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Q9I377

- Q9I377_PSEAE

UniProt

Q9I377 - Q9I377_PSEAE

Protein
Submitted name:

Probable oxidoreductase

Gene

PA1648

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (01 Mar 2001)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei180 – 1801NADP; via amide nitrogenImported
    Binding sitei184 – 1841NADPImported
    Binding sitei200 – 2001NADPImported
    Binding sitei223 – 2231NADPImported
    Binding sitei326 – 3261NADPImported

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi159 – 1602NADPImported
    Nucleotide bindingi245 – 2517NADPImported
    Nucleotide bindingi276 – 2783NADPImported

    GO - Molecular functioni

    1. nucleotide binding Source: UniProtKB-KW
    2. oxidoreductase activity Source: InterPro
    3. zinc ion binding Source: InterPro

    Keywords - Ligandi

    NADPImported, Nucleotide-bindingImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Probable oxidoreductaseImported
    Gene namesi
    Ordered Locus Names:PA1648Imported
    OrganismiPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)Imported
    Taxonomic identifieri208964 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
    ProteomesiUP000002438: Chromosome

    Organism-specific databases

    PseudoCAPiPA1648.

    Interactioni

    Protein-protein interaction databases

    STRINGi208964.PA1648.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4B7CX-ray2.10A/B/C/D/E/F/G/H/I/J/K/L1-334[»]
    4B7XX-ray2.20A/B/C/D/E/F/G/H/I/J/K/L1-334[»]
    ProteinModelPortaliQ9I377.
    SMRiQ9I377. Positions 4-334.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000294663.
    KOiK07119.
    OMAiANYNNGR.
    OrthoDBiEOG6MSS2K.
    PhylomeDBiQ9I377.

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    3.90.180.10. 1 hit.
    InterProiIPR013149. ADH_C.
    IPR002085. ADH_SF_Zn-type.
    IPR011032. GroES-like.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PANTHERiPTHR11695. PTHR11695. 1 hit.
    PfamiPF00107. ADH_zinc_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF50129. SSF50129. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q9I377-1 [UniParc]FASTAAdd to Basket

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    MTSQINRQYQ LAQRPSGLPG RDTFSFVETP LGEPAEGQIL VKNEYLSLDP    50
    AMRGWMNDAR SYIPPVGIGE VMRALGVGKV LVSKHPGFQA GDYVNGALGV 100
    QDYFIGEPKG FYKVDPSRAP LPRYLSALGM TGMTAYFALL DVGQPKNGET 150
    VVISGAAGAV GSVAGQIARL KGCRVVGIAG GAEKCRFLVE ELGFDGAIDY 200
    KNEDLAAGLK RECPKGIDVF FDNVGGEILD TVLTRIAFKA RIVLCGAISQ 250
    YNNKEAVRGP ANYLSLLVNR ARMEGMVVMD YAQRFPEGLK EMATWLAEGK 300
    LQSREDIVEG LETFPETLLK LFSGENFGKL VLKV 334
    Length:334
    Mass (Da):36,169
    Last modified:March 1, 2001 - v1
    Checksum:i8294AD44FEA5CE43
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE004091 Genomic DNA. Translation: AAG05037.1.
    PIRiE83440.
    RefSeqiNP_250339.1. NC_002516.2.

    Genome annotation databases

    EnsemblBacteriaiAAG05037; AAG05037; PA1648.
    GeneIDi882158.
    KEGGipae:PA1648.
    PATRICi19837647. VBIPseAer58763_1709.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE004091 Genomic DNA. Translation: AAG05037.1 .
    PIRi E83440.
    RefSeqi NP_250339.1. NC_002516.2.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4B7C X-ray 2.10 A/B/C/D/E/F/G/H/I/J/K/L 1-334 [» ]
    4B7X X-ray 2.20 A/B/C/D/E/F/G/H/I/J/K/L 1-334 [» ]
    ProteinModelPortali Q9I377.
    SMRi Q9I377. Positions 4-334.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 208964.PA1648.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAG05037 ; AAG05037 ; PA1648 .
    GeneIDi 882158.
    KEGGi pae:PA1648.
    PATRICi 19837647. VBIPseAer58763_1709.

    Organism-specific databases

    PseudoCAPi PA1648.

    Phylogenomic databases

    HOGENOMi HOG000294663.
    KOi K07119.
    OMAi ANYNNGR.
    OrthoDBi EOG6MSS2K.
    PhylomeDBi Q9I377.

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    3.90.180.10. 1 hit.
    InterProi IPR013149. ADH_C.
    IPR002085. ADH_SF_Zn-type.
    IPR011032. GroES-like.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    PANTHERi PTHR11695. PTHR11695. 1 hit.
    Pfami PF00107. ADH_zinc_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50129. SSF50129. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228Imported.
    2. "The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery."
      Moynie L., Schnell R., McMahon S.A., Sandalova T., Boulkerou W.A., Schmidberger J.W., Alphey M., Cukier C., Duthie F., Kopec J., Liu H., Jacewicz A., Hunter W.N., Naismith J.H., Schneider G.
      Acta Crystallogr. F 69:25-34(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) IN COMPLEX WITH NADP.

    Entry informationi

    Entry nameiQ9I377_PSEAE
    AccessioniPrimary (citable) accession number: Q9I377
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2001
    Last sequence update: March 1, 2001
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3