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Protein

Protein translocase subunit SecE

Gene

secE

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Translocation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Protein translocase subunit SecEUniRule annotation
Gene namesi
Name:secEUniRule annotation
Ordered Locus Names:PA4276
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA4276.

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei14 – 3421HelicalUniRule annotationAdd
BLAST
Transmembranei38 – 5821HelicalUniRule annotationAdd
BLAST
Transmembranei93 – 11321HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 122122Protein translocase subunit SecEPRO_0000287811Add
BLAST

Proteomic databases

PaxDbiQ9HWC3.

Interactioni

Subunit structurei

Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.UniRule annotation

Protein-protein interaction databases

STRINGi208964.PA4276.

Structurei

3D structure databases

ProteinModelPortaliQ9HWC3.
SMRiQ9HWC3. Positions 12-122.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SecE/SEC61-gamma family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105PM1. Bacteria.
COG0690. LUCA.
HOGENOMiHOG000219148.
InParanoidiQ9HWC3.
KOiK03073.
OMAiEAKDSRF.
OrthoDBiEOG6DRPR4.
PhylomeDBiQ9HWC3.

Family and domain databases

HAMAPiMF_00422. SecE.
InterProiIPR022943. SecE.
IPR005807. SecE_bac.
IPR001901. Translocase_SecE/Sec61-g.
[Graphical view]
PfamiPF00584. SecE. 1 hit.
[Graphical view]
PRINTSiPR01650. SECETRNLCASE.
TIGRFAMsiTIGR00964. secE_bact. 1 hit.
PROSITEiPS01067. SECE_SEC61G. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9HWC3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNAKAEAKES RFDLLKWLLV AVLVVVAVVG NQYFSAQPIL YRVLGILVLA
60 70 80 90 100
VIAAFLALQT AKGQAFFSLA KEARVEIRKV VWPSRQETTQ TTLIVVAVVL
110 120
VMALLLWGLD SLLGWLVSMI VG
Length:122
Mass (Da):13,381
Last modified:March 1, 2001 - v1
Checksum:iF6696871DFA5D4BC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG07664.1.
PIRiE83111.
RefSeqiNP_252966.1. NC_002516.2.
WP_003108030.1. NZ_ASJY01000705.1.

Genome annotation databases

EnsemblBacteriaiAAG07664; AAG07664; PA4276.
GeneIDi881694.
KEGGipae:PA4276.
PATRICi19843243. VBIPseAer58763_4477.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG07664.1.
PIRiE83111.
RefSeqiNP_252966.1. NC_002516.2.
WP_003108030.1. NZ_ASJY01000705.1.

3D structure databases

ProteinModelPortaliQ9HWC3.
SMRiQ9HWC3. Positions 12-122.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi208964.PA4276.

Proteomic databases

PaxDbiQ9HWC3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG07664; AAG07664; PA4276.
GeneIDi881694.
KEGGipae:PA4276.
PATRICi19843243. VBIPseAer58763_4477.

Organism-specific databases

PseudoCAPiPA4276.

Phylogenomic databases

eggNOGiENOG4105PM1. Bacteria.
COG0690. LUCA.
HOGENOMiHOG000219148.
InParanoidiQ9HWC3.
KOiK03073.
OMAiEAKDSRF.
OrthoDBiEOG6DRPR4.
PhylomeDBiQ9HWC3.

Family and domain databases

HAMAPiMF_00422. SecE.
InterProiIPR022943. SecE.
IPR005807. SecE_bac.
IPR001901. Translocase_SecE/Sec61-g.
[Graphical view]
PfamiPF00584. SecE. 1 hit.
[Graphical view]
PRINTSiPR01650. SECETRNLCASE.
TIGRFAMsiTIGR00964. secE_bact. 1 hit.
PROSITEiPS01067. SECE_SEC61G. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.

Entry informationi

Entry nameiSECE_PSEAE
AccessioniPrimary (citable) accession number: Q9HWC3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: March 1, 2001
Last modified: July 6, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.