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Q9I165 (TREA_PSEAE) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Periplasmic trehalase
EC=3.2.1.28
Alternative name(s):
Alpha,alpha-trehalase
Alpha,alpha-trehalose glucohydrolase
Gene names
Name:treA
Ordered Locus Names:PA2416
OrganismPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Taxonomic identifier208964 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length545 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system By similarity. HAMAP MF_01060

Catalytic activity

Alpha,alpha-trehalose + H2O = 2 D-glucose. HAMAP MF_01060

Subcellular location

Periplasm By similarity HAMAP MF_01060.

Sequence similarities

Belongs to the glycosyl hydrolase 37 family.

Ontologies

Keywords
   Cellular componentPeriplasm
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processcellular hyperosmotic response

Inferred from electronic annotation. Source: InterPro

trehalose catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentperiplasmic space

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionalpha,alpha-trehalase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3030 Potential
Chain31 – 545515Periplasmic trehalase HAMAP MF_01060
PRO_0000012044

Sequences

Sequence LengthMass (Da)Tools
Q9I165 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: 57790CC7AD797C4F

FASTA54561,166
        10         20         30         40         50         60 
MPDRTALPRA MLAAWVLLLL AACSQGPAPT PPASWGWQDA SGERAIAPDE AYPELFQAVQ 

        70         80         90        100        110        120 
ENRLFSDQKH FVDALPLREP ARIRADYLRE RERPGFDLRA FVGRNFEESG SVETAPPEAG 

       130        140        150        160        170        180 
ADLASHISDL WPALTRHYEQ VPAHSSLLPL PKPYVVPGGR FREVYYWDSY FTMLGLAESG 

       190        200        210        220        230        240 
QHQRVRDMLD NFAYLIDTYG HIPNGNRSYY LSRSQPPFFA YMVDLQARRE GDAAYRRYLP 

       250        260        270        280        290        300 
QLQKEYAYWM EGSAGLRPNE ARLHVVKLAD GSLLNRYWDN RDTPRQESFL EDRATAARAP 

       310        320        330        340        350        360 
QRPAGEVYRD LRAGAESGWD FSSRWLDDGR ELASIRTTAI VPVDLNALLY HLERIIAKAC 

       370        380        390        400        410        420 
ASSALKACEQ GYGARAEKRR QAIEDHLWHP AGYYADYDWQ RRRPIERINA ASLFPLFTGL 

       430        440        450        460        470        480 
ASAERAGRTA DSVAAQLLRP GGLATTTRAS GQQWDEPNGW APLQWVAVQG LRAYGRDALA 

       490        500        510        520        530        540 
EDIGRRFLAQ VQQVYDREGK LVEKYDISGN QGGGGGGEYP LQDGFGWSNG VTLQLLRLYG 


PGAGR

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE004091 Genomic DNA. Translation: AAG05804.1.
PIRH83342.
RefSeqNP_251106.1. NC_002516.2.

3D structure databases

ProteinModelPortalQ9I165.
SMRQ9I165. Positions 47-542.
ModBaseSearch...

Protein family/group databases

CAZyGH37. Glycoside Hydrolase Family 37.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID882861.
GenomeReviewsGene locus PA2416 in contig AE004091_GR.
KEGGpae:PA2416.
NMPDRfig|208964.1.peg.2416.
PATRIC19839293. VBIPseAer58763_2526.

Organism-specific databases

PseudoCAPPA2416.

Phylogenomic databases

HOGENOMHBG485982.
OMANRYWDAS.
ProtClustDBPRK13272.

Enzyme and pathway databases

BioCycPAER208964:PA2416-MONOMER.

Family and domain databases

HAMAPMF_01060. Peripl_trehalase.
[Tree]
InterProIPR008928. 6-hairpin_glycosidase-like.
IPR001661. Glyco_hydro_37.
IPR018232. Glyco_hydro_37_CS.
IPR023720. Trehalase_periplasmic.
[Graphical view]
KOK01194.
PANTHERPTHR23403. Glyco_hydro_37. 1 hit.
PfamPF01204. Trehalase. 1 hit.
[Graphical view]
PRINTSPR00744. GLHYDRLASE37.
SUPFAMSSF48208. Glyco_trans_6hp. 1 hit.
PROSITEPS00927. TREHALASE_1. 1 hit.
PS00928. TREHALASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTREA_PSEAE
AccessionPrimary (citable) accession number: Q9I165
Entry history
Integrated into UniProtKB/Swiss-Prot: July 3, 2003
Last sequence update: March 1, 2001
Last modified: January 25, 2012
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

SIMILARITY comments

Index of protein domains and families

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