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Protein
Submitted name:

Probable two-component response regulator

Gene

wspR

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei194Cyclic diguanosine monophosphateCombined sources1
Binding sitei198Cyclic diguanosine monophosphateCombined sources1
Binding sitei262Cyclic diguanosine monophosphateCombined sources1
Binding sitei327Cyclic diguanosine monophosphateCombined sources1
Binding sitei331Cyclic diguanosine monophosphateCombined sources1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi212 – 215Cyclic diguanosine monophosphateCombined sources4
Nucleotide bindingi241 – 245Cyclic diguanosine monophosphateCombined sources5

GO - Molecular functioni

  • diguanylate cyclase activity Source: PseudoCAP
  • identical protein binding Source: IntAct
  • nucleotide binding Source: UniProtKB-KW

GO - Biological processi

Keywordsi

LigandNucleotide-bindingCombined sources

Names & Taxonomyi

Protein namesi
Submitted name:
Probable two-component response regulatorImported
Gene namesi
Name:wspRImported
Ordered Locus Names:PA3702Imported
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)Imported
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA3702.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei704-aspartylphosphatePROSITE-ProRule annotation1

Proteomic databases

PaxDbiQ9HXT9.
PRIDEiQ9HXT9.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
itself3EBI-15694918,EBI-15694918

GO - Molecular functioni

  • identical protein binding Source: IntAct

Protein-protein interaction databases

STRINGi208964.PA3702.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3BREX-ray2.40A/B1-347[»]
3I5BX-ray2.04A/B172-347[»]
3I5CX-ray1.94A/B172-347[»]
ProteinModelPortaliQ9HXT9.
SMRiQ9HXT9.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9HXT9.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 137Response regulatoryInterPro annotationAdd BLAST118
Domaini201 – 339GGDEFInterPro annotationAdd BLAST139

Phylogenomic databases

eggNOGiENOG4105BZU. Bacteria.
ENOG410XNMH. LUCA.
HOGENOMiHOG000167205.
InParanoidiQ9HXT9.
KOiK11444.
OMAiFIHKPAS.
PhylomeDBiQ9HXT9.

Family and domain databases

CDDicd01949. GGDEF. 1 hit.
cd00156. REC. 1 hit.
InterProiView protein in InterPro
IPR011006. CheY-like_superfamily.
IPR000160. GGDEF_dom.
IPR029787. Nucleotide_cyclase.
IPR001789. Sig_transdc_resp-reg_receiver.
PfamiView protein in Pfam
PF00990. GGDEF. 1 hit.
PF00072. Response_reg. 1 hit.
SMARTiView protein in SMART
SM00267. GGDEF. 1 hit.
SM00448. REC. 1 hit.
SUPFAMiSSF52172. SSF52172. 1 hit.
SSF55073. SSF55073. 1 hit.
TIGRFAMsiTIGR00254. GGDEF. 1 hit.
PROSITEiView protein in PROSITE
PS50887. GGDEF. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9HXT9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHNPHESKTD LGAPLDGAVM VLLVDDQAMI GEAVRRSLAS EAGIDFHFCS
60 70 80 90 100
DPQQAVAVAN QIKPTVILQD LVMPGVDGLT LLAAYRGNPA TRDIPIIVLS
110 120 130 140 150
TKEEPTVKSA AFAAGANDYL VKLPDAIELV ARIRYHSRSY IALQQRDEAY
160 170 180 190 200
RALRESQQQL LETNLVLQRL MNSDGLTGLS NRRHFDEYLE MEWRRSLREQ
210 220 230 240 250
SQLSLLMIDV DYFKSYNDTF GHVAGDEALR QVAGAIREGC SRSSDLAARY
260 270 280 290 300
GGEEFAMVLP GTSPGGARLL AEKVRRTVES LQISHDQPRP GSHLTVSIGV
310 320 330 340
STLVPGGGGQ TFRVLIEMAD QALYQAKNNG RNQVGLMEQP VPPAPAG
Length:347
Mass (Da):37,887
Last modified:March 1, 2001 - v1
Checksum:iAE706D630586649E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG07089.1.
PIRiE83183.
RefSeqiNP_252391.1. NC_002516.2.
WP_003103734.1. NC_002516.2.

Genome annotation databases

EnsemblBacteriaiAAG07089; AAG07089; PA3702.
GeneIDi878337.
KEGGipae:PA3702.
PATRICifig|208964.12.peg.3873.

Similar proteinsi

Entry informationi

Entry nameiQ9HXT9_PSEAE
AccessioniPrimary (citable) accession number: Q9HXT9
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: October 25, 2017
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported