Q9HZ23 (Q9HZ23_PSEAE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
CyaB EMBL AAG06605.1

Gene names

Name:	cyaB EMBL AAG06605.1
Ordered Locus Names:	PA3217

Organism

Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) [Reference proteome] [HAMAP] EMBL AAG06605.1

Taxonomic identifier

208964 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › Pseudomonas aeruginosa group › Pseudomonas aeruginosa

Protein attributes

Sequence length	463 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 3R5G Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cyclic nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro intracellular signal transduction Inferred from electronic annotation. Source: InterPro
Molecular_function	phosphorus-oxygen lyase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9HZ23 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: FE4B035F2C508EDB	FASTA	463	51,404
	10 20 30 40 50 60 MKPTLPDRSP TSRSVASMRE YYSRVLAYIA CGASIAAGTY TQYFSYGILW MVPYALLYPH 70 80 90 100 110 120 LAYHLGQRFR QHDPRKVTRA LLAVDAVHCG LGMALLGFSV VPSLMFLLVL SFTALVIGGL 130 140 150 160 170 180 RLLGMALLVS ASSALLVAVL VAPPLLGNTP VEVAAVSILF CGLYICITAF FGHQQGLRLA 190 200 210 220 230 240 QVRQEIAREQ EKAARLARNL AKYLSPQVWE MIFSGKKSVR LETQRKKLTV FFSDIRGFTE 250 260 270 280 290 300 LSEELEAEAL TDLLNNYLNE MSKIALKYGG TIDKFVGDCV MVFFGDPSTQ GAKKDAVAAV 310 320 330 340 350 360 SMGIAMRKHM KVLRQQWRAQ GITKPLEIRM GINTGYCTVG NFGADTRMDY TIIGREVNLA 370 380 390 400 410 420 SRLESASEAG EILISHETYS LIKDVIMCRD KGQIAVKGFS RPVQIYQVVD SRRDLGAAPS 430 440 450 460 YVEHELPGFS MYLDTNNIQN YDKERVIQAL QQAAERLRDK VIL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen." Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P., Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M., Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y., Brody L.L., Coulter S.N., Folger K.R. , Kas A., Larbig K., Lim R.M., Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J., Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V. Nature 406:959-964(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.
[2]	"Crystal structure and regulation mechanisms of the CyaB adenylyl cyclase from the human pathogen Pseudomonas aeruginosa." Topal H., Fulcher N.B., Bitterman J., Salazar E., Buck J., Levin L.R., Cann M.J., Wolfgang M.C., Steegborn C. J. Mol. Biol. 416:271-286(2012) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS) OF 220-416.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE004091 Genomic DNA. Translation: AAG06605.1.

PIR

E83242.

RefSeq

NP_251907.1. NC_002516.2.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3R5G	X-ray	1.50	A/B	220-416	[»]

HSSP

HSSP built from PDB template 1AZS based on UniProtKB P26769.

ProteinModelPortal

Q9HZ23.

SMR

Q9HZ23. Positions 221-416.

ModBase

Search...

Protein-protein interaction databases

STRING

208964.PA3217.

Protocols and materials databases

DNASU

882555.

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

882555.

KEGG

pae:PA3217.

PATRIC

19841007. VBIPseAer58763_3364.

Organism-specific databases

PseudoCAP

PA3217.

Phylogenomic databases

HOGENOM

HOG000225757.

KO

K05345.

OMA

QSIALSH.

ProtClustDB

CLSK867825.

Family and domain databases

Gene3D

3.30.70.1230. 1 hit.

InterPro

IPR001054. A/G_cyclase.
IPR007894. MASE2.
[Graphical view]

Pfam

PF00211. Guanylate_cyc. 1 hit.
PF05230. MASE2. 1 hit.
[Graphical view]

SMART

SM00044. CYCc. 1 hit.
[Graphical view]

SUPFAM

SSF55073. A/G_cyclase. 1 hit.

PROSITE

PS50125. GUANYLATE_CYCLASE_2. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q9HZ23_PSEAE

Accession

Primary (citable) accession number: Q9HZ23

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2001
Last sequence update:	March 1, 2001
Last modified:	May 1, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)