Q9HWG4 (Q9HWG4_PSEAE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Pyochelin synthetase EMBL AAG07613.1

Gene names

Name:	pchF EMBL AAG07613.1
Ordered Locus Names:	PA4225

Organism

Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)

Taxonomic identifier

208964 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	1809 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Ligand	Phosphopantetheine RuleBase RU000721
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	acyl carrier activity Inferred from electronic annotation. Source: InterPro cofactor binding Inferred from electronic annotation. Source: InterPro hydrolase activity, acting on ester bonds Inferred from electronic annotation. Source: InterPro ligase activity Inferred from electronic annotation. Source: InterPro phosphopantetheine binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9HWG4 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 39978C86A1BB5F0B	FASTA	1,809	197,084
	10 20 30 40 50 60 MSLGELLETC RSRRIELWSE AGRLRYRAPQ GALDAGLAER LRAEREALLE HLEGGPGWRA 70 80 90 100 110 120 EPDMAHQRFP LTPVQAAYVL GRQAAFDYGG NACQLYAEYD WPADTDPARL EAAWNAMVER 130 140 150 160 170 180 HPMLRAVIED NAWQRVLPEV PWQRLTVHAC AGLDEAAFQA HLERVRERLD HACAALDQWP 190 200 210 220 230 240 VLRPELSIGR DACVLHCSVD FTLVDYASLQ LLLGEWRRRY LDPQWTAEPL EATFRDYVGV 250 260 270 280 290 300 EQRRRQSPAW QRDRDWWLAR LDALPGRPDL PLRVQPDTRS TRFRHFHARL DEAAWQALGA 310 320 330 340 350 360 RAGEHGLSAA GVALAAFAET IGRWSQAPAF CLNLTVLNRP PLHPQLAQVL GDFTALSLLA 370 380 390 400 410 420 VDSRHGDSFV ERARRIGEQM FDDLDHPTFS GVDLLRELAR RRGRGADLMP VVFTSGIGSV 430 440 450 460 470 480 QRLLGDGEAP RAPRYMISQT PQVWLDCQVT DQFGGLEIGW DVRLGLFPEG QAEAMFDDFV 490 500 510 520 530 540 GLLRRLAQSP RAWTDGDATE PVEAPPQALP GSARSIAAGF AERALLTPDA TAIHDAAGSY 550 560 570 580 590 600 SYRQVAQHAS ALRRVLEAHG AGRGRRVAVM LPKSAAQLVA VIGILQAGAA YVPVDIRQPP 610 620 630 640 650 660 LRRQAILASA EVVALVCLES DVPDVGCACV AIDRLAADSA WPPPPAAEVA ADDLAYVIYT 670 680 690 700 710 720 SGSTGTPKGV MLSHAAVSNT LLDINQRYGV DANDRVLGLA ELSFDLSVYD FFGATAAGAQ 730 740 750 760 770 780 VVLPDPARGS DPSHWAELLE RHAITLWNSV PAQGQMLIDY LESEPQRHLP GPRCVLWSGD 790 800 810 820 830 840 WIPVSLPTRW WRRWPDSALF SLGGATEAAI WSIEQPIRPQ HTELASIPYG RALRGQSVEV 850 860 870 880 890 900 LDARGRRCPP GVRGEIHIGG VGLALGYAGD PQRTAERFVR HPDGRRLYRT GDLGRYLADG 910 920 930 940 950 960 SIEFLGREDD QVKIRGHRIE LAELDAALCA HPQVNLAATV VLGETHERSL ASFVTLHAPV 970 980 990 1000 1010 1020 EAGEDPRTAL DAVRQRAAQA LRRDWGSEEG IAAAVAALDR ACLASLAAWL AGSGLFASAT 1030 1040 1050 1060 1070 1080 PLDLATLCQR LGIAEARQRL LRHWLRQLEE GGYLRAEGEG WLGCAERPAQ SPEDAWTAFA 1090 1100 1110 1120 1130 1140 GCAPAALWPA ELVAYLRDSA QSLGEQLAGR ISPAALMFPQ GSARIAEAMY SQGLHAQALH 1150 1160 1170 1180 1190 1200 EAMAEAIAAI VERQPQRRWR LLELGAGTAA ASRTVIARLA PLVQRGAEVD YLFTDVSSYF 1210 1220 1230 1240 1250 1260 LAAARERFAD QPWVRFGRFD MNGDLLDQGV APHSVDILLS SGALNNALDT PALLAGLREL 1270 1280 1290 1300 1310 1320 LSADAWLVIQ ELTREHNEIS VSQSLMMENP RDLRDERRQL FVHTGQWLEW LAAQGGDLAC 1330 1340 1350 1360 1370 1380 GVVPPGSALD LLGYDVLLAR CKTDRARLEP AELLAFVEAR VPRYMLPAQL RVLERLPVTG 1390 1400 1410 1420 1430 1440 NGKIDRKALT GFARQPQADL RHGVAQAPAD ELENALLALW REVLDNPSLG VEQDFFGAGG 1450 1460 1470 1480 1490 1500 DSLLIAQLIA RLRERLESAR RHPFDRLLRW ALSQPTPRGL AERLRSAPEE GRGPALAAAR 1510 1520 1530 1540 1550 1560 GVAPAPAGMS RAPLAEGAVA LDPLVRLVPG EGVPRVLVHE GLGTLLPYRP LLRALGEGRP 1570 1580 1590 1600 1610 1620 LLGLAVHDSD AYLAIPAEHL NACLGRRYAE ALHRAGLREV DLLGYCSGGL VALETAKSLV 1630 1640 1650 1660 1670 1680 QRGVRVRQLD IVSSYRIPYR VDDERLLLFS FAATLGLDTA ALGFPAPERL GQAVQAALAQ 1690 1700 1710 1720 1730 1740 TPERLVAEAL AGLPGLADLV ALRGRVLQAA SGSADAVSVE RDTLYRLFCH SVRASQAEAP 1750 1760 1770 1780 1790 1800 EPYVGALRLF VPDAGNPLVP RYAEALETQW RAAALGACGI HEVPGGHFDC LGEALAQSLS KPMPEEASR

References

[1]

"Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen." Stover C.K., Pham X.Q., Erwin A.L., Mizoguchi S.D., Warrener P., Hickey M.J., Brinkman F.S., Hufnagle W.O., Kowalik D.J., Lagrou M., Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y., Brody L.L., Coulter S.N., Folger K.R. , Kas A., Larbig K., Lim R., Smith K., Spencer D., Wong G.K., Wu Z., Paulsen I.T., Reizer J., Saier M.H., Hancock R.E., Lory S., Olson M.V. Nature 406:959-964(2000) [PubMed: 10984043] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE004091 Genomic DNA. Translation: AAG07613.1.
PIR	C83118.
RefSeq	NP_252915.1. NC_002516.2.
3D structure databases
HSSP	HSSP built from PDB template 1AMU based on UniProtKB P14687.
ProteinModelPortal	Q9HWG4.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	880083.
GenomeReviews	Gene locus PA4225 in contig AE004091_GR.
KEGG	pae:PA4225.
NMPDR	fig|208964.1.peg.4225.
PATRIC	19843140. VBIPseAer58763_4426.
Organism-specific databases
PseudoCAP	PA4225.
Phylogenomic databases
HOGENOM	HBG676528.
OMA	NSVPAQM.
ProtClustDB	CLSK868536.
Enzyme and pathway databases
BioCyc	PAER208964:PA4225-MONOMER.
Family and domain databases
InterPro	IPR010071. AA_adenyl_domain. IPR009081. Acyl_carrier_prot-like. IPR020459. AMP-binding. IPR020845. AMP-binding_CS. IPR000873. AMP-dep_Synth/Lig. IPR001242. Condensatn. IPR013217. Methyltransf_12. IPR013624. NRPS. IPR006163. Phsphopanteth-bd. IPR006162. PPantetheine_attach_site. IPR001031. Thioesterase. [Graphical view]
Gene3D	G3DSA:1.10.1200.10. ACP_like. 1 hit.
KO	K12240.
Pfam	PF00501. AMP-binding. 1 hit. PF00668. Condensation. 1 hit. PF08242. Methyltransf_12. 1 hit. PF08415. NRPS. 1 hit. PF00550. PP-binding. 1 hit. PF00975. Thioesterase. 1 hit. [Graphical view]
PRINTS	PR00154. AMPBINDING.
SUPFAM	SSF47336. ACP_like. 1 hit.
TIGRFAMs	TIGR01733. AA-adenyl-dom. 1 hit.
PROSITE	PS50075. ACP_DOMAIN. 1 hit. PS00455. AMP_BINDING. 1 hit. PS00012. PHOSPHOPANTETHEINE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9HWG4_PSEAE

Accession

Primary (citable) accession number: Q9HWG4

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2001
Last sequence update:	March 1, 2001
Last modified:	December 14, 2011
This is version 73 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)