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Protein
Submitted name:

Probable two-component response regulator

Gene

wspR

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei194Cyclic diguanosine monophosphateCombined sources1
Binding sitei198Cyclic diguanosine monophosphateCombined sources1
Binding sitei262Cyclic diguanosine monophosphateCombined sources1
Binding sitei327Cyclic diguanosine monophosphateCombined sources1
Binding sitei331Cyclic diguanosine monophosphateCombined sources1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi212 – 215Cyclic diguanosine monophosphateCombined sources4
Nucleotide bindingi241 – 245Cyclic diguanosine monophosphateCombined sources5

GO - Molecular functioni

  • diguanylate cyclase activity Source: PseudoCAP
  • identical protein binding Source: IntAct
  • nucleotide binding Source: UniProtKB-KW

GO - Biological processi

Keywordsi

LigandNucleotide-bindingCombined sources

Enzyme and pathway databases

BioCyciPAER208964:G1FZ6-3772-MONOMER

Names & Taxonomyi

Protein namesi
Submitted name:
Probable two-component response regulatorImported
Gene namesi
Name:wspRImported
Ordered Locus Names:PA3702Imported
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)Imported
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA3702

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei704-aspartylphosphatePROSITE-ProRule annotation1

Keywords - PTMi

PhosphoproteinPROSITE-ProRule annotation

Proteomic databases

PaxDbiQ9HXT9

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
itself3EBI-15694918,EBI-15694918

GO - Molecular functioni

  • identical protein binding Source: IntAct

Protein-protein interaction databases

STRINGi208964.PA3702

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3BREX-ray2.40A/B1-347[»]
3I5BX-ray2.04A/B172-347[»]
3I5CX-ray1.94A/B172-347[»]
ProteinModelPortaliQ9HXT9
SMRiQ9HXT9
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9HXT9

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 137Response regulatoryInterPro annotationAdd BLAST118
Domaini201 – 339GGDEFInterPro annotationAdd BLAST139

Phylogenomic databases

eggNOGiENOG4105BZU Bacteria
ENOG410XNMH LUCA
HOGENOMiHOG000167205
InParanoidiQ9HXT9
KOiK11444
OMAiFIHKPAS
PhylomeDBiQ9HXT9

Family and domain databases

CDDicd01949 GGDEF, 1 hit
cd00156 REC, 1 hit
InterProiView protein in InterPro
IPR011006 CheY-like_superfamily
IPR000160 GGDEF_dom
IPR029787 Nucleotide_cyclase
IPR001789 Sig_transdc_resp-reg_receiver
PfamiView protein in Pfam
PF00990 GGDEF, 1 hit
PF00072 Response_reg, 1 hit
SMARTiView protein in SMART
SM00267 GGDEF, 1 hit
SM00448 REC, 1 hit
SUPFAMiSSF52172 SSF52172, 1 hit
SSF55073 SSF55073, 1 hit
TIGRFAMsiTIGR00254 GGDEF, 1 hit
PROSITEiView protein in PROSITE
PS50887 GGDEF, 1 hit
PS50110 RESPONSE_REGULATORY, 1 hit

Sequencei

Sequence statusi: Complete.

Q9HXT9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHNPHESKTD LGAPLDGAVM VLLVDDQAMI GEAVRRSLAS EAGIDFHFCS
60 70 80 90 100
DPQQAVAVAN QIKPTVILQD LVMPGVDGLT LLAAYRGNPA TRDIPIIVLS
110 120 130 140 150
TKEEPTVKSA AFAAGANDYL VKLPDAIELV ARIRYHSRSY IALQQRDEAY
160 170 180 190 200
RALRESQQQL LETNLVLQRL MNSDGLTGLS NRRHFDEYLE MEWRRSLREQ
210 220 230 240 250
SQLSLLMIDV DYFKSYNDTF GHVAGDEALR QVAGAIREGC SRSSDLAARY
260 270 280 290 300
GGEEFAMVLP GTSPGGARLL AEKVRRTVES LQISHDQPRP GSHLTVSIGV
310 320 330 340
STLVPGGGGQ TFRVLIEMAD QALYQAKNNG RNQVGLMEQP VPPAPAG
Length:347
Mass (Da):37,887
Last modified:March 1, 2001 - v1
Checksum:iAE706D630586649E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA Translation: AAG07089.1
PIRiE83183
RefSeqiNP_252391.1, NC_002516.2
WP_003103734.1, NC_002516.2

Genome annotation databases

EnsemblBacteriaiAAG07089; AAG07089; PA3702
GeneIDi878337
KEGGipae:PA3702
PATRICifig|208964.12.peg.3873

Similar proteinsi

Entry informationi

Entry nameiQ9HXT9_PSEAE
AccessioniPrimary (citable) accession number: Q9HXT9
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: May 23, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

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