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Protein

Glucokinase

Gene

glk

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-glucose = ADP + D-glucose 6-phosphate.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi16 – 216ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. glucokinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
GlucokinaseUniRule annotation (EC:2.7.1.2UniRule annotation)
Alternative name(s):
Glucose kinaseUniRule annotation
Gene namesi
Name:glkUniRule annotation
Ordered Locus Names:PA3193
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000002438: Chromosome

Organism-specific databases

PseudoCAPiPA3193.

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 331331GlucokinasePRO_0000215133Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi208964.PA3193.

Structurei

3D structure databases

ProteinModelPortaliQ9HZ46.
SMRiQ9HZ46. Positions 13-327.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the bacterial glucokinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0837.
HOGENOMiHOG000274469.
InParanoidiQ9HZ46.
KOiK00845.
OMAiGHADFAP.
OrthoDBiEOG64BQ47.
PhylomeDBiQ9HZ46.

Family and domain databases

HAMAPiMF_00524. Glucokinase.
InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00749. glk. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9HZ46-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNDNKRSAG GLGLVGDIGG TNARFALWRG QRLESIEVLA CADYPRPELA
60 70 80 90 100
VRDYLARIGE SVANIDSVCL ACAGPVGAAD FRFTNNHWVI NRAAFREELG
110 120 130 140 150
LDHLLLVNDF STMAWAASRL GADELVQVRA GSAQADRARL IIGPGTGLGV
160 170 180 190 200
GSLLPLGGGR WEVLPCEGGH VDLPVTSPRD FALWQGLQAR YGHVSAERAL
210 220 230 240 250
SGNGLLALYE ISCALDGVAV RASSAAEVGA LAMAGDAQAD AVLEHFFLWL
260 270 280 290 300
ARVAGNAVLT VGALGGVYIT GGIVPRFLER FIASGFAEAF ASRGKTSGAY
310 320 330
LQDVPVWVMT AEHPGLLGAG VALQQALDAE G
Length:331
Mass (Da):34,606
Last modified:March 1, 2001 - v1
Checksum:i321718790B5130D1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG06581.1.
PIRiF83246.
RefSeqiNP_251883.1. NC_002516.2.

Genome annotation databases

EnsemblBacteriaiAAG06581; AAG06581; PA3193.
GeneIDi882908.
KEGGipae:PA3193.
PATRICi19840957. VBIPseAer58763_3339.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG06581.1.
PIRiF83246.
RefSeqiNP_251883.1. NC_002516.2.

3D structure databases

ProteinModelPortaliQ9HZ46.
SMRiQ9HZ46. Positions 13-327.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi208964.PA3193.

Protocols and materials databases

DNASUi882908.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG06581; AAG06581; PA3193.
GeneIDi882908.
KEGGipae:PA3193.
PATRICi19840957. VBIPseAer58763_3339.

Organism-specific databases

PseudoCAPiPA3193.

Phylogenomic databases

eggNOGiCOG0837.
HOGENOMiHOG000274469.
InParanoidiQ9HZ46.
KOiK00845.
OMAiGHADFAP.
OrthoDBiEOG64BQ47.
PhylomeDBiQ9HZ46.

Family and domain databases

HAMAPiMF_00524. Glucokinase.
InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00749. glk. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.

Entry informationi

Entry nameiGLK_PSEAE
AccessioniPrimary (citable) accession number: Q9HZ46
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: March 1, 2001
Last modified: January 7, 2015
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.