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Protein
Submitted name:

Probable two-component response regulator

Gene

wspR

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei194Cyclic diguanosine monophosphateCombined sources1
Binding sitei198Cyclic diguanosine monophosphateCombined sources1
Binding sitei262Cyclic diguanosine monophosphateCombined sources1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi241 – 245Cyclic diguanosine monophosphateCombined sources5

GO - Molecular functioni

  • diguanylate cyclase activity Source: PseudoCAP
  • nucleotide binding Source: UniProtKB-KW

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

Nucleotide-bindingCombined sources

Names & Taxonomyi

Protein namesi
Submitted name:
Probable two-component response regulatorImported
Gene namesi
Name:wspRImported
Ordered Locus Names:PA3702Imported
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)Imported
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA3702.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ9HXT9.
PRIDEiQ9HXT9.

Interactioni

Protein-protein interaction databases

STRINGi208964.PA3702.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3I5BX-ray2.04A/B172-347[»]
3I5CX-ray1.94A/B172-347[»]
ProteinModelPortaliQ9HXT9.
SMRiQ9HXT9.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9HXT9.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 137Response regulatoryInterPro annotationAdd BLAST118
Domaini201 – 339GGDEFInterPro annotationAdd BLAST139

Phylogenomic databases

eggNOGiENOG4105BZU. Bacteria.
ENOG410XNMH. LUCA.
HOGENOMiHOG000167205.
InParanoidiQ9HXT9.
KOiK11444.
OMAiYLELEWR.
PhylomeDBiQ9HXT9.

Family and domain databases

CDDicd01949. GGDEF. 1 hit.
InterProiIPR011006. CheY-like_superfamily.
IPR000160. GGDEF_dom.
IPR029787. Nucleotide_cyclase.
IPR001789. Sig_transdc_resp-reg_receiver.
[Graphical view]
PfamiPF00990. GGDEF. 1 hit.
PF00072. Response_reg. 1 hit.
[Graphical view]
SMARTiSM00267. GGDEF. 1 hit.
SM00448. REC. 1 hit.
[Graphical view]
SUPFAMiSSF52172. SSF52172. 1 hit.
SSF55073. SSF55073. 1 hit.
TIGRFAMsiTIGR00254. GGDEF. 1 hit.
PROSITEiPS50887. GGDEF. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9HXT9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHNPHESKTD LGAPLDGAVM VLLVDDQAMI GEAVRRSLAS EAGIDFHFCS
60 70 80 90 100
DPQQAVAVAN QIKPTVILQD LVMPGVDGLT LLAAYRGNPA TRDIPIIVLS
110 120 130 140 150
TKEEPTVKSA AFAAGANDYL VKLPDAIELV ARIRYHSRSY IALQQRDEAY
160 170 180 190 200
RALRESQQQL LETNLVLQRL MNSDGLTGLS NRRHFDEYLE MEWRRSLREQ
210 220 230 240 250
SQLSLLMIDV DYFKSYNDTF GHVAGDEALR QVAGAIREGC SRSSDLAARY
260 270 280 290 300
GGEEFAMVLP GTSPGGARLL AEKVRRTVES LQISHDQPRP GSHLTVSIGV
310 320 330 340
STLVPGGGGQ TFRVLIEMAD QALYQAKNNG RNQVGLMEQP VPPAPAG
Length:347
Mass (Da):37,887
Last modified:March 1, 2001 - v1
Checksum:iAE706D630586649E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG07089.1.
PIRiE83183.
RefSeqiNP_252391.1. NC_002516.2.
WP_003103734.1. NZ_ASJY01000596.1.

Genome annotation databases

EnsemblBacteriaiAAG07089; AAG07089; PA3702.
GeneIDi878337.
KEGGipae:PA3702.
PATRICi19842031. VBIPseAer58763_3873.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG07089.1.
PIRiE83183.
RefSeqiNP_252391.1. NC_002516.2.
WP_003103734.1. NZ_ASJY01000596.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3I5BX-ray2.04A/B172-347[»]
3I5CX-ray1.94A/B172-347[»]
ProteinModelPortaliQ9HXT9.
SMRiQ9HXT9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi208964.PA3702.

Proteomic databases

PaxDbiQ9HXT9.
PRIDEiQ9HXT9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG07089; AAG07089; PA3702.
GeneIDi878337.
KEGGipae:PA3702.
PATRICi19842031. VBIPseAer58763_3873.

Organism-specific databases

PseudoCAPiPA3702.

Phylogenomic databases

eggNOGiENOG4105BZU. Bacteria.
ENOG410XNMH. LUCA.
HOGENOMiHOG000167205.
InParanoidiQ9HXT9.
KOiK11444.
OMAiYLELEWR.
PhylomeDBiQ9HXT9.

Miscellaneous databases

EvolutionaryTraceiQ9HXT9.

Family and domain databases

CDDicd01949. GGDEF. 1 hit.
InterProiIPR011006. CheY-like_superfamily.
IPR000160. GGDEF_dom.
IPR029787. Nucleotide_cyclase.
IPR001789. Sig_transdc_resp-reg_receiver.
[Graphical view]
PfamiPF00990. GGDEF. 1 hit.
PF00072. Response_reg. 1 hit.
[Graphical view]
SMARTiSM00267. GGDEF. 1 hit.
SM00448. REC. 1 hit.
[Graphical view]
SUPFAMiSSF52172. SSF52172. 1 hit.
SSF55073. SSF55073. 1 hit.
TIGRFAMsiTIGR00254. GGDEF. 1 hit.
PROSITEiPS50887. GGDEF. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9HXT9_PSEAE
AccessioniPrimary (citable) accession number: Q9HXT9
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: November 30, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.