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Reviewed, UniProtKB/Swiss-Prot Q9HW26 (PNCB2_PSEAE)

Last modified November 3, 2009. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Nicotinate phosphoribosyltransferase 2
      Short name=NAPRTase 2
    EC=2.4.2.11
Gene names
Name: pncB2
Ordered Locus Names: PA4376
OrganismPseudomonas aeruginosa [Complete proteome] [HAMAP]
Taxonomic identifier287 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length398 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

General annotation (Comments)

Catalytic activity

Nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP MF_00570

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the NAPRTase family.

Ontologies

Keywords
   Biological processPyridine nucleotide biosynthesis
   Cellular componentCytoplasm
   Molecular functionGlycosyltransferase
Transferase
   Technical term3D-structure
Complete proteome
Gene Ontology (GO)
   Biological processNAD biosynthetic process

Inferred from electronic annotation. Source: HAMAP

nicotinate nucleotide biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionnicotinate phosphoribosyltransferase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 398398Nicotinate phosphoribosyltransferase 2 HAMAP MF_00570
PRO_0000205838

Secondary structure

............................................................ 398
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q9HW26-1 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: 526899B1B705C37F

FASTA39845,691
        10         20         30         40         50         60 
MAESAFSERI VQNLLDTDFY KLTMMQAVLH NYPNAEVEWE FRCRNQEDLR LYLPAIREQL 

        70         80         90        100        110        120 
EYLAGLAISD EQLAFLERIP FLAPDFIRFL GLFRFNPRYV QTGIENDEFF LRLKGPWLHV 

       130        140        150        160        170        180 
ILFEVPLLAM ISEVRNRARY PAATVEQARE RLQEKFDWLR REASAEELAG FKMADFGTRR 

       190        200        210        220        230        240 
RFSYRVHEAV VSGLKEDFPG CFVGTSNVHL ARKLDLKPLG TMAHEWLMAH QQLGPRLIDS 

       250        260        270        280        290        300 
QSAALDCWVR EYRGLLGIAL TDCITTDAFL RDFDLYFAKL FDGLRHDSGD PLLWAEKTIA 

       310        320        330        340        350        360 
HYLKLGIDPL TKTLVFSDGL DLPRALKIYR ALQGRINVSF GIGTHFTCDL PGVEPMNIVV 

       370        380        390 
KMSACNGHPV AKISDTPGKA QCRDPDFIHY LKHVFQVA 

« Hide

Cross-references

Sequence databases

AE004091 Genomic DNA. Translation: AAG07764.1.
PIRF83099.
RefSeqNP_253066.1.

3D structure databases

EntryMethodResolution (Å)ChainPositionsPDBsum
1YIRX-ray2.10A/B/C/D2-398[»]
ModBaseSearch...

Genome annotation databases

GeneID881378.
GenomeReviewsGene locus PA4376 in contig AE004091_GR.
KEGGpae:PA4376.

Organism-specific databases

PseudoCAPPA4376.
CMRSearch...

Phylogenomic databases

HOGENOMQ9HW26.
OMAIREQIEY.

Enzyme and pathway databases

BioCycPAER208964:PA4376-MON.
BRENDA2.4.2.11. 354.

Family and domain databases

HAMAPMF_00570.
[Tree]
InterProIPR006406. Nic_PRibTrfase.
IPR015977. Nic_PRibTrfase-like.
IPR007229. Nic_PRibTrfase-rel.
[Graphical view]
PANTHERPTHR11098:SF1. NAPRTase. 1 hit.
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB2_PSEAE
AccessionPrimary (citable) accession number: Q9HW26
Entry history
Integrated into UniProtKB/Swiss-Prot: July 11, 2002
Last sequence update: March 1, 2001
Last modified: November 3, 2009
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents