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Protein
Submitted name:

Probable oxidoreductase

Gene

PA1648

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei180 – 1801NADP; via amide nitrogenCombined sources
Binding sitei184 – 1841NADPCombined sources
Binding sitei200 – 2001NADPCombined sources
Binding sitei223 – 2231NADPCombined sources
Binding sitei326 – 3261NADPCombined sources

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi159 – 1602NADPCombined sources
Nucleotide bindingi245 – 2517NADPCombined sources
Nucleotide bindingi276 – 2783NADPCombined sources

GO - Molecular functioni

  1. nucleotide binding Source: UniProtKB-KW
  2. oxidoreductase activity Source: InterPro
  3. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Ligandi

NADPCombined sources, Nucleotide-bindingCombined sources

Names & Taxonomyi

Protein namesi
Submitted name:
Probable oxidoreductaseImported
Gene namesi
Ordered Locus Names:PA1648Imported
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)Imported
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA1648.

Interactioni

Protein-protein interaction databases

STRINGi208964.PA1648.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4B7CX-ray2.10A/B/C/D/E/F/G/H/I/J/K/L1-334[»]
4B7XX-ray2.20A/B/C/D/E/F/G/H/I/J/K/L1-334[»]
ProteinModelPortaliQ9I377.
SMRiQ9I377. Positions 4-334.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000294663.
InParanoidiQ9I377.
KOiK07119.
OMAiTEIAPVQ.
OrthoDBiEOG6MSS2K.
PhylomeDBiQ9I377.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
3.90.180.10. 1 hit.
InterProiIPR013149. ADH_C.
IPR002085. ADH_SF_Zn-type.
IPR011032. GroES-like.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11695. PTHR11695. 1 hit.
PfamiPF00107. ADH_zinc_N. 1 hit.
[Graphical view]
SUPFAMiSSF50129. SSF50129. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9I377-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSQINRQYQ LAQRPSGLPG RDTFSFVETP LGEPAEGQIL VKNEYLSLDP
60 70 80 90 100
AMRGWMNDAR SYIPPVGIGE VMRALGVGKV LVSKHPGFQA GDYVNGALGV
110 120 130 140 150
QDYFIGEPKG FYKVDPSRAP LPRYLSALGM TGMTAYFALL DVGQPKNGET
160 170 180 190 200
VVISGAAGAV GSVAGQIARL KGCRVVGIAG GAEKCRFLVE ELGFDGAIDY
210 220 230 240 250
KNEDLAAGLK RECPKGIDVF FDNVGGEILD TVLTRIAFKA RIVLCGAISQ
260 270 280 290 300
YNNKEAVRGP ANYLSLLVNR ARMEGMVVMD YAQRFPEGLK EMATWLAEGK
310 320 330
LQSREDIVEG LETFPETLLK LFSGENFGKL VLKV
Length:334
Mass (Da):36,169
Last modified:February 28, 2001 - v1
Checksum:i8294AD44FEA5CE43
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG05037.1.
PIRiE83440.
RefSeqiNP_250339.1. NC_002516.2.

Genome annotation databases

EnsemblBacteriaiAAG05037; AAG05037; PA1648.
GeneIDi882158.
KEGGipae:PA1648.
PATRICi19837647. VBIPseAer58763_1709.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG05037.1.
PIRiE83440.
RefSeqiNP_250339.1. NC_002516.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4B7CX-ray2.10A/B/C/D/E/F/G/H/I/J/K/L1-334[»]
4B7XX-ray2.20A/B/C/D/E/F/G/H/I/J/K/L1-334[»]
ProteinModelPortaliQ9I377.
SMRiQ9I377. Positions 4-334.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi208964.PA1648.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG05037; AAG05037; PA1648.
GeneIDi882158.
KEGGipae:PA1648.
PATRICi19837647. VBIPseAer58763_1709.

Organism-specific databases

PseudoCAPiPA1648.

Phylogenomic databases

HOGENOMiHOG000294663.
InParanoidiQ9I377.
KOiK07119.
OMAiTEIAPVQ.
OrthoDBiEOG6MSS2K.
PhylomeDBiQ9I377.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
3.90.180.10. 1 hit.
InterProiIPR013149. ADH_C.
IPR002085. ADH_SF_Zn-type.
IPR011032. GroES-like.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11695. PTHR11695. 1 hit.
PfamiPF00107. ADH_zinc_N. 1 hit.
[Graphical view]
SUPFAMiSSF50129. SSF50129. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228Imported.
  2. "The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery."
    Moynie L., Schnell R., McMahon S.A., Sandalova T., Boulkerou W.A., Schmidberger J.W., Alphey M., Cukier C., Duthie F., Kopec J., Liu H., Jacewicz A., Hunter W.N., Naismith J.H., Schneider G.
    Acta Crystallogr. F 69:25-34(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) IN COMPLEX WITH NADP.

Entry informationi

Entry nameiQ9I377_PSEAE
AccessioniPrimary (citable) accession number: Q9I377
Entry historyi
Integrated into UniProtKB/TrEMBL: February 28, 2001
Last sequence update: February 28, 2001
Last modified: January 6, 2015
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.