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Protein

50S ribosomal protein L5

Gene

rplE

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding, tRNA-binding

Enzyme and pathway databases

BioCyciPAER208964:G1FZ6-4324-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L5UniRule annotation
Gene namesi
Name:rplEUniRule annotation
Ordered Locus Names:PA4251
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA4251

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001249701 – 17950S ribosomal protein L5Add BLAST179

Proteomic databases

PaxDbiQ9HWE7
PRIDEiQ9HWE7

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.UniRule annotation

Protein-protein interaction databases

STRINGi208964.PA4251

Structurei

3D structure databases

ProteinModelPortaliQ9HWE7
SMRiQ9HWE7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the universal ribosomal protein uL5 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CW6 Bacteria
COG0094 LUCA
HOGENOMiHOG000231311
InParanoidiQ9HWE7
KOiK02931
OMAiEQVMFHE
PhylomeDBiQ9HWE7

Family and domain databases

Gene3Di3.30.1440.10, 1 hit
HAMAPiMF_01333_B Ribosomal_L5_B, 1 hit
InterProiView protein in InterPro
IPR002132 Ribosomal_L5
IPR020930 Ribosomal_L5_bac-type
IPR031309 Ribosomal_L5_C
IPR020929 Ribosomal_L5_CS
IPR022803 Ribosomal_L5_dom_sf
IPR031310 Ribosomal_L5_N
PANTHERiPTHR11994 PTHR11994, 1 hit
PfamiView protein in Pfam
PF00281 Ribosomal_L5, 1 hit
PF00673 Ribosomal_L5_C, 1 hit
PIRSFiPIRSF002161 Ribosomal_L5, 1 hit
SUPFAMiSSF55282 SSF55282, 1 hit
PROSITEiView protein in PROSITE
PS00358 RIBOSOMAL_L5, 1 hit

Sequencei

Sequence statusi: Complete.

Q9HWE7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARLKEIYRK EIAPKLKEEL QLANVMEVPR VTKITLNMGL GEAVGDKKII
60 70 80 90 100
ENAVADLEKI TGQKPVVTYA RKSIAGFKIR EGWPIGVKVT LRSDRMYEFL
110 120 130 140 150
DRLLSISLPR VRDFRGLNAK SFDGRGNYSM GVKEQIIFPE IDYDKIDALR
160 170
GLDITLTTTA RTDDEGRALL RAFKFPFRN
Length:179
Mass (Da):20,392
Last modified:March 1, 2001 - v1
Checksum:iA30DF235F4ABD153
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA Translation: AAG07639.1
PIRiA83115
RefSeqiNP_252941.1, NC_002516.2
WP_003093703.1, NC_002516.2

Genome annotation databases

EnsemblBacteriaiAAG07639; AAG07639; PA4251
GeneIDi881779
KEGGipae:PA4251
PATRICifig|208964.12.peg.4452

Similar proteinsi

Entry informationi

Entry nameiRL5_PSEAE
AccessioniPrimary (citable) accession number: Q9HWE7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: March 1, 2001
Last modified: February 28, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

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