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Protein
Submitted name:

Probable transcriptional regulator

Gene

PA2196

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. transcription regulatory region sequence-specific DNA binding Source: PseudoCAP

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotationSAAS annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Probable transcriptional regulatorImported
Gene namesi
Ordered Locus Names:PA2196Imported
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)Imported
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA2196.

Interactioni

Protein-protein interaction databases

STRINGi208964.PA2196.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3RD3X-ray2.40A/B1-194[»]
4L62X-ray2.90A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P4-193[»]
ProteinModelPortaliQ9I1S1.
SMRiQ9I1S1. Positions 4-193.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 HTH tetR-type DNA-binding domain.UniRule annotation
Contains HTH tetR-type DNA-binding domain.SAAS annotation

Phylogenomic databases

HOGENOMiHOG000161259.
InParanoidiQ9I1S1.
KOiK16137.
OMAiQGKCLAV.
OrthoDBiEOG60KN30.
PhylomeDBiQ9I1S1.

Family and domain databases

Gene3Di1.10.357.10. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR001647. HTH_TetR.
IPR015893. Tet_transcr_reg_TetR-like_C.
IPR011075. Tet_transcr_reg_TetR-rel_C.
[Graphical view]
PfamiPF00440. TetR_N. 1 hit.
[Graphical view]
PRINTSiPR00455. HTHTETR.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF48498. SSF48498. 1 hit.
PROSITEiPS50977. HTH_TETR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9I1S1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTSYDDTRQ HLLDTGYRIM AVKGFSGVGL NEILQSAGVP KGSFYHYFKS
60 70 80 90 100
KEQFGQALLE DYFRVYLADM DQRFSAPGLN ARERLMSYWQ KWLDNACPPC
110 120 130 140 150
DEQRCLVVKL SAEVADLSES MRITLRDGSD GIIERLVGCL GQGRDDGSLA
160 170 180 190
PCDARHMASA LYQLWLGASL LSKLHRSPGP LETAMQTTRS LLEI
Length:194
Mass (Da):21,747
Last modified:March 1, 2001 - v1
Checksum:i41E57F696C5D8303
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG05584.1.
PIRiA83371.
RefSeqiNP_250886.1. NC_002516.2.

Genome annotation databases

EnsemblBacteriaiAAG05584; AAG05584; PA2196.
GeneIDi881967.
KEGGipae:PA2196.
PATRICi19838840. VBIPseAer58763_2300.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG05584.1.
PIRiA83371.
RefSeqiNP_250886.1. NC_002516.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3RD3X-ray2.40A/B1-194[»]
4L62X-ray2.90A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P4-193[»]
ProteinModelPortaliQ9I1S1.
SMRiQ9I1S1. Positions 4-193.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi208964.PA2196.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG05584; AAG05584; PA2196.
GeneIDi881967.
KEGGipae:PA2196.
PATRICi19838840. VBIPseAer58763_2300.

Organism-specific databases

PseudoCAPiPA2196.

Phylogenomic databases

HOGENOMiHOG000161259.
InParanoidiQ9I1S1.
KOiK16137.
OMAiQGKCLAV.
OrthoDBiEOG60KN30.
PhylomeDBiQ9I1S1.

Family and domain databases

Gene3Di1.10.357.10. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR001647. HTH_TetR.
IPR015893. Tet_transcr_reg_TetR-like_C.
IPR011075. Tet_transcr_reg_TetR-rel_C.
[Graphical view]
PfamiPF00440. TetR_N. 1 hit.
[Graphical view]
PRINTSiPR00455. HTHTETR.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF48498. SSF48498. 1 hit.
PROSITEiPS50977. HTH_TETR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228Imported.
  2. "Structure of Pseudomonas aeruginosa transcriptional regulator PA2196."
    Choe J., Kang Y.
    Submitted (FEB-2011) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS), ACTIVE SITE.
  3. "Crystal structure of Pseudomonas aeruginosa transcriptional regulator PA2196 bound to its operator DNA."
    Kim Y., Kang Y., Choe J.
    Biochem. Biophys. Res. Commun. 440:317-321(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.90 ANGSTROMS) OF 4-193.

Entry informationi

Entry nameiQ9I1S1_PSEAE
AccessioniPrimary (citable) accession number: Q9I1S1
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: January 7, 2015
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.