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Q9HW26 (PNCB2_PSEAE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 96. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase 2

Short name=NAPRTase 2
EC=6.3.4.21
Gene names
Name:pncB2
Ordered Locus Names:PA4376
OrganismPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) [Reference proteome] [HAMAP]
Taxonomic identifier208964 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length398 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 398398Nicotinate phosphoribosyltransferase 2 HAMAP-Rule MF_00570
PRO_0000205838

Secondary structure

............................................................ 398
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q9HW26 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: 526899B1B705C37F

FASTA39845,691
        10         20         30         40         50         60 
MAESAFSERI VQNLLDTDFY KLTMMQAVLH NYPNAEVEWE FRCRNQEDLR LYLPAIREQL 

        70         80         90        100        110        120 
EYLAGLAISD EQLAFLERIP FLAPDFIRFL GLFRFNPRYV QTGIENDEFF LRLKGPWLHV 

       130        140        150        160        170        180 
ILFEVPLLAM ISEVRNRARY PAATVEQARE RLQEKFDWLR REASAEELAG FKMADFGTRR 

       190        200        210        220        230        240 
RFSYRVHEAV VSGLKEDFPG CFVGTSNVHL ARKLDLKPLG TMAHEWLMAH QQLGPRLIDS 

       250        260        270        280        290        300 
QSAALDCWVR EYRGLLGIAL TDCITTDAFL RDFDLYFAKL FDGLRHDSGD PLLWAEKTIA 

       310        320        330        340        350        360 
HYLKLGIDPL TKTLVFSDGL DLPRALKIYR ALQGRINVSF GIGTHFTCDL PGVEPMNIVV 

       370        380        390 
KMSACNGHPV AKISDTPGKA QCRDPDFIHY LKHVFQVA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE004091 Genomic DNA. Translation: AAG07764.1.
PIRF83099.
RefSeqNP_253066.1. NC_002516.2.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1YIRX-ray2.10A/B/C/D2-398[»]
ProteinModelPortalQ9HW26.
SMRQ9HW26. Positions 1-397.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING208964.PA4376.

Proteomic databases

PRIDEQ9HW26.

Protocols and materials databases

DNASU881378.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID881378.
KEGGpae:PA4376.
PATRIC19843473. VBIPseAer58763_4583.

Organism-specific databases

PseudoCAPPA4376.

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284928.
KOK00763.
OMATPGKGMC.
OrthoDBEOG6X10XB.
ProtClustDBPRK05321.

Enzyme and pathway databases

UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Other

EvolutionaryTraceQ9HW26.

Entry information

Entry namePNCB2_PSEAE
AccessionPrimary (citable) accession number: Q9HW26
Entry history
Integrated into UniProtKB/Swiss-Prot: July 11, 2002
Last sequence update: March 1, 2001
Last modified: April 16, 2014
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

PATHWAY comments

Index of metabolic and biosynthesis pathways