SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9HVC3

- PTH_PSEAE

UniProt

Q9HVC3 - PTH_PSEAE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Peptidyl-tRNA hydrolase
Gene
pth, PA4672
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis By similarity.UniRule annotation

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

GO - Molecular functioni

  1. aminoacyl-tRNA hydrolase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Hydrolase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Peptidyl-tRNA hydrolase (EC:3.1.1.29)
    Short name:
    PTH
    Gene namesi
    Name:pth
    Ordered Locus Names:PA4672
    OrganismiPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
    Taxonomic identifieri208964 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
    ProteomesiUP000002438: Chromosome

    Organism-specific databases

    PseudoCAPiPA4672.

    Subcellular locationi

    Cytoplasm By similarity UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    Complete GO annotation...

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 194194Peptidyl-tRNA hydrolaseUniRule annotation
    PRO_0000187796Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer By similarity.UniRule annotation

    Protein-protein interaction databases

    STRINGi208964.PA4672.

    Structurei

    Secondary structure

    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi6 – 94
    Helixi15 – 173
    Helixi21 – 233
    Helixi24 – 3512
    Beta strandi41 – 433
    Helixi44 – 463
    Beta strandi48 – 558
    Beta strandi58 – 658
    Helixi69 – 713
    Helixi72 – 8211
    Helixi87 – 893
    Beta strandi90 – 967
    Beta strandi104 – 1096
    Helixi116 – 12510
    Beta strandi127 – 1293
    Beta strandi132 – 1376
    Helixi144 – 1463
    Helixi147 – 1515
    Helixi157 – 17216
    Helixi174 – 1796
    Helixi182 – 1898

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4DHWX-ray2.43A/B1-194[»]
    4DJJX-ray2.94A/B1-194[»]
    4ERXX-ray2.50A/B1-194[»]
    4FNOX-ray2.25A/B1-194[»]
    4FYJX-ray1.77A2-193[»]
    4JC4X-ray2.25A1-194[»]
    4QAJX-ray1.50A1-194[»]
    4QBKX-ray1.77A1-194[»]
    ProteinModelPortaliQ9HVC3.
    SMRiQ9HVC3. Positions 1-194.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PTH family.

    Phylogenomic databases

    eggNOGiCOG0193.
    HOGENOMiHOG000004796.
    KOiK01056.
    OMAiAMHRLHS.
    OrthoDBiEOG6C5RTR.
    PhylomeDBiQ9HVC3.

    Family and domain databases

    Gene3Di3.40.50.1470. 1 hit.
    HAMAPiMF_00083. Pept_tRNA_hydro_bact.
    InterProiIPR001328. Pept_tRNA_hydro.
    IPR018171. Pept_tRNA_hydro_CS.
    [Graphical view]
    PANTHERiPTHR17224. PTHR17224. 1 hit.
    PfamiPF01195. Pept_tRNA_hydro. 1 hit.
    [Graphical view]
    SUPFAMiSSF53178. SSF53178. 1 hit.
    TIGRFAMsiTIGR00447. pth. 1 hit.
    PROSITEiPS01195. PEPT_TRNA_HYDROL_1. 1 hit.
    PS01196. PEPT_TRNA_HYDROL_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9HVC3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTAVQLIVGL GNPGPEYDQT RHNAGALFVE RLAHAQGVSL VADRKYFGLV    50
    GKFSHQGKDV RLLIPTTYMN RSGQSVAALA GFFRIAPDAI LVAHDELDMP 100
    PGVAKLKTGG GHGGHNGLRD IIAQLGNQNS FHRLRLGIGH PGHSSLVSGY 150
    VLGRAPRSEQ ELLDTSIDFA LGVLPEMLAG DWTRAMQKLH SQKA 194
    Length:194
    Mass (Da):20,804
    Last modified:March 1, 2001 - v1
    Checksum:iA6E14ECBF84B61AA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE004091 Genomic DNA. Translation: AAG08059.1.
    PIRiH83060.
    RefSeqiNP_253361.1. NC_002516.2.

    Genome annotation databases

    EnsemblBacteriaiAAG08059; AAG08059; PA4672.
    GeneIDi881396.
    KEGGipae:PA4672.
    PATRICi19844107. VBIPseAer58763_4894.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE004091 Genomic DNA. Translation: AAG08059.1 .
    PIRi H83060.
    RefSeqi NP_253361.1. NC_002516.2.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4DHW X-ray 2.43 A/B 1-194 [» ]
    4DJJ X-ray 2.94 A/B 1-194 [» ]
    4ERX X-ray 2.50 A/B 1-194 [» ]
    4FNO X-ray 2.25 A/B 1-194 [» ]
    4FYJ X-ray 1.77 A 2-193 [» ]
    4JC4 X-ray 2.25 A 1-194 [» ]
    4QAJ X-ray 1.50 A 1-194 [» ]
    4QBK X-ray 1.77 A 1-194 [» ]
    ProteinModelPortali Q9HVC3.
    SMRi Q9HVC3. Positions 1-194.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 208964.PA4672.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAG08059 ; AAG08059 ; PA4672 .
    GeneIDi 881396.
    KEGGi pae:PA4672.
    PATRICi 19844107. VBIPseAer58763_4894.

    Organism-specific databases

    PseudoCAPi PA4672.

    Phylogenomic databases

    eggNOGi COG0193.
    HOGENOMi HOG000004796.
    KOi K01056.
    OMAi AMHRLHS.
    OrthoDBi EOG6C5RTR.
    PhylomeDBi Q9HVC3.

    Family and domain databases

    Gene3Di 3.40.50.1470. 1 hit.
    HAMAPi MF_00083. Pept_tRNA_hydro_bact.
    InterProi IPR001328. Pept_tRNA_hydro.
    IPR018171. Pept_tRNA_hydro_CS.
    [Graphical view ]
    PANTHERi PTHR17224. PTHR17224. 1 hit.
    Pfami PF01195. Pept_tRNA_hydro. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53178. SSF53178. 1 hit.
    TIGRFAMsi TIGR00447. pth. 1 hit.
    PROSITEi PS01195. PEPT_TRNA_HYDROL_1. 1 hit.
    PS01196. PEPT_TRNA_HYDROL_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.

    Entry informationi

    Entry nameiPTH_PSEAE
    AccessioniPrimary (citable) accession number: Q9HVC3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 1, 2001
    Last sequence update: March 1, 2001
    Last modified: September 3, 2014
    This is version 85 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

    Similar proteinsi