ID   GLGA_PSEAE              Reviewed;         513 AA.
AC   Q9I1V0;
DT   16-NOV-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   27-MAR-2024, entry version 110.
DE   RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE            EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE   AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN   Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=PA2165;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 /
RC   1C / PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
CC   -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC         alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC         COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC         ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC   -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC       Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC       Rule:MF_00484}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE004091; AAG05553.1; -; Genomic_DNA.
DR   PIR; H83375; H83375.
DR   RefSeq; NP_250855.1; NC_002516.2.
DR   RefSeq; WP_003115521.1; NZ_QZGE01000014.1.
DR   AlphaFoldDB; Q9I1V0; -.
DR   SMR; Q9I1V0; -.
DR   STRING; 208964.PA2165; -.
DR   CAZy; GT5; Glycosyltransferase Family 5.
DR   PaxDb; 208964-PA2165; -.
DR   GeneID; 881026; -.
DR   KEGG; pae:PA2165; -.
DR   PATRIC; fig|208964.12.peg.2265; -.
DR   PseudoCAP; PA2165; -.
DR   HOGENOM; CLU_009583_18_4_6; -.
DR   InParanoid; Q9I1V0; -.
DR   OrthoDB; 9808590at2; -.
DR   PhylomeDB; Q9I1V0; -.
DR   BioCyc; PAER208964:G1FZ6-2205-MONOMER; -.
DR   UniPathway; UPA00164; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR   GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR   CDD; cd03791; GT5_Glycogen_synthase_DULL1-like; 1.
DR   Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR   HAMAP; MF_00484; Glycogen_synth; 1.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR011835; GS/SS.
DR   InterPro; IPR013534; Starch_synth_cat_dom.
DR   NCBIfam; TIGR02095; glgA; 1.
DR   PANTHER; PTHR45825:SF8; GLYCOGEN SYNTHASE; 1.
DR   PANTHER; PTHR45825; GRANULE-BOUND STARCH SYNTHASE 1, CHLOROPLASTIC/AMYLOPLASTIC; 1.
DR   Pfam; PF08323; Glyco_transf_5; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE   3: Inferred from homology;
KW   Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW   Transferase.
FT   CHAIN           1..513
FT                   /note="Glycogen synthase"
FT                   /id="PRO_0000188632"
FT   BINDING         47
FT                   /ligand="ADP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:57498"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ   SEQUENCE   513 AA;  56562 MW;  66585F86FAA8AB9C CRC64;
     MGHSVAGVCL EEPAVLTAFP SLLHPQDPPQ QRDRILFVTA ELSDFVKVGG LGDFSAALPR
     VLKREHSVRV LLPGYRQVLE RCRDLRIIGS LPGRAAIPPC EIGLVTLDDG LEVMLVLCPL
     LYEREGTPYM DDQGNDWPDN HLRFARLCLA AAEIAGGRGA QGWQPGLVHA NDWPSALTPA
     YMAWNGVRTP SLFTIHNLAY QGLCDLQCSA ELGLPDEALS HESMEFHGRL SFLKAGIAHA
     HHITTVSETY AQEITTPEYG CGLHGILKYK VEKRQLSGIV NGIDDSWQPH CDPHLVACFS
     ARQWAGKRAN TRYVEERFGL EPGKGPLFAV VSRLVQQKGI DLTLEISDAL LQAGGRLVSI
     GRGEPNLEKA MLELARRHPG QVGVHIGFDE TEARRIYAGS DFLLMPSRYE PCGLSQLYAQ
     CFGSLPIARC TGGLADTIVD GVTGFLFREE TAQSYLDAVM RAINVYHCPS LLNAMRCKAM
     AAPMFWSDSV EPYNRLYRRL LRNTAPALRG VRQ
//