Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Probable epoxide hydrolase

Gene

PA2086

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. hydrolase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
Probable epoxide hydrolaseImported
Gene namesi
Ordered Locus Names:PA2086Imported
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)Imported
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000002438: Chromosome

Organism-specific databases

PseudoCAPiPA2086.

Interactioni

Protein-protein interaction databases

STRINGi208964.PA2086.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4B9EX-ray1.40A1-300[»]
4BATX-ray1.30A1-300[»]
4BAUX-ray1.55A1-300[»]
4BAZX-ray1.35A1-300[»]
4BB0X-ray1.77A1-300[»]
ProteinModelPortaliQ9I229.
SMRiQ9I229. Positions 4-299.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000028073.
InParanoidiQ9I229.
KOiK01561.
OMAiHFMAEEA.
OrthoDBiEOG647TWF.
PhylomeDBiQ9I229.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000639. Epox_hydrolase-like.
[Graphical view]
PRINTSiPR00412. EPOXHYDRLASE.
SUPFAMiSSF53474. SSF53474. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9I229-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNTDPLLPGF DYLTLHTSAA RLRVAVKGSG PPLLLLHGYP QTHLAWHRIA
60 70 80 90 100
PRLAEDYSVV LADLRGYGES RALDEEGADY SKAALARDQL ETMGQLGFER
110 120 130 140 150
FAVIGHDRGA RVGYRLALDH PQAVAAFVSL TVVPILDNWA AVNKVFALNA
160 170 180 190 200
YHWFLLAQPY DLPERLIGAD PEHFLDYTLR RMAQGRDIYH PQALESYRRA
210 220 230 240 250
FRDPAVRHAM CEDYRAAVGV DADADQADRD AGRRLQCPVQ VLWQERPYAA
260 270 280 290 300
GQHPLEIWKT WAGQVEGAAI GASHMLPEDA PDAVLEHLLG FLASHREALR
Length:300
Mass (Da):33,485
Last modified:March 1, 2001 - v1
Checksum:i993122FF5635032F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG05474.1.
PIRiH83384.
RefSeqiNP_250776.1. NC_002516.2.

Genome annotation databases

EnsemblBacteriaiAAG05474; AAG05474; PA2086.
GeneIDi882121.
KEGGipae:PA2086.
PATRICi19838596. VBIPseAer58763_2178.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG05474.1.
PIRiH83384.
RefSeqiNP_250776.1. NC_002516.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4B9EX-ray1.40A1-300[»]
4BATX-ray1.30A1-300[»]
4BAUX-ray1.55A1-300[»]
4BAZX-ray1.35A1-300[»]
4BB0X-ray1.77A1-300[»]
ProteinModelPortaliQ9I229.
SMRiQ9I229. Positions 4-299.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi208964.PA2086.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG05474; AAG05474; PA2086.
GeneIDi882121.
KEGGipae:PA2086.
PATRICi19838596. VBIPseAer58763_2178.

Organism-specific databases

PseudoCAPiPA2086.

Phylogenomic databases

HOGENOMiHOG000028073.
InParanoidiQ9I229.
KOiK01561.
OMAiHFMAEEA.
OrthoDBiEOG647TWF.
PhylomeDBiQ9I229.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000639. Epox_hydrolase-like.
[Graphical view]
PRINTSiPR00412. EPOXHYDRLASE.
SUPFAMiSSF53474. SSF53474. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228Imported.
  2. "Structure of a Putative Epoxide Hydrolase Mutant."
    Schmidberger J.W., Schnell R., Schneider G.
    Submitted (SEP-2012) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.77 ANGSTROMS).
  3. "Structure of a Putative Epoxide Hydrolase Q244E Mutant from Pseudomonas Aeruginosa."
    Schmidberger J.W., Schnell R., Schneider G.
    Submitted (SEP-2012) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.35 ANGSTROMS).
  4. "Structure of a Putative Epoxide Hydrolase T131D Mutant from Pseudomonas Aeruginosa, with Bound Mfa."
    Schmidberger J.W., Schnell R., Schneider G.
    Submitted (SEP-2012) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.55 ANGSTROMS).
  5. "Structure of a Putative Epoxide Hydrolase T131D Mutant from Pseudomonas Aeruginosa."
    Schmidberger J.W., Schnell R., Schneider G.
    Submitted (SEP-2012) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.30 ANGSTROMS).
  6. "The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery."
    Moynie L., Schnell R., McMahon S.A., Sandalova T., Boulkerou W.A., Schmidberger J.W., Alphey M., Cukier C., Duthie F., Kopec J., Liu H., Jacewicz A., Hunter W.N., Naismith J.H., Schneider G.
    Acta Crystallogr. F 69:25-34(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.40 ANGSTROMS).

Entry informationi

Entry nameiQ9I229_PSEAE
AccessioniPrimary (citable) accession number: Q9I229
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: February 4, 2015
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.