Reviewed, UniProtKB/Swiss-Prot Q9HVF1 (MQO2_PSEAE)

Names and origin

Protein names

Recommended name:
    Probable malate:quinone oxidoreductase 2
    EC=1.1.99.16
Alternative name(s):
    Malate dehydrogenase [acceptor] 2
    MQO 2

Gene names

Name:	mqo2
Synonyms:	mqoB
Ordered Locus Names:	PA4640

Organism

Pseudomonas aeruginosa [Complete proteome] [HAMAP]

Taxonomic identifier

287 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	507 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(S)-malate + acceptor = oxaloacetate + reduced acceptor. HAMAP MF_00212
Cofactor	FAD By similarity.
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW tricarboxylic acid cycle Inferred from electronic annotation. Source: HAMAP
Molecular function	malate dehydrogenase (acceptor) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 507	507	Probable malate:quinone oxidoreductase 2 HAMAP MF_00212		PRO_0000128730

Sequences

	Sequence		Length	Mass (Da)
	Q9HVF1-1 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 0A7F91E4172CAA8D	FASTA	507	55,498
	10 20 30 40 50 60 MAQNDHETVD MLLVGAGIMS ATLAVLLKEL DPNLKMEVVE LQESGAIESS NPWNNAGTGH 70 80 90 100 110 120 AGLCELNYTP QSADGSIDIK KAVGINTMFE VSKQFWSHLV AKGTFGSPKT FINPVPHLSF 130 140 150 160 170 180 VRGSEGIAYL KKRFESLTKH HAFETMVYSE DKATLAEWMP LMMPGRPADE AIAATRVEGG 190 200 210 220 230 240 TDVNFGALTN QLLQHLAQQP GAQIRYNQKV THLRRADNGW RVTVKDTRNG GDREIQARFV 250 260 270 280 290 300 FLGAGGGALP LLQLSGIPEG KGFGGFPVSG QWLRCDNPEI VKQHQAKVYS QAEVGSPPMS 310 320 330 340 350 360 VPHLDTRVVD GKKSLLFGPY AGFSTKFLRH GSFLDLPLSV RPGNILPMLS VARDNMDLTR 370 380 390 400 410 420 YLIGQVMQSP EQRLEALRKF YPEARAEDWR LEVAGQRVQI IKKDPKKGGI LQFGTELVAA 430 440 450 460 470 480 HDGSIAALLG ASPGASVTVS IMLGLIERCF PEQARSPEWS AKLKEIFPAR EKELESDAEL 490 500 YRSVSSRCSE VLELTAKNDV QAPVNAE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Kretzschmar U., Goerisch H. Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 17933.
[2]	"Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen." Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P., Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M., Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y., Brody L.L., Coulter S.N., Folger K.R. , Kas A., Larbig K., Lim R.M., Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J., Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V. Nature 406:959-964(2000) [PubMed: 10984043] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AY129296 Genomic DNA. Translation: AAN01356.1. AE004091 Genomic DNA. Translation: AAG08028.1.
PIR	G83065.
RefSeq	NP_253330.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	881249.
GenomeReviews	Gene locus PA4640 in contig AE004091_GR.
KEGG	pae:PA4640.
Organism-specific databases
PseudoCAP	PA4640.
CMR	Search...
Phylogenomic databases
HOGENOM	Q9HVF1.
OMA	ESSNPWN.
Enzyme and pathway databases
BioCyc	PAER208964:PA4640-MON.
BRENDA	1.1.99.16. 354.
Family and domain databases
HAMAP	MF_00212. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO2_PSEAE

Accession

Primary (citable) accession number: Q9HVF1

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 2002
Last sequence update:	March 1, 2001
Last modified:	November 3, 2009
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)