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Protein

Endolytic peptidoglycan transglycosylase RlpA

Gene

rlpA

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.UniRule annotation

Keywordsi

Molecular functionLyaseUniRule annotation
Biological processCell wall biogenesis/degradationUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Endolytic peptidoglycan transglycosylase RlpAUniRule annotation (EC:4.2.2.-UniRule annotation)
Gene namesi
Name:rlpAUniRule annotation
Ordered Locus Names:PA4485Imported
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)Imported
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA4485.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26UniRule annotationAdd BLAST26
ChainiPRO_500999266227 – 125Endolytic peptidoglycan transglycosylase RlpAUniRule annotationAdd BLAST99

Proteomic databases

PaxDbiQ9HVT6.

Interactioni

Protein-protein interaction databases

STRINGi208964.PA4485.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4AVRX-ray1.08A/B32-125[»]
ProteinModelPortaliQ9HVT6.
SMRiQ9HVT6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini33 – 121DPBB_1InterPro annotationAdd BLAST89

Sequence similaritiesi

Belongs to the RlpA family.UniRule annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiENOG4105K6T. Bacteria.
COG0797. LUCA.
HOGENOMiHOG000254768.
InParanoidiQ9HVT6.
KOiK03642.
OMAiYNPNAMT.
PhylomeDBiQ9HVT6.

Family and domain databases

Gene3Di2.40.40.10. 1 hit.
HAMAPiMF_02071. RlpA. 1 hit.
InterProiView protein in InterPro
IPR034718. RlpA.
IPR009009. RlpA-like_DPBB.
IPR012997. RplA.
PfamiView protein in Pfam
PF03330. DPBB_1. 1 hit.
SUPFAMiSSF50685. SSF50685. 1 hit.
TIGRFAMsiTIGR00413. rlpA. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9HVT6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPTPSAAARL ALAVLPLFLA GCSSLAGSGS ADTGEASYYG SRHAGLRTAS
60 70 80 90 100
GERYNPNAMT AAHRTLPFGA RVRVTNLDNR RSVVVRINDR GPFRRGRIID
110 120
VSRKAAEGLG MIRSGVAPVR IESLD
Length:125
Mass (Da):13,221
Last modified:March 1, 2001 - v1
Checksum:i30F35A7A064F5F2E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG07873.1.
PIRiB83085.
RefSeqiNP_253175.1. NC_002516.2.
WP_003112869.1. NZ_ASJY01000731.1.

Genome annotation databases

EnsemblBacteriaiAAG07873; AAG07873; PA4485.
GeneIDi881190.
KEGGipae:PA4485.
PATRICi19843697. VBIPseAer58763_4695.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG07873.1.
PIRiB83085.
RefSeqiNP_253175.1. NC_002516.2.
WP_003112869.1. NZ_ASJY01000731.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4AVRX-ray1.08A/B32-125[»]
ProteinModelPortaliQ9HVT6.
SMRiQ9HVT6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi208964.PA4485.

Proteomic databases

PaxDbiQ9HVT6.

Protocols and materials databases

DNASUi881190.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG07873; AAG07873; PA4485.
GeneIDi881190.
KEGGipae:PA4485.
PATRICi19843697. VBIPseAer58763_4695.

Organism-specific databases

PseudoCAPiPA4485.

Phylogenomic databases

eggNOGiENOG4105K6T. Bacteria.
COG0797. LUCA.
HOGENOMiHOG000254768.
InParanoidiQ9HVT6.
KOiK03642.
OMAiYNPNAMT.
PhylomeDBiQ9HVT6.

Family and domain databases

Gene3Di2.40.40.10. 1 hit.
HAMAPiMF_02071. RlpA. 1 hit.
InterProiView protein in InterPro
IPR034718. RlpA.
IPR009009. RlpA-like_DPBB.
IPR012997. RplA.
PfamiView protein in Pfam
PF03330. DPBB_1. 1 hit.
SUPFAMiSSF50685. SSF50685. 1 hit.
TIGRFAMsiTIGR00413. rlpA. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ9HVT6_PSEAE
AccessioniPrimary (citable) accession number: Q9HVT6
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: April 12, 2017
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.