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Q9HXB1

- IVY_PSEAE

UniProt

Q9HXB1 - IVY_PSEAE

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Protein

Inhibitor of vertebrate lysozyme

Gene

ivy

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Strong inhibitor of lysozyme C.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei86 – 861Important for lysozyme inhibitionBy similarity

GO - Biological processi

  1. negative regulation of catalytic activity Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Inhibitor of vertebrate lysozyme
Gene namesi
Name:ivy
Ordered Locus Names:PA3902
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000002438: Chromosome

Organism-specific databases

PseudoCAPiPA3902.

Subcellular locationi

GO - Cellular componenti

  1. periplasmic space Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2424Sequence AnalysisAdd
BLAST
Chaini25 – 153129Inhibitor of vertebrate lysozymePRO_0000016547Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi83 ↔ 88

Keywords - PTMi

Disulfide bond

Interactioni

Subunit structurei

Monomer.

Protein-protein interaction databases

DIPiDIP-60906N.
STRINGi208964.PA3902.

Structurei

Secondary structure

1
153
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi25 – 273
Helixi30 – 334
Helixi37 – 4610
Turni47 – 493
Helixi55 – 595
Beta strandi67 – 726
Beta strandi75 – 839
Turni88 – 903
Beta strandi91 – 988
Beta strandi104 – 1107
Helixi116 – 1194
Helixi122 – 1243
Beta strandi127 – 1326
Helixi136 – 14712

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1UUZX-ray1.80A/B25-153[»]
4PS6X-ray1.25A25-153[»]
ProteinModelPortaliQ9HXB1.
SMRiQ9HXB1. Positions 25-153.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9HXB1.

Family & Domainsi

Sequence similaritiesi

Belongs to the ivy family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG67654.
HOGENOMiHOG000280493.
InParanoidiQ9HXB1.
OMAiLAGEMCK.
OrthoDBiEOG68H883.
PhylomeDBiQ9HXB1.

Family and domain databases

Gene3Di3.40.1420.10. 1 hit.
InterProiIPR014453. Ihibitor_vertebrate_lysozyme.
[Graphical view]
PIRSFiPIRSF009103. Ivy. 1 hit.
SUPFAMiSSF89872. SSF89872. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9HXB1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNGVSRLLSL ALLGAALHWA PAQAEEQPRL FELLGQPGYK ATWHAMFKGE
60 70 80 90 100
SDVPKWVSDA SGPSSPSTSL SLEGQPYVLA NSCKPHDCGN NRLLVAFRGD
110 120 130 140 150
KSAAYGLQVS LPDEPAEVMQ TPSKYATYRW YGEPSRQVRE LLMKQLESDP

NWK
Length:153
Mass (Da):16,905
Last modified:March 1, 2001 - v1
Checksum:iAE64BE633EE77020
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE004091 Genomic DNA. Translation: AAG07289.1.
PIRiA83159.
RefSeqiNP_252591.1. NC_002516.2.

Genome annotation databases

EnsemblBacteriaiAAG07289; AAG07289; PA3902.
GeneIDi878927.
KEGGipae:PA3902.
PATRICi19842461. VBIPseAer58763_4087.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE004091 Genomic DNA. Translation: AAG07289.1 .
PIRi A83159.
RefSeqi NP_252591.1. NC_002516.2.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1UUZ X-ray 1.80 A/B 25-153 [» ]
4PS6 X-ray 1.25 A 25-153 [» ]
ProteinModelPortali Q9HXB1.
SMRi Q9HXB1. Positions 25-153.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-60906N.
STRINGi 208964.PA3902.

Protocols and materials databases

DNASUi 878927.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAG07289 ; AAG07289 ; PA3902 .
GeneIDi 878927.
KEGGi pae:PA3902.
PATRICi 19842461. VBIPseAer58763_4087.

Organism-specific databases

PseudoCAPi PA3902.

Phylogenomic databases

eggNOGi NOG67654.
HOGENOMi HOG000280493.
InParanoidi Q9HXB1.
OMAi LAGEMCK.
OrthoDBi EOG68H883.
PhylomeDBi Q9HXB1.

Miscellaneous databases

EvolutionaryTracei Q9HXB1.

Family and domain databases

Gene3Di 3.40.1420.10. 1 hit.
InterProi IPR014453. Ihibitor_vertebrate_lysozyme.
[Graphical view ]
PIRSFi PIRSF009103. Ivy. 1 hit.
SUPFAMi SSF89872. SSF89872. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.
  2. Abergel C.
    Unpublished observations (DEC-2001)
    Cited for: CHARACTERIZATION.

Entry informationi

Entry nameiIVY_PSEAE
AccessioniPrimary (citable) accession number: Q9HXB1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2001
Last sequence update: March 1, 2001
Last modified: October 29, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3