Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Bacteriophytochrome

Gene

bphP

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Photoreceptor which exists in two forms that are reversibly interconvertible by light: the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region.By similarity

Catalytic activityi

ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei12 – 121Tetrapyrrole chromophore (covalent; via 1 link)By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Photoreceptor protein, Receptor, Transferase

Keywords - Biological processi

Sensory transduction

Keywords - Ligandi

ATP-binding, Chromophore, Nucleotide-binding

Enzyme and pathway databases

BRENDAi2.7.13.3. 5087.

Names & Taxonomyi

Protein namesi
Recommended name:
Bacteriophytochrome (EC:2.7.13.3)
Alternative name(s):
Phytochrome-like protein
Gene namesi
Name:bphP
Ordered Locus Names:PA4117
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA4117.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 728728BacteriophytochromePRO_0000172000Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei513 – 5131Phosphohistidine; by autocatalysisPROSITE-ProRule annotation

Post-translational modificationi

Contains one covalently linked tetrapyrrole chromophore.By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ9HWR3.

Interactioni

Protein-protein interaction databases

DIPiDIP-46175N.
STRINGi208964.PA4117.

Structurei

Secondary structure

1
728
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Turni9 – 113Combined sources
Helixi12 – 143Combined sources
Beta strandi21 – 233Combined sources
Beta strandi27 – 326Combined sources
Beta strandi36 – 427Combined sources
Helixi45 – 495Combined sources
Helixi61 – 7616Combined sources
Beta strandi85 – 884Combined sources
Beta strandi90 – 934Combined sources
Beta strandi95 – 1028Combined sources
Beta strandi105 – 1128Combined sources
Helixi121 – 13616Combined sources
Helixi140 – 15516Combined sources
Beta strandi158 – 1658Combined sources
Turni167 – 1693Combined sources
Beta strandi171 – 1788Combined sources
Helixi192 – 1943Combined sources
Helixi197 – 2059Combined sources
Beta strandi207 – 2126Combined sources
Beta strandi219 – 2257Combined sources
Turni227 – 2293Combined sources
Beta strandi230 – 2323Combined sources
Helixi235 – 2373Combined sources
Beta strandi239 – 2413Combined sources
Helixi245 – 25410Combined sources
Beta strandi258 – 2658Combined sources
Beta strandi267 – 28014Combined sources
Helixi286 – 33247Combined sources
Helixi335 – 3406Combined sources
Turni342 – 3443Combined sources
Helixi346 – 3494Combined sources
Beta strandi353 – 3597Combined sources
Beta strandi362 – 3687Combined sources
Helixi371 – 38212Combined sources
Beta strandi388 – 3936Combined sources
Beta strandi410 – 4178Combined sources
Turni418 – 4214Combined sources
Beta strandi422 – 4287Combined sources
Beta strandi434 – 4407Combined sources
Helixi452 – 4543Combined sources
Helixi456 – 46712Combined sources
Helixi476 – 49318Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3C2WX-ray2.90A/B/C/D/E/F/G/H1-497[»]
3G6OX-ray2.85A/B1-497[»]
3IBRX-ray2.97A/B1-497[»]
3NHQX-ray2.55A/B/C/D/E/F/G/H1-497[»]
3NOPX-ray2.80C1-497[»]
3NOTX-ray2.70C1-497[»]
3NOUX-ray3.00C1-497[»]
ProteinModelPortaliQ9HWR3.
SMRiQ9HWR3. Positions 5-496, 500-705.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9HWR3.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini139 – 303165GAFAdd
BLAST
Domaini510 – 721212Histidine kinasePROSITE-ProRule annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni17 – 495479Chromophore binding domainAdd
BLAST

Sequence similaritiesi

In the N-terminal section; belongs to the phytochrome family.Curated
Contains 1 GAF domain.Curated
Contains 1 histidine kinase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105BZU. Bacteria.
ENOG410XNMH. LUCA.
HOGENOMiHOG000030537.
InParanoidiQ9HWR3.
OMAiANCADEP.
PhylomeDBiQ9HWR3.

Family and domain databases

Gene3Di1.10.287.130. 1 hit.
3.30.450.40. 1 hit.
3.30.565.10. 1 hit.
InterProiIPR003018. GAF.
IPR029016. GAF_dom-like.
IPR003594. HATPase_C.
IPR005467. His_kinase_dom.
IPR003661. HisK_dim/P.
IPR000014. PAS.
IPR013654. PAS_2.
IPR016132. Phyto_chromo_attachment.
IPR001294. Phytochrome.
IPR013515. Phytochrome_cen-reg.
[Graphical view]
PfamiPF01590. GAF. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF08446. PAS_2. 1 hit.
PF00360. PHY. 1 hit.
[Graphical view]
PRINTSiPR01033. PHYTOCHROME.
SMARTiSM00065. GAF. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 1 hit.
SSF55781. SSF55781. 2 hits.
SSF55785. SSF55785. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50046. PHYTOCHROME_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9HWR3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSITPVTLA NCEDEPIHVP GAIQPHGALV TLRADGMVLA ASENIQALLG
60 70 80 90 100
FVASPGSYLT QEQVGPEVLR MLEEGLTGNG PWSNSVETRI GEHLFDVIGH
110 120 130 140 150
SYKEVFYLEF EIRTADTLSI TSFTLNAQRI IAQVQLHNDT ASLLSNVTDE
160 170 180 190 200
LRRMTGYDRV MAYRFRHDDS GEVVAESRRE DLESYLGQRY PASDIPAQAR
210 220 230 240 250
RLYIQNPIRL IADVAYTPMR VFPALNPETN ESFDLSYSVL RSVSPIHCEY
260 270 280 290 300
LTNMGVRASM SISIVVGGKL WGLFSCHHMS PKLIPYPVRM SFQIFSQVCS
310 320 330 340 350
AIVERLEQGR IAELLRVSTE RRLALARRAR DADDLFGALA HPDDGIAALI
360 370 380 390 400
PCDGALVMLG GRTLSIRGDF ERQAGNVLQR LQRDPERDIY HTDNWPQPSE
410 420 430 440 450
DSPDGGDCCG VLAIRFHRQE SGWIFWFRHE EVHRIRWGGK PEKLLTIGPS
460 470 480 490 500
GPRLTPRGSF EAWEEVVRGH STPWSETDLA IAEKLRLDLM ELCLNHAAEV
510 520 530 540 550
DRMRQRLIAV LGHDLRNPLQ SISMAAALLS SSDTRTTELR QHISASSSRM
560 570 580 590 600
ERLVSQILDM SRLQSGIGLT VNPVDTDVSQ LVRQIVCETD VAYPGLVIEI
610 620 630 640 650
AIDPQVRAVV DPDRYAQVAA NLLSNARHHG LPGRPVLVTL TRQGDEVCLS
660 670 680 690 700
VLNETSGLSE AQLANLFEPF KRESADNQRN RNGLGIGLYI SQAIAQAHQG
710 720
RIDVDCRDDV ITFCLRLPVR QAETGSSS
Length:728
Mass (Da):80,931
Last modified:January 11, 2001 - v1
Checksum:iEEE9259392E5C4B0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG07504.1.
PIRiB83131.
RefSeqiNP_252806.1. NC_002516.2.
WP_003101278.1. NZ_ASJY01000659.1.

Genome annotation databases

EnsemblBacteriaiAAG07504; AAG07504; PA4117.
GeneIDi880365.
KEGGipae:PA4117.
PATRICi19842916. VBIPseAer58763_4314.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG07504.1.
PIRiB83131.
RefSeqiNP_252806.1. NC_002516.2.
WP_003101278.1. NZ_ASJY01000659.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3C2WX-ray2.90A/B/C/D/E/F/G/H1-497[»]
3G6OX-ray2.85A/B1-497[»]
3IBRX-ray2.97A/B1-497[»]
3NHQX-ray2.55A/B/C/D/E/F/G/H1-497[»]
3NOPX-ray2.80C1-497[»]
3NOTX-ray2.70C1-497[»]
3NOUX-ray3.00C1-497[»]
ProteinModelPortaliQ9HWR3.
SMRiQ9HWR3. Positions 5-496, 500-705.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-46175N.
STRINGi208964.PA4117.

Proteomic databases

PaxDbiQ9HWR3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG07504; AAG07504; PA4117.
GeneIDi880365.
KEGGipae:PA4117.
PATRICi19842916. VBIPseAer58763_4314.

Organism-specific databases

PseudoCAPiPA4117.

Phylogenomic databases

eggNOGiENOG4105BZU. Bacteria.
ENOG410XNMH. LUCA.
HOGENOMiHOG000030537.
InParanoidiQ9HWR3.
OMAiANCADEP.
PhylomeDBiQ9HWR3.

Enzyme and pathway databases

BRENDAi2.7.13.3. 5087.

Miscellaneous databases

EvolutionaryTraceiQ9HWR3.

Family and domain databases

Gene3Di1.10.287.130. 1 hit.
3.30.450.40. 1 hit.
3.30.565.10. 1 hit.
InterProiIPR003018. GAF.
IPR029016. GAF_dom-like.
IPR003594. HATPase_C.
IPR005467. His_kinase_dom.
IPR003661. HisK_dim/P.
IPR000014. PAS.
IPR013654. PAS_2.
IPR016132. Phyto_chromo_attachment.
IPR001294. Phytochrome.
IPR013515. Phytochrome_cen-reg.
[Graphical view]
PfamiPF01590. GAF. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF08446. PAS_2. 1 hit.
PF00360. PHY. 1 hit.
[Graphical view]
PRINTSiPR01033. PHYTOCHROME.
SMARTiSM00065. GAF. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 1 hit.
SSF55781. SSF55781. 2 hits.
SSF55785. SSF55785. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50046. PHYTOCHROME_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiBPHY_PSEAE
AccessioniPrimary (citable) accession number: Q9HWR3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: January 11, 2001
Last modified: September 7, 2016
This is version 121 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.