Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9I229

- Q9I229_PSEAE

UniProt

Q9I229 - Q9I229_PSEAE

Protein
Submitted name:

Probable epoxide hydrolase

Gene

PA2086

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 75 (01 Oct 2014)
      Sequence version 1 (01 Mar 2001)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei14 – 141Sulfate 2Imported
    Binding sitei14 – 141Sulfate 3Imported
    Binding sitei23 – 231Sulfate 2Imported
    Binding sitei23 – 231Sulfate 3Imported
    Binding sitei48 – 481Sulfate 1Imported
    Binding sitei48 – 481Sulfate 5Imported
    Binding sitei48 – 481Sulfate 6Imported
    Binding sitei52 – 521Sulfate 7Imported
    Binding sitei65 – 651Sulfate 4Imported
    Binding sitei87 – 871Sulfate 4Imported
    Binding sitei111 – 1111Chloride 1Imported
    Binding sitei111 – 1111Chloride 2Imported
    Binding sitei149 – 1491Sulfate 12Imported
    Binding sitei176 – 1761Sulfate 14; via carbonyl oxygenImported
    Binding sitei180 – 1801Sulfate 14Imported
    Binding sitei198 – 1981Sulfate 15Imported
    Binding sitei199 – 1991Sulfate 16Imported
    Binding sitei214 – 2141Sulfate 8Imported
    Binding sitei226 – 2261Sulfate 17Imported
    Binding sitei229 – 2291Sulfate 18Imported
    Binding sitei233 – 2331Sulfate 10Imported
    Binding sitei274 – 2741Sulfate 11Imported
    Binding sitei274 – 2741Sulfate 13Imported
    Binding sitei274 – 2741Sulfate 8Imported

    GO - Molecular functioni

    1. hydrolase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    HydrolaseImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Probable epoxide hydrolaseImported
    Gene namesi
    Ordered Locus Names:PA2086Imported
    OrganismiPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)Imported
    Taxonomic identifieri208964 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
    ProteomesiUP000002438: Chromosome

    Organism-specific databases

    PseudoCAPiPA2086.

    Interactioni

    Protein-protein interaction databases

    STRINGi208964.PA2086.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4B9AX-ray1.45A1-300[»]
    4B9EX-ray1.40A1-300[»]
    4BATX-ray1.30A1-300[»]
    4BAUX-ray1.55A1-300[»]
    4BAZX-ray1.35A1-300[»]
    4BB0X-ray1.77A1-300[»]
    ProteinModelPortaliQ9I229.
    SMRiQ9I229. Positions 4-299.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni107 – 1115Sulfate 8 bindingImported
    Regioni120 – 1234Sulfate 9 bindingImported
    Regioni152 – 1532Sulfate 13 bindingImported
    Regioni152 – 1532Sulfate 8 bindingImported
    Regioni234 – 2363Sulfate 19 bindingImported
    Regioni244 – 2463Sulfate 11 bindingImported
    Regioni260 – 2612Sulfate 18 bindingImported
    Regioni281 – 2833Sulfate 21 bindingImported
    Regioni295 – 2984Sulfate 20 bindingImported

    Phylogenomic databases

    HOGENOMiHOG000028073.
    KOiK01561.
    OMAiTHVIWHK.
    OrthoDBiEOG647TWF.
    PhylomeDBiQ9I229.

    Family and domain databases

    Gene3Di3.40.50.1820. 1 hit.
    InterProiIPR029058. AB_hydrolase.
    IPR000639. Epox_hydrolase-like.
    [Graphical view]
    PRINTSiPR00412. EPOXHYDRLASE.
    SUPFAMiSSF53474. SSF53474. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q9I229-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNTDPLLPGF DYLTLHTSAA RLRVAVKGSG PPLLLLHGYP QTHLAWHRIA    50
    PRLAEDYSVV LADLRGYGES RALDEEGADY SKAALARDQL ETMGQLGFER 100
    FAVIGHDRGA RVGYRLALDH PQAVAAFVSL TVVPILDNWA AVNKVFALNA 150
    YHWFLLAQPY DLPERLIGAD PEHFLDYTLR RMAQGRDIYH PQALESYRRA 200
    FRDPAVRHAM CEDYRAAVGV DADADQADRD AGRRLQCPVQ VLWQERPYAA 250
    GQHPLEIWKT WAGQVEGAAI GASHMLPEDA PDAVLEHLLG FLASHREALR 300
    Length:300
    Mass (Da):33,485
    Last modified:March 1, 2001 - v1
    Checksum:i993122FF5635032F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE004091 Genomic DNA. Translation: AAG05474.1.
    PIRiH83384.
    RefSeqiNP_250776.1. NC_002516.2.

    Genome annotation databases

    EnsemblBacteriaiAAG05474; AAG05474; PA2086.
    GeneIDi882121.
    KEGGipae:PA2086.
    PATRICi19838596. VBIPseAer58763_2178.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE004091 Genomic DNA. Translation: AAG05474.1 .
    PIRi H83384.
    RefSeqi NP_250776.1. NC_002516.2.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4B9A X-ray 1.45 A 1-300 [» ]
    4B9E X-ray 1.40 A 1-300 [» ]
    4BAT X-ray 1.30 A 1-300 [» ]
    4BAU X-ray 1.55 A 1-300 [» ]
    4BAZ X-ray 1.35 A 1-300 [» ]
    4BB0 X-ray 1.77 A 1-300 [» ]
    ProteinModelPortali Q9I229.
    SMRi Q9I229. Positions 4-299.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 208964.PA2086.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAG05474 ; AAG05474 ; PA2086 .
    GeneIDi 882121.
    KEGGi pae:PA2086.
    PATRICi 19838596. VBIPseAer58763_2178.

    Organism-specific databases

    PseudoCAPi PA2086.

    Phylogenomic databases

    HOGENOMi HOG000028073.
    KOi K01561.
    OMAi THVIWHK.
    OrthoDBi EOG647TWF.
    PhylomeDBi Q9I229.

    Family and domain databases

    Gene3Di 3.40.50.1820. 1 hit.
    InterProi IPR029058. AB_hydrolase.
    IPR000639. Epox_hydrolase-like.
    [Graphical view ]
    PRINTSi PR00412. EPOXHYDRLASE.
    SUPFAMi SSF53474. SSF53474. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228Imported.
    2. "Structure of a Putative Epoxide Hydrolase Mutant."
      Schmidberger J.W., Schnell R., Schneider G.
      Submitted (SEP-2012) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.77 ANGSTROMS).
    3. "Structure of a Putative Epoxide Hydrolase Q244E Mutant from Pseudomonas Aeruginosa."
      Schmidberger J.W., Schnell R., Schneider G.
      Submitted (SEP-2012) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.35 ANGSTROMS).
    4. "Structure of a Putative Epoxide Hydrolase T131D Mutant from Pseudomonas Aeruginosa, with Bound Mfa."
      Schmidberger J.W., Schnell R., Schneider G.
      Submitted (SEP-2012) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.55 ANGSTROMS).
    5. "Structure of a Putative Epoxide Hydrolase T131D Mutant from Pseudomonas Aeruginosa."
      Schmidberger J.W., Schnell R., Schneider G.
      Submitted (SEP-2012) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.30 ANGSTROMS).
    6. "The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery."
      Moynie L., Schnell R., McMahon S.A., Sandalova T., Boulkerou W.A., Schmidberger J.W., Alphey M., Cukier C., Duthie F., Kopec J., Liu H., Jacewicz A., Hunter W.N., Naismith J.H., Schneider G.
      Acta Crystallogr. F 69:25-34(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.40 ANGSTROMS).

    Entry informationi

    Entry nameiQ9I229_PSEAE
    AccessioniPrimary (citable) accession number: Q9I229
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2001
    Last sequence update: March 1, 2001
    Last modified: October 1, 2014
    This is version 75 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3