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Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-lysyl-[protein].UniRule annotation
L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-arginyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

BioCyciPAER208964:G1FZ6-2657-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
Alternative name(s):
L/F-transferaseUniRule annotation
LeucyltransferaseUniRule annotation
PhenyalanyltransferaseUniRule annotation
Gene namesi
Name:aatUniRule annotation
Ordered Locus Names:PA2617
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA2617

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002072341 – 226Leucyl/phenylalanyl-tRNA--protein transferaseAdd BLAST226

Proteomic databases

PaxDbiQ9I0M1

Interactioni

Protein-protein interaction databases

STRINGi208964.PA2617

Structurei

3D structure databases

ProteinModelPortaliQ9I0M1
SMRiQ9I0M1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108R4Z Bacteria
COG2360 LUCA
HOGENOMiHOG000102325
InParanoidiQ9I0M1
KOiK00684
OMAiYRQGIFP
PhylomeDBiQ9I0M1

Family and domain databases

HAMAPiMF_00688 Leu_Phe_trans, 1 hit
InterProiView protein in InterPro
IPR016181 Acyl_CoA_acyltransferase
IPR004616 Leu/Phe-tRNA_Trfase
PANTHERiPTHR30098 PTHR30098, 1 hit
PfamiView protein in Pfam
PF03588 Leu_Phe_trans, 1 hit
SUPFAMiSSF55729 SSF55729, 1 hit
TIGRFAMsiTIGR00667 aat, 1 hit

Sequencei

Sequence statusi: Complete.

Q9I0M1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLTWLSRTDF DFPPLDKALQ EPNGLLAAGG DLNPQRLVAA YRHGCFPWYQ
60 70 80 90 100
DGQPILWWSP DPRTVLFPDE LHVSRSLAKC LRQQRFEVTF NRDFRAVIQA
110 120 130 140 150
CAAPRNYADG TWITTPMQLA YQELHLRGIA HSVEVWQERQ LVGGLYGLAM
160 170 180 190 200
GRLFFGESMF SRADNASKVG FVTLVRHLRD AGFVLIDCQM PTRHLHSLGA
210 220
RAISRGEFAD YLQRYRDQPP TGDLDF
Length:226
Mass (Da):25,826
Last modified:March 1, 2001 - v1
Checksum:i04736F579000C2A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA Translation: AAG06005.1
PIRiG83318
RefSeqiNP_251307.1, NC_002516.2
WP_003113368.1, NC_002516.2

Genome annotation databases

EnsemblBacteriaiAAG06005; AAG06005; PA2617
GeneIDi882323
KEGGipae:PA2617
PATRICifig|208964.12.peg.2739

Similar proteinsi

Entry informationi

Entry nameiLFTR_PSEAE
AccessioniPrimary (citable) accession number: Q9I0M1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 25, 2003
Last sequence update: March 1, 2001
Last modified: May 23, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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