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Q9HZ23

- Q9HZ23_PSEAE

UniProt

Q9HZ23 - Q9HZ23_PSEAE

Protein
Submitted name:

CyaB

Gene

cyaB

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 72 (01 Oct 2014)
      Sequence version 1 (01 Mar 2001)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. adenylate cyclase activity Source: PseudoCAP

    GO - Biological processi

    1. cAMP biosynthetic process Source: PseudoCAP
    2. intracellular signal transduction Source: InterPro
    3. pathogenesis Source: PseudoCAP

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    CyaBImported
    Gene namesi
    Name:cyaBImported
    Ordered Locus Names:PA3217Imported
    OrganismiPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)Imported
    Taxonomic identifieri208964 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
    ProteomesiUP000002438: Chromosome

    Organism-specific databases

    PseudoCAPiPA3217.

    Interactioni

    Protein-protein interaction databases

    STRINGi208964.PA3217.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3R5GX-ray1.50A/B220-416[»]
    ProteinModelPortaliQ9HZ23.
    SMRiQ9HZ23. Positions 221-416.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000225757.
    KOiK05345.
    OMAiGQITVKG.
    OrthoDBiEOG690M9K.
    PhylomeDBiQ9HZ23.

    Family and domain databases

    Gene3Di3.30.70.1230. 1 hit.
    InterProiIPR001054. A/G_cyclase.
    IPR007894. MASE2.
    [Graphical view]
    PfamiPF00211. Guanylate_cyc. 1 hit.
    PF05230. MASE2. 1 hit.
    [Graphical view]
    SMARTiSM00044. CYCc. 1 hit.
    [Graphical view]
    SUPFAMiSSF55073. SSF55073. 1 hit.
    PROSITEiPS50125. GUANYLATE_CYCLASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9HZ23-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKPTLPDRSP TSRSVASMRE YYSRVLAYIA CGASIAAGTY TQYFSYGILW    50
    MVPYALLYPH LAYHLGQRFR QHDPRKVTRA LLAVDAVHCG LGMALLGFSV 100
    VPSLMFLLVL SFTALVIGGL RLLGMALLVS ASSALLVAVL VAPPLLGNTP 150
    VEVAAVSILF CGLYICITAF FGHQQGLRLA QVRQEIAREQ EKAARLARNL 200
    AKYLSPQVWE MIFSGKKSVR LETQRKKLTV FFSDIRGFTE LSEELEAEAL 250
    TDLLNNYLNE MSKIALKYGG TIDKFVGDCV MVFFGDPSTQ GAKKDAVAAV 300
    SMGIAMRKHM KVLRQQWRAQ GITKPLEIRM GINTGYCTVG NFGADTRMDY 350
    TIIGREVNLA SRLESASEAG EILISHETYS LIKDVIMCRD KGQIAVKGFS 400
    RPVQIYQVVD SRRDLGAAPS YVEHELPGFS MYLDTNNIQN YDKERVIQAL 450
    QQAAERLRDK VIL 463
    Length:463
    Mass (Da):51,404
    Last modified:March 1, 2001 - v1
    Checksum:iFE4B035F2C508EDB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE004091 Genomic DNA. Translation: AAG06605.1.
    PIRiE83242.
    RefSeqiNP_251907.1. NC_002516.2.

    Genome annotation databases

    EnsemblBacteriaiAAG06605; AAG06605; PA3217.
    GeneIDi882555.
    KEGGipae:PA3217.
    PATRICi19841007. VBIPseAer58763_3364.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE004091 Genomic DNA. Translation: AAG06605.1 .
    PIRi E83242.
    RefSeqi NP_251907.1. NC_002516.2.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3R5G X-ray 1.50 A/B 220-416 [» ]
    ProteinModelPortali Q9HZ23.
    SMRi Q9HZ23. Positions 221-416.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 208964.PA3217.

    Protocols and materials databases

    DNASUi 882555.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAG06605 ; AAG06605 ; PA3217 .
    GeneIDi 882555.
    KEGGi pae:PA3217.
    PATRICi 19841007. VBIPseAer58763_3364.

    Organism-specific databases

    PseudoCAPi PA3217.

    Phylogenomic databases

    HOGENOMi HOG000225757.
    KOi K05345.
    OMAi GQITVKG.
    OrthoDBi EOG690M9K.
    PhylomeDBi Q9HZ23.

    Family and domain databases

    Gene3Di 3.30.70.1230. 1 hit.
    InterProi IPR001054. A/G_cyclase.
    IPR007894. MASE2.
    [Graphical view ]
    Pfami PF00211. Guanylate_cyc. 1 hit.
    PF05230. MASE2. 1 hit.
    [Graphical view ]
    SMARTi SM00044. CYCc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55073. SSF55073. 1 hit.
    PROSITEi PS50125. GUANYLATE_CYCLASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228Imported.
    2. "Crystal structure and regulation mechanisms of the CyaB adenylyl cyclase from the human pathogen Pseudomonas aeruginosa."
      Topal H., Fulcher N.B., Bitterman J., Salazar E., Buck J., Levin L.R., Cann M.J., Wolfgang M.C., Steegborn C.
      J. Mol. Biol. 416:271-286(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS) OF 220-416.

    Entry informationi

    Entry nameiQ9HZ23_PSEAE
    AccessioniPrimary (citable) accession number: Q9HZ23
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2001
    Last sequence update: March 1, 2001
    Last modified: October 1, 2014
    This is version 72 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3