Reviewed, UniProtKB/Swiss-Prot Q9HYF4 (MQO1_PSEAE)

Names and origin

Protein names

Recommended name:
    Probable malate:quinone oxidoreductase 1
    EC=1.1.99.16
Alternative name(s):
    Malate dehydrogenase [acceptor] 1
    MQO 1

Gene names

Name:	mqo1
Synonyms:	mqoA
Ordered Locus Names:	PA3452

Organism

Pseudomonas aeruginosa [Complete proteome] [HAMAP]

Taxonomic identifier

287 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	523 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(S)-malate + acceptor = oxaloacetate + reduced acceptor. HAMAP MF_00212
Cofactor	FAD By similarity.
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW tricarboxylic acid cycle Inferred from electronic annotation. Source: HAMAP
Molecular function	malate dehydrogenase (acceptor) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 523	523	Probable malate:quinone oxidoreductase 1 HAMAP MF_00212		PRO_0000128729

Sequences

	Sequence		Length	Mass (Da)
	Q9HYF4-1 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 03E90117F88890B3	FASTA	523	57,210
	10 20 30 40 50 60 MKKILLMLLC VSVLGCSKNS VESEKPVDVL LIGGGIMSAT LGTYLNELEP GWTIEMVERL 70 80 90 100 110 120 DKVAEESSNG WNNAGTGHSA FCELNYTSEA ADGSMDISKA VAINENFEIS KQFWAYQVDR 130 140 150 160 170 180 KVLNDPKSFI NNVPHMSFVW GDDNVAFLKK RHAALQHSSL FRGMEYSEDP EQIKQWVPLV 190 200 210 220 230 240 MEGREPGQKI AATRMSIGTD VNFGEITRQL VGSLSAKDTF KLRLQHEVRD LKRNDDNTWT 250 260 270 280 290 300 VTMADLANGD KETSVKARFV FIGAGGGALK LLQMSGIPEA EGYAGFPVGG SFLATTNPDV 310 320 330 340 350 360 VKRHLAKVYG KASVGSPPMS VPHLDTRMID GKPVLLFGPF ATFSTKFLKN GSLWDLPGSV 370 380 390 400 410 420 TSGNIGPMFN AGIDNFDLSQ YLIGQLMLSQ DDRMASLREY FPEARDEDWK LVQAGQRVQI 430 440 450 460 470 480 IKKDAEKGGV LQFGTEVVTA ADGSVAALLG ASPGASTAAP IMLSVLEKAF KDKVATPEWQ 490 500 510 520 ARLKEIVPSY GRKLNNDIEL TNSTRAWSSE RLQLIHVPVQ PEA

References

[1]

"Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen." Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P., Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M., Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y., Brody L.L., Coulter S.N., Folger K.R. , Kas A., Larbig K., Lim R.M., Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J., Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V. Nature 406:959-964(2000) [PubMed: 10984043] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE004091 Genomic DNA. Translation: AAG06840.1.
PIR	C83213.
RefSeq	NP_252142.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	879029.
GenomeReviews	Gene locus PA3452 in contig AE004091_GR.
KEGG	pae:PA3452.
NMPDR	fig|208964.1.peg.3452.
Organism-specific databases
PseudoCAP	PA3452.
CMR	Search...
Phylogenomic databases
HOGENOM	Q9HYF4.
OMA	Q9HYF4. EGYAGFP.
Enzyme and pathway databases
BioCyc	PAER208964:PA3452-MON.
BRENDA	1.1.99.16. 354.
Family and domain databases
HAMAP	MF_00212. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO1_PSEAE

Accession

Primary (citable) accession number: Q9HYF4

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 2002
Last sequence update:	March 1, 2001
Last modified:	May 5, 2009
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)