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Protein

TPR repeat-containing protein PA4299

Gene

PA4299

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
TPR repeat-containing protein PA4299
Gene namesi
Ordered Locus Names:PA4299
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA4299.

Subcellular locationi

  • Cell membrane PROSITE-ProRule annotation; Lipid-anchor PROSITE-ProRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 16PROSITE-ProRule annotationAdd BLAST16
ChainiPRO_000028777917 – 245TPR repeat-containing protein PA4299Add BLAST229

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi17N-palmitoyl cysteinePROSITE-ProRule annotation1
Lipidationi17S-diacylglycerol cysteinePROSITE-ProRule annotation1

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PaxDbiQ9HWA1.

Interactioni

Protein-protein interaction databases

STRINGi208964.PA4299.

Structurei

3D structure databases

ProteinModelPortaliQ9HWA1.
SMRiQ9HWA1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati100 – 133TPR 1Add BLAST34
Repeati135 – 167TPR 2Add BLAST33
Repeati169 – 200TPR 3Add BLAST32

Sequence similaritiesi

Contains 3 TPR repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Signal, TPR repeat

Phylogenomic databases

eggNOGiENOG4105VK0. Bacteria.
COG5010. LUCA.
HOGENOMiHOG000247622.
OMAiRFEFITA.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
InterProiIPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR019734. TPR_repeat.
IPR016931. UCP029658_TPR.
[Graphical view]
PIRSFiPIRSF029658. UCP029658_TPR. 1 hit.
SUPFAMiSSF48452. SSF48452. 1 hit.
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
PS50005. TPR. 1 hit.
PS50293. TPR_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9HWA1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKALIGIGLC AALLGGCAAL PGRDGPRECS QQLGQEQELQ MNMVRDMIRE
60 70 80 90 100
GRLHAALANL ESMPPGLLDV REERALILRR IGDPRARAEY QALLETCKAP
110 120 130 140 150
EAHHGLGLLA LRNGDSARAV LELREAARLR PTESRFRNDL GVALLKRGDR
160 170 180 190 200
VGARFEFITA LELQQGGKLP ATNLLGLLYL QGDREDAQRL IERLQLDARD
210 220 230 240
IRAAEARARS WGAVPTPGAA PASDDPLAEL PAEANMHTAM ANEAP
Length:245
Mass (Da):26,583
Last modified:March 1, 2001 - v1
Checksum:i89C5897500FC25BE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG07687.1.
PIRiB83108.
RefSeqiNP_252989.1. NC_002516.2.
WP_003114982.1. NC_002516.2.

Genome annotation databases

EnsemblBacteriaiAAG07687; AAG07687; PA4299.
GeneIDi881552.
KEGGipae:PA4299.
PATRICi19843309. VBIPseAer58763_4501.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG07687.1.
PIRiB83108.
RefSeqiNP_252989.1. NC_002516.2.
WP_003114982.1. NC_002516.2.

3D structure databases

ProteinModelPortaliQ9HWA1.
SMRiQ9HWA1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi208964.PA4299.

Proteomic databases

PaxDbiQ9HWA1.

Protocols and materials databases

DNASUi881552.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG07687; AAG07687; PA4299.
GeneIDi881552.
KEGGipae:PA4299.
PATRICi19843309. VBIPseAer58763_4501.

Organism-specific databases

PseudoCAPiPA4299.

Phylogenomic databases

eggNOGiENOG4105VK0. Bacteria.
COG5010. LUCA.
HOGENOMiHOG000247622.
OMAiRFEFITA.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
InterProiIPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR019734. TPR_repeat.
IPR016931. UCP029658_TPR.
[Graphical view]
PIRSFiPIRSF029658. UCP029658_TPR. 1 hit.
SUPFAMiSSF48452. SSF48452. 1 hit.
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
PS50005. TPR. 1 hit.
PS50293. TPR_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiY4299_PSEAE
AccessioniPrimary (citable) accession number: Q9HWA1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: March 1, 2001
Last modified: November 2, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.