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Q9HV67 (G6PI_PSEAE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:PA4732
OrganismPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) [Reference proteome] [HAMAP]
Taxonomic identifier208964 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length554 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 554554Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180708

Sites

Active site3591Proton donor By similarity
Active site3901 By similarity
Active site5181 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9HV67 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: 883AB9EB7B22A307

FASTA55461,944
        10         20         30         40         50         60 
MKHHLTPLDA TQLDSWRALA AHRQELQDFR MRQAFIDDPE RFKRFSFSAC GLFLDFSKNL 

        70         80         90        100        110        120 
IRQDTIDLLV KLAEEARLSD AIRAMFDGEA INASERRPVL HTALRRPIGD KVLVDGVDVM 

       130        140        150        160        170        180 
PEVHRVLHQM TELVGYVHNG LWRGYTEKPI TDVVNIGIGG SFLGPQLVSE ALLPFAQKGV 

       190        200        210        220        230        240 
RCHYLANIDG SEFHELASRL NAETTLFIVS SKSFGTLETL KNAQAARAWY LAQGGTEEEL 

       250        260        270        280        290        300 
YRHFIAVSSN KEAAIAFGIR EENIFPMWDW VGGRYSLWSA IGLPIAMSIG ISNFKELLSG 

       310        320        330        340        350        360 
AYNMDQHFQT APFERNIPVL LGLLGVWYGD FWGANSHAIL PYDYYLRNIT DHLQQLDMES 

       370        380        390        400        410        420 
NGKSVRQDGT PVTSGTGPVI WGGVGCNGQH AYHQLLHQGT QLIPADFIVP VSSYNPVADH 

       430        440        450        460        470        480 
HQWLYANCLS QSQALMLGKS REEAEAELRA KGLPEAEVQR LAPHKVIPGN RPSNTLVVER 

       490        500        510        520        530        540 
ISARRLGALI AMYEHKVYVQ SILWGINAFD QWGVELGKEL GKGVYSRLVG SEETPAEDAS 

       550 
TQGLIDFFRG RHRG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE004091 Genomic DNA. Translation: AAG08118.1.
PIRH83053.
RefSeqNP_253420.1. NC_002516.2.

3D structure databases

ProteinModelPortalQ9HV67.
SMRQ9HV67. Positions 5-550.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING208964.PA4732.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAG08118; AAG08118; PA4732.
GeneID881638.
KEGGpae:PA4732.
PATRIC19844245. VBIPseAer58763_4957.

Organism-specific databases

PseudoCAPPA4732.

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261370.
KOK01810.
OMAISIYESN.
OrthoDBEOG64R61J.
PhylomeDBQ9HV67.

Enzyme and pathway databases

UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_PSEAE
AccessionPrimary (citable) accession number: Q9HV67
Entry history
Integrated into UniProtKB/Swiss-Prot: November 2, 2001
Last sequence update: March 1, 2001
Last modified: July 9, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways