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Protein

Inhibitor of vertebrate lysozyme

Gene

ivy

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Strong inhibitor of lysozyme C.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei86Important for lysozyme inhibitionBy similarity1

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Inhibitor of vertebrate lysozyme
Gene namesi
Name:ivy
Ordered Locus Names:PA3902
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA3902.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_000001654725 – 153Inhibitor of vertebrate lysozymeAdd BLAST129

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi83 ↔ 88

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ9HXB1.

Interactioni

Subunit structurei

Monomer.

Protein-protein interaction databases

DIPiDIP-60906N.
STRINGi208964.PA3902.

Structurei

Secondary structure

1153
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi25 – 27Combined sources3
Helixi30 – 33Combined sources4
Helixi37 – 46Combined sources10
Turni47 – 49Combined sources3
Helixi55 – 59Combined sources5
Beta strandi67 – 72Combined sources6
Beta strandi75 – 83Combined sources9
Turni88 – 90Combined sources3
Beta strandi91 – 98Combined sources8
Beta strandi104 – 110Combined sources7
Helixi116 – 119Combined sources4
Helixi122 – 124Combined sources3
Beta strandi127 – 132Combined sources6
Helixi136 – 147Combined sources12

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1UUZX-ray1.80A/B25-153[»]
4PS6X-ray1.25A25-153[»]
ProteinModelPortaliQ9HXB1.
SMRiQ9HXB1.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9HXB1.

Family & Domainsi

Sequence similaritiesi

Belongs to the ivy family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4108ZGU. Bacteria.
ENOG4111SZM. LUCA.
HOGENOMiHOG000280493.
InParanoidiQ9HXB1.
OMAiHDCANNF.
PhylomeDBiQ9HXB1.

Family and domain databases

Gene3Di3.40.1420.10. 1 hit.
InterProiIPR014453. Ihibitor_vertebrate_lysozyme.
[Graphical view]
PIRSFiPIRSF009103. Ivy. 1 hit.
SUPFAMiSSF89872. SSF89872. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9HXB1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNGVSRLLSL ALLGAALHWA PAQAEEQPRL FELLGQPGYK ATWHAMFKGE
60 70 80 90 100
SDVPKWVSDA SGPSSPSTSL SLEGQPYVLA NSCKPHDCGN NRLLVAFRGD
110 120 130 140 150
KSAAYGLQVS LPDEPAEVMQ TPSKYATYRW YGEPSRQVRE LLMKQLESDP

NWK
Length:153
Mass (Da):16,905
Last modified:March 1, 2001 - v1
Checksum:iAE64BE633EE77020
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG07289.1.
PIRiA83159.
RefSeqiNP_252591.1. NC_002516.2.
WP_003093002.1. NZ_ASJY01000617.1.

Genome annotation databases

EnsemblBacteriaiAAG07289; AAG07289; PA3902.
GeneIDi878927.
KEGGipae:PA3902.
PATRICi19842461. VBIPseAer58763_4087.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG07289.1.
PIRiA83159.
RefSeqiNP_252591.1. NC_002516.2.
WP_003093002.1. NZ_ASJY01000617.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1UUZX-ray1.80A/B25-153[»]
4PS6X-ray1.25A25-153[»]
ProteinModelPortaliQ9HXB1.
SMRiQ9HXB1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-60906N.
STRINGi208964.PA3902.

Proteomic databases

PaxDbiQ9HXB1.

Protocols and materials databases

DNASUi878927.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG07289; AAG07289; PA3902.
GeneIDi878927.
KEGGipae:PA3902.
PATRICi19842461. VBIPseAer58763_4087.

Organism-specific databases

PseudoCAPiPA3902.

Phylogenomic databases

eggNOGiENOG4108ZGU. Bacteria.
ENOG4111SZM. LUCA.
HOGENOMiHOG000280493.
InParanoidiQ9HXB1.
OMAiHDCANNF.
PhylomeDBiQ9HXB1.

Miscellaneous databases

EvolutionaryTraceiQ9HXB1.

Family and domain databases

Gene3Di3.40.1420.10. 1 hit.
InterProiIPR014453. Ihibitor_vertebrate_lysozyme.
[Graphical view]
PIRSFiPIRSF009103. Ivy. 1 hit.
SUPFAMiSSF89872. SSF89872. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiIVY_PSEAE
AccessioniPrimary (citable) accession number: Q9HXB1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2001
Last sequence update: March 1, 2001
Last modified: November 2, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.