRAGDLDEAR RRVGYLVSRD TRELDQAGVA RAATESVLEN 150
    GSDAVYAALF WFAVAGAPGV VLYRLSNTLD AMWGYRNARF ERFGWAAAKI 200
    DDILNYLPAR LVALTYALLG DTRQALRCWR EQAPQWDSPN AGPVMAAGAG 250
    ALGVFLGGAA IYHGELHQRP LLGSGPQPQG RDIYRALALV RQGVLLWLLV 300
    LAGLWAMGWL HA 312
    Length:312
    Mass (Da):33,873
    Last modified:March 1, 2001 - v1
    Checksum:iC74A880A7F474347
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE004091 Genomic DNA. Translation: AAG04664.1.
    PIRiA83486.
    RefSeqiNP_249966.1. NC_002516.2.

    Genome annotation databases

    EnsemblBacteriaiAAG04664; AAG04664; PA1275.
    GeneIDi881384.
    KEGGipae:PA1275.
    PATRICi19836878. VBIPseAer58763_1325.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE004091 Genomic DNA. Translation: AAG04664.1 .
    PIRi A83486.
    RefSeqi NP_249966.1. NC_002516.2.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 208964.PA1275.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAG04664 ; AAG04664 ; PA1275 .
    GeneIDi 881384.
    KEGGi pae:PA1275.
    PATRICi 19836878. VBIPseAer58763_1325.

    Organism-specific databases

    PseudoCAPi PA1275.

    Phylogenomic databases

    eggNOGi COG1270.
    HOGENOMi HOG000290070.
    KOi K02227.
    OMAi HRSPRYA.
    OrthoDBi EOG6VXFC9.
    PhylomeDBi Q9I469.

    Enzyme and pathway databases

    UniPathwayi UPA00148 .

    Family and domain databases

    HAMAPi MF_00024. CobD_CbiB.
    InterProi IPR004485. Cobalamin_biosynth_CobD/CbiB.
    [Graphical view ]
    Pfami PF03186. CobD_Cbib. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00380. cobD. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.

    Entry informationi

    Entry nameiCOBD_PSEAE
    AccessioniPrimary (citable) accession number: Q9I469
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 15, 2007
    Last sequence update: March 1, 2001
    Last modified: October 1, 2014
    This is version 74 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3