Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Cobalt-precorrin-5B C(1)-methyltransferase

Gene

cbiD

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.UniRule annotation

Catalytic activityi

Cobalt-precorrin-5B + S-adenosyl-L-methionine = cobalt-precorrin-6A + S-adenosyl-L-homocysteine.UniRule annotation

Pathwayi: adenosylcobalamin biosynthesis

This protein is involved in step 6 of the subpathway that synthesizes cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route).UniRule annotation
Proteins known to be involved in the 10 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. no protein annotated in this organism
  3. no protein annotated in this organism
  4. no protein annotated in this organism
  5. no protein annotated in this organism
  6. Cobalt-precorrin-5B C(1)-methyltransferase (cbiD)
  7. no protein annotated in this organism
  8. no protein annotated in this organism
  9. no protein annotated in this organism
  10. no protein annotated in this organism
This subpathway is part of the pathway adenosylcobalamin biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route), the pathway adenosylcobalamin biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processCobalamin biosynthesis
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciPAER208964:G1FZ6-2958-MONOMER
UniPathwayiUPA00148; UER00227

Names & Taxonomyi

Protein namesi
Recommended name:
Cobalt-precorrin-5B C(1)-methyltransferaseUniRule annotation (EC:2.1.1.195UniRule annotation)
Alternative name(s):
Cobalt-precorrin-6A synthaseUniRule annotation
Gene namesi
Name:cbiDUniRule annotation
Ordered Locus Names:PA2908
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA2908

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001416781 – 366Cobalt-precorrin-5B C(1)-methyltransferaseAdd BLAST366

Proteomic databases

PaxDbiQ9HZT9

Interactioni

Protein-protein interaction databases

STRINGi208964.PA2908

Structurei

3D structure databases

ProteinModelPortaliQ9HZT9
SMRiQ9HZT9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CbiD family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105EE8 Bacteria
COG1903 LUCA
HOGENOMiHOG000009126
InParanoidiQ9HZT9
KOiK02188
OMAiGGIFHTH
PhylomeDBiQ9HZT9

Family and domain databases

Gene3Di3.30.2110.10, 1 hit
HAMAPiMF_00787 CbiD, 1 hit
InterProiView protein in InterPro
IPR002748 CbiD
IPR036074 CbiD_sf
PANTHERiPTHR35863 PTHR35863, 1 hit
PfamiView protein in Pfam
PF01888 CbiD, 1 hit
PIRSFiPIRSF026782 CbiD, 1 hit
SUPFAMiSSF111342 SSF111342, 1 hit
TIGRFAMsiTIGR00312 cbiD, 1 hit

Sequencei

Sequence statusi: Complete.

Q9HZT9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MREETPEQPA PLRSGYTTGS CATATSLAAA RLLLGGTISD AVQIVLPKGQ
60 70 80 90 100
QVLMRLEFCR AWENGAEAGT LKDAGDDPDV THGALVFARV RLSAEPGVRF
110 120 130 140 150
HAGPGVGTVT RPGLTLAVGE PAINPVPRQM IERHLAQLAA ERGYAGGFEV
160 170 180 190 200
AIGVEGGAEL ALKTMNPRLG ILGGLSILGT SGIVRPFSCS AYIASIHQGI
210 220 230 240 250
DVARANGVRH IAACTGNASE DAMRRRYALP EIALIEMGDF AGAVLKHLRR
260 270 280 290 300
APVEKLSLCG GFGKISKLAG GHLDLHSRHS SIDLPQLAGW AAALGASTAL
310 320 330 340 350
QDSMRAANTS QQALAQAHAE GVALGDAVCA HALRFARGIV PTEVALEVFA
360
IDRQGNLVGQ ACEERR
Length:366
Mass (Da):38,146
Last modified:March 1, 2001 - v1
Checksum:i3DB271F6AB557115
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA Translation: AAG06296.1
PIRiF83281
RefSeqiNP_251598.1, NC_002516.2
WP_003114022.1, NC_002516.2

Genome annotation databases

EnsemblBacteriaiAAG06296; AAG06296; PA2908
GeneIDi882679
KEGGipae:PA2908
PATRICifig|208964.12.peg.3049

Similar proteinsi

Entry informationi

Entry nameiCBID_PSEAE
AccessioniPrimary (citable) accession number: Q9HZT9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: March 1, 2001
Last modified: March 28, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health