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Protein

Glutamate racemase

Gene

murI

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Provides the (R)-glutamate required for cell wall biosynthesis.UniRule annotation

Catalytic activityi

L-glutamate = D-glutamate.UniRule annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei75 – 751Proton donor/acceptorUniRule annotation
Active sitei186 – 1861Proton donor/acceptorUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate racemaseUniRule annotation (EC:5.1.1.3UniRule annotation)
Gene namesi
Name:murIUniRule annotation
Ordered Locus Names:PA4662
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA4662.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 265265Glutamate racemasePRO_0000095497Add
BLAST

Proteomic databases

PaxDbiQ9HVD0.

Interactioni

Protein-protein interaction databases

STRINGi208964.PA4662.

Structurei

3D structure databases

ProteinModelPortaliQ9HVD0.
SMRiQ9HVD0. Positions 8-253.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni12 – 132Substrate bindingUniRule annotation
Regioni44 – 452Substrate bindingUniRule annotation
Regioni76 – 772Substrate bindingUniRule annotation
Regioni187 – 1882Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the aspartate/glutamate racemases family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105F03. Bacteria.
COG0796. LUCA.
HOGENOMiHOG000262395.
InParanoidiQ9HVD0.
KOiK01776.
OMAiVYGCTHY.
OrthoDBiEOG6CZQQP.
PhylomeDBiQ9HVD0.

Family and domain databases

Gene3Di3.40.50.1860. 1 hit.
HAMAPiMF_00258. Glu_racemase.
InterProiIPR015942. Asp/Glu/hydantoin_racemase.
IPR001920. Asp/Glu_race.
IPR018187. Asp/Glu_racemase_AS_1.
IPR033134. Asp/Glu_racemase_AS_2.
IPR004391. Glu_race.
[Graphical view]
PfamiPF01177. Asp_Glu_race. 1 hit.
[Graphical view]
SUPFAMiSSF53681. SSF53681. 2 hits.
TIGRFAMsiTIGR00067. glut_race. 1 hit.
PROSITEiPS00923. ASP_GLU_RACEMASE_1. 1 hit.
PS00924. ASP_GLU_RACEMASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9HVD0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVESAAVGV FDSGVGGLSV LREIRARLPS ESLLYVADNA HVPYGEKSAE
60 70 80 90 100
YIRERCERIG DFLLEQGAKA LVLACNTATA AAAAELRERY PQVPLVAMEP
110 120 130 140 150
AVKPAAAATR NGRVGVLATT GTLKSARFAA LLDRFASDVQ VFTQPCPGLV
160 170 180 190 200
ERIEAGDLYG PQTRALLERL LAPILEQGCD TLILGCTHYP FVKPLLAELI
210 220 230 240 250
PAEMAVIDTG AAVARQLERV LSARALLASG QAATPRFWTS ALPEEMERIL
260
PILWGSPESV GKLVV
Length:265
Mass (Da):28,275
Last modified:March 1, 2001 - v1
Checksum:iB60E3D836A739CD7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG08049.1.
PIRiG83062.
RefSeqiNP_253351.1. NC_002516.2.
WP_003099300.1. NZ_ASJY01000743.1.

Genome annotation databases

EnsemblBacteriaiAAG08049; AAG08049; PA4662.
GeneIDi881345.
KEGGipae:PA4662.
PATRICi19844085. VBIPseAer58763_4884.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG08049.1.
PIRiG83062.
RefSeqiNP_253351.1. NC_002516.2.
WP_003099300.1. NZ_ASJY01000743.1.

3D structure databases

ProteinModelPortaliQ9HVD0.
SMRiQ9HVD0. Positions 8-253.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi208964.PA4662.

Proteomic databases

PaxDbiQ9HVD0.

Protocols and materials databases

DNASUi881345.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG08049; AAG08049; PA4662.
GeneIDi881345.
KEGGipae:PA4662.
PATRICi19844085. VBIPseAer58763_4884.

Organism-specific databases

PseudoCAPiPA4662.

Phylogenomic databases

eggNOGiENOG4105F03. Bacteria.
COG0796. LUCA.
HOGENOMiHOG000262395.
InParanoidiQ9HVD0.
KOiK01776.
OMAiVYGCTHY.
OrthoDBiEOG6CZQQP.
PhylomeDBiQ9HVD0.

Enzyme and pathway databases

UniPathwayiUPA00219.

Family and domain databases

Gene3Di3.40.50.1860. 1 hit.
HAMAPiMF_00258. Glu_racemase.
InterProiIPR015942. Asp/Glu/hydantoin_racemase.
IPR001920. Asp/Glu_race.
IPR018187. Asp/Glu_racemase_AS_1.
IPR033134. Asp/Glu_racemase_AS_2.
IPR004391. Glu_race.
[Graphical view]
PfamiPF01177. Asp_Glu_race. 1 hit.
[Graphical view]
SUPFAMiSSF53681. SSF53681. 2 hits.
TIGRFAMsiTIGR00067. glut_race. 1 hit.
PROSITEiPS00923. ASP_GLU_RACEMASE_1. 1 hit.
PS00924. ASP_GLU_RACEMASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.

Entry informationi

Entry nameiMURI_PSEAE
AccessioniPrimary (citable) accession number: Q9HVD0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 16, 2002
Last sequence update: March 1, 2001
Last modified: March 16, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.