Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable D-serine dehydratase

Gene

dsdA

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-serine = pyruvate + NH3.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Ligandi

Pyridoxal phosphate

Names & Taxonomyi

Protein namesi
Recommended name:
Probable D-serine dehydrataseUniRule annotation (EC:4.3.1.18UniRule annotation)
Alternative name(s):
D-serine deaminaseUniRule annotation
Short name:
DSDUniRule annotation
Gene namesi
Name:dsdAUniRule annotation
Ordered Locus Names:PA3357
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA3357.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001856181 – 448Probable D-serine dehydrataseAdd BLAST448

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei119N6-(pyridoxal phosphate)lysineUniRule annotation1

Proteomic databases

PaxDbiQ9HYN9.

Interactioni

Protein-protein interaction databases

STRINGi208964.PA3357.

Structurei

3D structure databases

ProteinModelPortaliQ9HYN9.
SMRiQ9HYN9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the serine/threonine dehydratase family. DsdA subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105BZC. Bacteria.
COG3048. LUCA.
HOGENOMiHOG000218072.
InParanoidiQ9HYN9.
KOiK01753.
OMAiESDPNCF.
PhylomeDBiQ9HYN9.

Family and domain databases

HAMAPiMF_01030. D_Ser_dehydrat. 1 hit.
InterProiIPR011780. D_Ser_am_lyase.
IPR000634. Ser/Thr_deHydtase_PyrdxlP-BS.
IPR001926. TrpB-like_PLP-dep.
[Graphical view]
PANTHERiPTHR10314:SF9. PTHR10314:SF9. 2 hits.
PfamiPF00291. PALP. 1 hit.
[Graphical view]
SUPFAMiSSF53686. SSF53686. 1 hit.
TIGRFAMsiTIGR02035. D_Ser_am_lyase. 1 hit.
PROSITEiPS00165. DEHYDRATASE_SER_THR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9HYN9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MILGTPKADW LAEFPRLADL IALRPSEWFN PAIAPSAEAL ADVGLGAADV
60 70 80 90 100
ADASARLQRF APLIARLFPE TAASGGIIES DLVEVATFHD ALRQHYAAEL
110 120 130 140 150
PGRLWLKRDS HLPISGSIKA RGGIYEVLAH AERLALEHGL VGLDDDYSRL
160 170 180 190 200
AEADCRAFFA RHRIAVGSTG NLGLSIGIIG AALGFQASVH MSADARQWKK
210 220 230 240 250
DKLRAHGVTV VEYASDYSVA VEQGRREAAG DPYTHFVDDE NSRDLFLGYA
260 270 280 290 300
VAAERLRGQL DAAGIRVDSE HPLFVHLPCG VGGGPGGVAF GLKLAFGDAV
310 320 330 340 350
HCLFAEPTHS PCMFLGVYTG RHEQVSVQDF GIDNRTAADG LAVGRPSGFV
360 370 380 390 400
GRAMQRLLDG YYTVDDDELF RLLALLERSQ GIRLEPSALA GATGIARVTR
410 420 430 440
EPQGYRERMG LTSARLANAT HLVWATGGGM VPETEMRAYL ERGRSLLD
Length:448
Mass (Da):48,219
Last modified:March 1, 2001 - v1
Checksum:iCA32EFE786EDEB48
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG06745.1.
PIRiD83225.
RefSeqiNP_252047.1. NC_002516.2.
WP_003113132.1. NC_002516.2.

Genome annotation databases

EnsemblBacteriaiAAG06745; AAG06745; PA3357.
GeneIDi882524.
KEGGipae:PA3357.
PATRICi19841315. VBIPseAer58763_3516.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG06745.1.
PIRiD83225.
RefSeqiNP_252047.1. NC_002516.2.
WP_003113132.1. NC_002516.2.

3D structure databases

ProteinModelPortaliQ9HYN9.
SMRiQ9HYN9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi208964.PA3357.

Proteomic databases

PaxDbiQ9HYN9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG06745; AAG06745; PA3357.
GeneIDi882524.
KEGGipae:PA3357.
PATRICi19841315. VBIPseAer58763_3516.

Organism-specific databases

PseudoCAPiPA3357.

Phylogenomic databases

eggNOGiENOG4105BZC. Bacteria.
COG3048. LUCA.
HOGENOMiHOG000218072.
InParanoidiQ9HYN9.
KOiK01753.
OMAiESDPNCF.
PhylomeDBiQ9HYN9.

Family and domain databases

HAMAPiMF_01030. D_Ser_dehydrat. 1 hit.
InterProiIPR011780. D_Ser_am_lyase.
IPR000634. Ser/Thr_deHydtase_PyrdxlP-BS.
IPR001926. TrpB-like_PLP-dep.
[Graphical view]
PANTHERiPTHR10314:SF9. PTHR10314:SF9. 2 hits.
PfamiPF00291. PALP. 1 hit.
[Graphical view]
SUPFAMiSSF53686. SSF53686. 1 hit.
TIGRFAMsiTIGR02035. D_Ser_am_lyase. 1 hit.
PROSITEiPS00165. DEHYDRATASE_SER_THR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSDHD_PSEAE
AccessioniPrimary (citable) accession number: Q9HYN9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 19, 2002
Last sequence update: March 1, 2001
Last modified: November 2, 2016
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.