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Protein

Bacterioferritin

Gene

bfrB

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Iron-storage protein, whose ferroxidase center binds Fe2+ ions, oxidizes them by dioxygen to Fe3+, and participates in the subsequent Fe3+ oxide mineral core formation within the central cavity of the protein complex.UniRule annotation

Catalytic activityi

4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi18Iron 1Combined sources1
Metal bindingi18Iron 2Combined sources1
Metal bindingi51Iron 1Combined sources1
Metal bindingi51Iron 2Combined sources1
Metal bindingi51Iron 3Combined sources1
Metal bindingi52Iron (heme axial ligand)Combined sources1
Metal bindingi94Iron 3Combined sources1
Metal bindingi94Iron 4Combined sources1
Metal bindingi118Iron 5Combined sources1
Metal bindingi125Iron 5Combined sources1
Metal bindingi127Iron 1Combined sources1
Metal bindingi127Iron 3Combined sources1
Metal bindingi127Iron 4Combined sources1
Metal bindingi130Iron 4; via pros nitrogenCombined sources1
Metal bindingi155Iron 2; via tele nitrogenCombined sources1

GO - Molecular functioni

GO - Biological processi

  • intracellular sequestering of iron ion Source: PseudoCAP
  • iron ion transport Source: InterPro

Keywordsi

Biological processIron storageUniRule annotation
LigandHemeUniRule annotationCombined sources, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
BacterioferritinUniRule annotation (EC:1.16.3.1UniRule annotation)
Gene namesi
Name:bfrBImported
Ordered Locus Names:PA3531Imported
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)Imported
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA3531.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Proteomic databases

PaxDbiQ9HY79.
PRIDEiQ9HY79.

Interactioni

Protein-protein interaction databases

STRINGi208964.PA3531.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3IS7X-ray2.10A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X1-158[»]
3IS8X-ray2.25A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X1-158[»]
3ISEX-ray2.80A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X1-158[»]
3ISFX-ray2.07A/B/C/D/E/F1-158[»]
4E6KX-ray2.00A/B/C/D/E/F1-158[»]
4TO9X-ray2.00A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X1-158[»]
4TOAX-ray1.95A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X1-158[»]
4TOBX-ray1.95A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X1-158[»]
4TOCX-ray2.25A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X1-158[»]
4TODX-ray2.05A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X1-158[»]
4TOEX-ray2.20A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X1-158[»]
4TOFX-ray1.65A/B/C/D1-158[»]
4TOGX-ray1.80A/B/C/D1-158[»]
4TOHX-ray1.80A/B/C/D1-158[»]
5D8OX-ray1.90A/B/C/D/E/F/G/H/I/J/K/L1-158[»]
5D8PX-ray2.35A/B/C/D/E/F/G/H/I/J/K/L1-158[»]
5D8QX-ray2.20A/B/C/D/E/F/G/H/I/J/K/L1-158[»]
5D8RX-ray2.50A/B/C/D/E/F/G/H/I/J/K/L1-158[»]
5D8SX-ray2.55A/B/C/D/E/F/G/H/I/J/K/L1-158[»]
5D8XX-ray1.50A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X1-158[»]
5D8YX-ray2.05A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X1-158[»]
ProteinModelPortaliQ9HY79.
SMRiQ9HY79.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9HY79.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 145Ferritin-like diironInterPro annotationAdd BLAST145

Sequence similaritiesi

Belongs to the bacterioferritin family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UQY. Bacteria.
COG2193. LUCA.
InParanoidiQ9HY79.
KOiK03594.
OMAiFLHAKMQ.
PhylomeDBiQ9HY79.

Family and domain databases

CDDicd00907. Bacterioferritin. 1 hit.
Gene3Di1.20.1260.10. 1 hit.
InterProiView protein in InterPro
IPR002024. Bacterioferritin.
IPR009040. Ferritin-like_diiron.
IPR009078. Ferritin-like_SF.
IPR012347. Ferritin-rel.
IPR008331. Ferritin_DPS_dom.
PfamiView protein in Pfam
PF00210. Ferritin. 1 hit.
PIRSFiPIRSF002560. Bacterioferritin. 1 hit.
PRINTSiPR00601. BACFERRITIN.
SUPFAMiSSF47240. SSF47240. 1 hit.
TIGRFAMsiTIGR00754. bfr. 1 hit.
PROSITEiView protein in PROSITE
PS00549. BACTERIOFERRITIN. 1 hit.
PS50905. FERRITIN_LIKE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9HY79-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKGDKKVIQH LNKILGNELI AINQYFLHSR MWNDWGLKRL GAHEYHESID
60 70 80 90 100
EMKHADKLIE RILFLEGLPN LQDLGKLLIG ENTQEMLQCD LNLELKATKD
110 120 130 140 150
LREAIVHCEQ VHDYVSRDLL KDILESEEEH IDYLETQLGL IQKVGLENYL

QSHMHEDD
Length:158
Mass (Da):18,553
Last modified:March 1, 2001 - v1
Checksum:i7639729EA8E5F3FC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG06919.1.
PIRiA83205.
RefSeqiNP_252221.1. NC_002516.2.
WP_003092078.1. NC_002516.2.

Genome annotation databases

EnsemblBacteriaiAAG06919; AAG06919; PA3531.
GeneIDi879026.
KEGGipae:PA3531.
PATRICifig|208964.12.peg.3695.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ9HY79_PSEAE
AccessioniPrimary (citable) accession number: Q9HY79
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: July 5, 2017
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported