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Q9HY23

- KDGL_PSEAE

UniProt

Q9HY23 - KDGL_PSEAE

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Protein

Diacylglycerol kinase

Gene

dgkA

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Recycling of diacylglycerol produced during the turnover of membrane phospholipid.By similarity

Catalytic activityi

ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. diacylglycerol kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. phospholipid biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Diacylglycerol kinase (EC:2.7.1.107)
Short name:
DAGK
Alternative name(s):
Diglyceride kinase
Short name:
DGK
Gene namesi
Name:dgkA
Ordered Locus Names:PA3603
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000002438: Chromosome

Organism-specific databases

PseudoCAPiPA3603.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 123123Diacylglycerol kinasePRO_0000287766Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi208964.PA3603.

Structurei

3D structure databases

ProteinModelPortaliQ9HY23.
SMRiQ9HY23. Positions 60-121.
ModBaseiSearch...
MobiDBiSearch...

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 3434CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini82 – 10120CytoplasmicSequence AnalysisAdd
BLAST

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei35 – 5521HelicalSequence AnalysisAdd
BLAST
Transmembranei61 – 8121HelicalSequence AnalysisAdd
BLAST
Transmembranei102 – 12221HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0818.
HOGENOMiHOG000014819.
InParanoidiQ9HY23.
KOiK00901.
OMAiNDSHDAH.
OrthoDBiEOG60W7XM.
PhylomeDBiQ9HY23.

Family and domain databases

InterProiIPR000829. Diacylglycerol_kinase_prok.
[Graphical view]
PfamiPF01219. DAGK_prokar. 1 hit.
[Graphical view]
PROSITEiPS01069. DAGK_PROKAR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9HY23-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSPSPFKGQT GLKRILNATG YSLAGFLAAF RGEAAFRQLV LLNVVLIPVA
60 70 80 90 100
FLLDVSRGER ALMIAVCLLA LIVELLNSAI EATVDRVSLE RHPLSKNAKD
110 120
MGSAAQFVAL TVITVTWATI LLG
Length:123
Mass (Da):13,138
Last modified:March 1, 2001 - v1
Checksum:i1B8FE001E1EAE9A6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE004091 Genomic DNA. Translation: AAG06991.1.
PIRiE83196.
RefSeqiNP_252293.1. NC_002516.2.

Genome annotation databases

EnsemblBacteriaiAAG06991; AAG06991; PA3603.
GeneIDi880149.
KEGGipae:PA3603.
PATRICi19841825. VBIPseAer58763_3770.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE004091 Genomic DNA. Translation: AAG06991.1 .
PIRi E83196.
RefSeqi NP_252293.1. NC_002516.2.

3D structure databases

ProteinModelPortali Q9HY23.
SMRi Q9HY23. Positions 60-121.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 208964.PA3603.

Protocols and materials databases

DNASUi 880149.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAG06991 ; AAG06991 ; PA3603 .
GeneIDi 880149.
KEGGi pae:PA3603.
PATRICi 19841825. VBIPseAer58763_3770.

Organism-specific databases

PseudoCAPi PA3603.

Phylogenomic databases

eggNOGi COG0818.
HOGENOMi HOG000014819.
InParanoidi Q9HY23.
KOi K00901.
OMAi NDSHDAH.
OrthoDBi EOG60W7XM.
PhylomeDBi Q9HY23.

Family and domain databases

InterProi IPR000829. Diacylglycerol_kinase_prok.
[Graphical view ]
Pfami PF01219. DAGK_prokar. 1 hit.
[Graphical view ]
PROSITEi PS01069. DAGK_PROKAR. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.

Entry informationi

Entry nameiKDGL_PSEAE
AccessioniPrimary (citable) accession number: Q9HY23
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: March 1, 2001
Last modified: October 29, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3