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Protein

Protein translocase subunit SecF

Gene

secF

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Translocation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Protein translocase subunit SecF
Gene namesi
Name:secFUniRule annotation
Ordered Locus Names:PA3820
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA3820.

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei17 – 37HelicalUniRule annotationAdd BLAST21
Transmembranei134 – 154HelicalUniRule annotationAdd BLAST21
Transmembranei158 – 178HelicalUniRule annotationAdd BLAST21
Transmembranei185 – 205HelicalUniRule annotationAdd BLAST21
Transmembranei232 – 254HelicalUniRule annotationAdd BLAST23
Transmembranei268 – 288HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002878141 – 306Protein translocase subunit SecFAdd BLAST306

Proteomic databases

PaxDbiQ9HXI2.
PRIDEiQ9HXI2.

Interactioni

Subunit structurei

Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.UniRule annotation

Protein-protein interaction databases

STRINGi208964.PA3820.

Structurei

3D structure databases

ProteinModelPortaliQ9HXI2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SecD/SecF family. SecF subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4107RAB. Bacteria.
COG0341. LUCA.
HOGENOMiHOG000245914.
InParanoidiQ9HXI2.
KOiK03074.
OMAiMRWDNVA.
PhylomeDBiQ9HXI2.

Family and domain databases

HAMAPiMF_01464_B. SecF_B. 1 hit.
InterProiIPR022813. SecD/SecF_arch_bac.
IPR022645. SecD/SecF_bac.
IPR022646. SecD/SecF_CS.
IPR005665. SecF_bac.
[Graphical view]
PfamiPF07549. Sec_GG. 1 hit.
PF02355. SecD_SecF. 1 hit.
[Graphical view]
PRINTSiPR01755. SECFTRNLCASE.
TIGRFAMsiTIGR00916. 2A0604s01. 1 hit.
TIGR00966. 3a0501s07. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9HXI2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIKIGTINF MGIRNVAFAV TLILTVIALG SWFTKGINFG LDFTGGTLIE
60 70 80 90 100
LTYEQPADLG KVRGQLVGAG YEDAVVQSFG DARDVLVRMP SEDPELGKKV
110 120 130 140 150
ATALQQADAG NPANLKRVEY VGPQVGEELR DQGGLGMLLA LGGILLYVGF
160 170 180 190 200
RFQWKFALGA ILSLVHDAII VMGVLSFFQV TFDLTVLAAV LAVVGYSLND
210 220 230 240 250
TIVIFDRVRE NFRVLRKADL VENLNISTSQ TLLRTIATSV STLLAIAALL
260 270 280 290 300
FFGGDNLFGF SIALFVGVMA GTYSSIYIAN VVLIWLNLTS EDLIPPQAKD

TVDDRP
Length:306
Mass (Da):33,041
Last modified:March 1, 2001 - v1
Checksum:i7C078C8409DF9BA2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG07207.1.
PIRiE83169.
RefSeqiNP_252509.1. NC_002516.2.
WP_003100612.1. NZ_ASJY01000612.1.

Genome annotation databases

EnsemblBacteriaiAAG07207; AAG07207; PA3820.
GeneIDi879904.
KEGGipae:PA3820.
PATRICi19842283. VBIPseAer58763_3999.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG07207.1.
PIRiE83169.
RefSeqiNP_252509.1. NC_002516.2.
WP_003100612.1. NZ_ASJY01000612.1.

3D structure databases

ProteinModelPortaliQ9HXI2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi208964.PA3820.

Proteomic databases

PaxDbiQ9HXI2.
PRIDEiQ9HXI2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG07207; AAG07207; PA3820.
GeneIDi879904.
KEGGipae:PA3820.
PATRICi19842283. VBIPseAer58763_3999.

Organism-specific databases

PseudoCAPiPA3820.

Phylogenomic databases

eggNOGiENOG4107RAB. Bacteria.
COG0341. LUCA.
HOGENOMiHOG000245914.
InParanoidiQ9HXI2.
KOiK03074.
OMAiMRWDNVA.
PhylomeDBiQ9HXI2.

Family and domain databases

HAMAPiMF_01464_B. SecF_B. 1 hit.
InterProiIPR022813. SecD/SecF_arch_bac.
IPR022645. SecD/SecF_bac.
IPR022646. SecD/SecF_CS.
IPR005665. SecF_bac.
[Graphical view]
PfamiPF07549. Sec_GG. 1 hit.
PF02355. SecD_SecF. 1 hit.
[Graphical view]
PRINTSiPR01755. SECFTRNLCASE.
TIGRFAMsiTIGR00916. 2A0604s01. 1 hit.
TIGR00966. 3a0501s07. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSECF_PSEAE
AccessioniPrimary (citable) accession number: Q9HXI2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: March 1, 2001
Last modified: November 2, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.