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Q9HZ23

- Q9HZ23_PSEAE

UniProt

Q9HZ23 - Q9HZ23_PSEAE

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Protein
Submitted name:

CyaB

Gene

cyaB

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. adenylate cyclase activity Source: PseudoCAP

GO - Biological processi

  1. cAMP biosynthetic process Source: PseudoCAP
  2. intracellular signal transduction Source: InterPro
  3. pathogenesis Source: PseudoCAP
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
CyaBImported
Gene namesi
Name:cyaBImported
Ordered Locus Names:PA3217Imported
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)Imported
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000002438: Chromosome

Organism-specific databases

PseudoCAPiPA3217.

Interactioni

Protein-protein interaction databases

STRINGi208964.PA3217.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3R5GX-ray1.50A/B220-416[»]
ProteinModelPortaliQ9HZ23.
SMRiQ9HZ23. Positions 221-416.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000225757.
InParanoidiQ9HZ23.
KOiK05345.
OMAiGQITVKG.
OrthoDBiEOG690M9K.
PhylomeDBiQ9HZ23.

Family and domain databases

Gene3Di3.30.70.1230. 1 hit.
InterProiIPR001054. A/G_cyclase.
IPR007894. MASE2.
IPR029787. Nucleotide_cyclase.
[Graphical view]
PfamiPF00211. Guanylate_cyc. 1 hit.
PF05230. MASE2. 1 hit.
[Graphical view]
SMARTiSM00044. CYCc. 1 hit.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 1 hit.
PROSITEiPS50125. GUANYLATE_CYCLASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9HZ23-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKPTLPDRSP TSRSVASMRE YYSRVLAYIA CGASIAAGTY TQYFSYGILW
60 70 80 90 100
MVPYALLYPH LAYHLGQRFR QHDPRKVTRA LLAVDAVHCG LGMALLGFSV
110 120 130 140 150
VPSLMFLLVL SFTALVIGGL RLLGMALLVS ASSALLVAVL VAPPLLGNTP
160 170 180 190 200
VEVAAVSILF CGLYICITAF FGHQQGLRLA QVRQEIAREQ EKAARLARNL
210 220 230 240 250
AKYLSPQVWE MIFSGKKSVR LETQRKKLTV FFSDIRGFTE LSEELEAEAL
260 270 280 290 300
TDLLNNYLNE MSKIALKYGG TIDKFVGDCV MVFFGDPSTQ GAKKDAVAAV
310 320 330 340 350
SMGIAMRKHM KVLRQQWRAQ GITKPLEIRM GINTGYCTVG NFGADTRMDY
360 370 380 390 400
TIIGREVNLA SRLESASEAG EILISHETYS LIKDVIMCRD KGQIAVKGFS
410 420 430 440 450
RPVQIYQVVD SRRDLGAAPS YVEHELPGFS MYLDTNNIQN YDKERVIQAL
460
QQAAERLRDK VIL
Length:463
Mass (Da):51,404
Last modified:March 1, 2001 - v1
Checksum:iFE4B035F2C508EDB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG06605.1.
PIRiE83242.
RefSeqiNP_251907.1. NC_002516.2.

Genome annotation databases

EnsemblBacteriaiAAG06605; AAG06605; PA3217.
GeneIDi882555.
KEGGipae:PA3217.
PATRICi19841007. VBIPseAer58763_3364.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG06605.1 .
PIRi E83242.
RefSeqi NP_251907.1. NC_002516.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3R5G X-ray 1.50 A/B 220-416 [» ]
ProteinModelPortali Q9HZ23.
SMRi Q9HZ23. Positions 221-416.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 208964.PA3217.

Protocols and materials databases

DNASUi 882555.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAG06605 ; AAG06605 ; PA3217 .
GeneIDi 882555.
KEGGi pae:PA3217.
PATRICi 19841007. VBIPseAer58763_3364.

Organism-specific databases

PseudoCAPi PA3217.

Phylogenomic databases

HOGENOMi HOG000225757.
InParanoidi Q9HZ23.
KOi K05345.
OMAi GQITVKG.
OrthoDBi EOG690M9K.
PhylomeDBi Q9HZ23.

Family and domain databases

Gene3Di 3.30.70.1230. 1 hit.
InterProi IPR001054. A/G_cyclase.
IPR007894. MASE2.
IPR029787. Nucleotide_cyclase.
[Graphical view ]
Pfami PF00211. Guanylate_cyc. 1 hit.
PF05230. MASE2. 1 hit.
[Graphical view ]
SMARTi SM00044. CYCc. 1 hit.
[Graphical view ]
SUPFAMi SSF55073. SSF55073. 1 hit.
PROSITEi PS50125. GUANYLATE_CYCLASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228Imported.
  2. "Crystal structure and regulation mechanisms of the CyaB adenylyl cyclase from the human pathogen Pseudomonas aeruginosa."
    Topal H., Fulcher N.B., Bitterman J., Salazar E., Buck J., Levin L.R., Cann M.J., Wolfgang M.C., Steegborn C.
    J. Mol. Biol. 416:271-286(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS) OF 220-416.

Entry informationi

Entry nameiQ9HZ23_PSEAE
AccessioniPrimary (citable) accession number: Q9HZ23
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: October 29, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteomeImported

External Data

Dasty 3