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Q9HY23

- KDGL_PSEAE

UniProt

Q9HY23 - KDGL_PSEAE

Protein

Diacylglycerol kinase

Gene

dgkA

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 1 (01 Mar 2001)
      Previous versions | rss
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    Functioni

    Recycling of diacylglycerol produced during the turnover of membrane phospholipid.By similarity

    Catalytic activityi

    ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. diacylglycerol kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. phospholipid biosynthetic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Diacylglycerol kinase (EC:2.7.1.107)
    Short name:
    DAGK
    Alternative name(s):
    Diglyceride kinase
    Short name:
    DGK
    Gene namesi
    Name:dgkA
    Ordered Locus Names:PA3603
    OrganismiPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
    Taxonomic identifieri208964 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
    ProteomesiUP000002438: Chromosome

    Organism-specific databases

    PseudoCAPiPA3603.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 123123Diacylglycerol kinasePRO_0000287766Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi208964.PA3603.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9HY23.
    SMRiQ9HY23. Positions 14-121.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 3434CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini82 – 10120CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei35 – 5521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei61 – 8121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei102 – 12221HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0818.
    HOGENOMiHOG000014819.
    KOiK00901.
    OMAiNDSHDAH.
    OrthoDBiEOG60W7XM.
    PhylomeDBiQ9HY23.

    Family and domain databases

    InterProiIPR000829. Diacylglycerol_kinase_prok.
    [Graphical view]
    PfamiPF01219. DAGK_prokar. 1 hit.
    [Graphical view]
    PROSITEiPS01069. DAGK_PROKAR. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9HY23-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSPSPFKGQT GLKRILNATG YSLAGFLAAF RGEAAFRQLV LLNVVLIPVA    50
    FLLDVSRGER ALMIAVCLLA LIVELLNSAI EATVDRVSLE RHPLSKNAKD 100
    MGSAAQFVAL TVITVTWATI LLG 123
    Length:123
    Mass (Da):13,138
    Last modified:March 1, 2001 - v1
    Checksum:i1B8FE001E1EAE9A6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE004091 Genomic DNA. Translation: AAG06991.1.
    PIRiE83196.
    RefSeqiNP_252293.1. NC_002516.2.

    Genome annotation databases

    EnsemblBacteriaiAAG06991; AAG06991; PA3603.
    GeneIDi880149.
    KEGGipae:PA3603.
    PATRICi19841825. VBIPseAer58763_3770.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE004091 Genomic DNA. Translation: AAG06991.1 .
    PIRi E83196.
    RefSeqi NP_252293.1. NC_002516.2.

    3D structure databases

    ProteinModelPortali Q9HY23.
    SMRi Q9HY23. Positions 14-121.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 208964.PA3603.

    Protocols and materials databases

    DNASUi 880149.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAG06991 ; AAG06991 ; PA3603 .
    GeneIDi 880149.
    KEGGi pae:PA3603.
    PATRICi 19841825. VBIPseAer58763_3770.

    Organism-specific databases

    PseudoCAPi PA3603.

    Phylogenomic databases

    eggNOGi COG0818.
    HOGENOMi HOG000014819.
    KOi K00901.
    OMAi NDSHDAH.
    OrthoDBi EOG60W7XM.
    PhylomeDBi Q9HY23.

    Family and domain databases

    InterProi IPR000829. Diacylglycerol_kinase_prok.
    [Graphical view ]
    Pfami PF01219. DAGK_prokar. 1 hit.
    [Graphical view ]
    PROSITEi PS01069. DAGK_PROKAR. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.

    Entry informationi

    Entry nameiKDGL_PSEAE
    AccessioniPrimary (citable) accession number: Q9HY23
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 15, 2007
    Last sequence update: March 1, 2001
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3