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Protein

Glutamate racemase

Gene

murI

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Provides the (R)-glutamate required for cell wall biosynthesis.UniRule annotation

Catalytic activityi

L-glutamate = D-glutamate.UniRule annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei75Proton donor/acceptorUniRule annotation1
Active sitei186Proton donor/acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processCell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

BioCyciPAER208964:G1FZ6-4758-MONOMER
UniPathwayiUPA00219

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate racemaseUniRule annotation (EC:5.1.1.3UniRule annotation)
Gene namesi
Name:murIUniRule annotation
Ordered Locus Names:PA4662
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA4662

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000954971 – 265Glutamate racemaseAdd BLAST265

Proteomic databases

PaxDbiQ9HVD0

Interactioni

Protein-protein interaction databases

STRINGi208964.PA4662

Structurei

3D structure databases

ProteinModelPortaliQ9HVD0
SMRiQ9HVD0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni12 – 13Substrate bindingUniRule annotation2
Regioni44 – 45Substrate bindingUniRule annotation2
Regioni76 – 77Substrate bindingUniRule annotation2
Regioni187 – 188Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the aspartate/glutamate racemases family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105F03 Bacteria
COG0796 LUCA
HOGENOMiHOG000262395
InParanoidiQ9HVD0
KOiK01776
OMAiVYGCTHY
PhylomeDBiQ9HVD0

Family and domain databases

HAMAPiMF_00258 Glu_racemase, 1 hit
InterProiView protein in InterPro
IPR015942 Asp/Glu/hydantoin_racemase
IPR001920 Asp/Glu_race
IPR018187 Asp/Glu_racemase_AS_1
IPR033134 Asp/Glu_racemase_AS_2
IPR004391 Glu_race
PANTHERiPTHR21198:SF2 PTHR21198:SF2, 1 hit
PfamiView protein in Pfam
PF01177 Asp_Glu_race, 1 hit
SUPFAMiSSF53681 SSF53681, 2 hits
TIGRFAMsiTIGR00067 glut_race, 1 hit
PROSITEiView protein in PROSITE
PS00923 ASP_GLU_RACEMASE_1, 1 hit
PS00924 ASP_GLU_RACEMASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9HVD0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVESAAVGV FDSGVGGLSV LREIRARLPS ESLLYVADNA HVPYGEKSAE
60 70 80 90 100
YIRERCERIG DFLLEQGAKA LVLACNTATA AAAAELRERY PQVPLVAMEP
110 120 130 140 150
AVKPAAAATR NGRVGVLATT GTLKSARFAA LLDRFASDVQ VFTQPCPGLV
160 170 180 190 200
ERIEAGDLYG PQTRALLERL LAPILEQGCD TLILGCTHYP FVKPLLAELI
210 220 230 240 250
PAEMAVIDTG AAVARQLERV LSARALLASG QAATPRFWTS ALPEEMERIL
260
PILWGSPESV GKLVV
Length:265
Mass (Da):28,275
Last modified:March 1, 2001 - v1
Checksum:iB60E3D836A739CD7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA Translation: AAG08049.1
PIRiG83062
RefSeqiNP_253351.1, NC_002516.2
WP_003099300.1, NC_002516.2

Genome annotation databases

EnsemblBacteriaiAAG08049; AAG08049; PA4662
GeneIDi881345
KEGGipae:PA4662
PATRICifig|208964.12.peg.4884

Similar proteinsi

Entry informationi

Entry nameiMURI_PSEAE
AccessioniPrimary (citable) accession number: Q9HVD0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 16, 2002
Last sequence update: March 1, 2001
Last modified: March 28, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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