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Protein

Uncharacterized HTH-type transcriptional regulator PA4778

Gene

PA4778

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi4 – 2320H-T-H motifPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

  • positive regulation of transcription, DNA-templated Source: PseudoCAP
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized HTH-type transcriptional regulator PA4778
Gene namesi
Ordered Locus Names:PA4778
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA4778.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 132132Uncharacterized HTH-type transcriptional regulator PA4778PRO_0000098172Add
BLAST

Proteomic databases

PaxDbiQ9HV30.

Expressioni

Gene expression databases

CollecTFiEXPREG_00001590.

Interactioni

Protein-protein interaction databases

STRINGi208964.PA4778.

Structurei

3D structure databases

ProteinModelPortaliQ9HV30.
SMRiQ9HV30. Positions 1-131.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 6969HTH merR-typePROSITE-ProRule annotationAdd
BLAST

Domaini

It contains a N-terminal DNA binding region and a C-terminal metal binding region.By similarity

Sequence similaritiesi

Contains 1 HTH merR-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4108Z6Z. Bacteria.
COG0789. LUCA.
HOGENOMiHOG000266076.
InParanoidiQ9HV30.
KOiK19591.
OMAiHTLAFIK.
PhylomeDBiQ9HV30.

Family and domain databases

InterProiIPR011789. CueR.
IPR009061. DNA-bd_dom_put.
IPR000551. MerR-type_HTH_dom.
IPR015358. Tscrpt_reg_MerR_DNA-bd.
[Graphical view]
PfamiPF00376. MerR. 1 hit.
PF09278. MerR-DNA-bind. 1 hit.
[Graphical view]
PRINTSiPR00040. HTHMERR.
SMARTiSM00422. HTH_MERR. 1 hit.
[Graphical view]
SUPFAMiSSF46955. SSF46955. 1 hit.
TIGRFAMsiTIGR02044. CueR. 1 hit.
PROSITEiPS50937. HTH_MERR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9HV30-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIGEAAKKS GLTPKMIRYY ESIELLRPAG RSASGYRHYN ENDLHTLAFI
60 70 80 90 100
RRSRDLGFSL DEVGKLLTLW QDRQRASADV KALAAQHVRE LNRKIEELST
110 120 130
LRDTLQDLVE HCQGDHRPDC PILKDLASGC CH
Length:132
Mass (Da):15,015
Last modified:March 1, 2001 - v1
Checksum:i058ECD37D200CBEA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG08164.1.
PIRiH83048.
RefSeqiNP_253466.1. NC_002516.2.
WP_003095248.1. NZ_ASJY01000750.1.

Genome annotation databases

EnsemblBacteriaiAAG08164; AAG08164; PA4778.
GeneIDi881842.
KEGGipae:PA4778.
PATRICi19844345. VBIPseAer58763_5005.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG08164.1.
PIRiH83048.
RefSeqiNP_253466.1. NC_002516.2.
WP_003095248.1. NZ_ASJY01000750.1.

3D structure databases

ProteinModelPortaliQ9HV30.
SMRiQ9HV30. Positions 1-131.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi208964.PA4778.

Proteomic databases

PaxDbiQ9HV30.

Protocols and materials databases

DNASUi881842.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG08164; AAG08164; PA4778.
GeneIDi881842.
KEGGipae:PA4778.
PATRICi19844345. VBIPseAer58763_5005.

Organism-specific databases

PseudoCAPiPA4778.

Phylogenomic databases

eggNOGiENOG4108Z6Z. Bacteria.
COG0789. LUCA.
HOGENOMiHOG000266076.
InParanoidiQ9HV30.
KOiK19591.
OMAiHTLAFIK.
PhylomeDBiQ9HV30.

Gene expression databases

CollecTFiEXPREG_00001590.

Family and domain databases

InterProiIPR011789. CueR.
IPR009061. DNA-bd_dom_put.
IPR000551. MerR-type_HTH_dom.
IPR015358. Tscrpt_reg_MerR_DNA-bd.
[Graphical view]
PfamiPF00376. MerR. 1 hit.
PF09278. MerR-DNA-bind. 1 hit.
[Graphical view]
PRINTSiPR00040. HTHMERR.
SMARTiSM00422. HTH_MERR. 1 hit.
[Graphical view]
SUPFAMiSSF46955. SSF46955. 1 hit.
TIGRFAMsiTIGR02044. CueR. 1 hit.
PROSITEiPS50937. HTH_MERR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiY4778_PSEAE
AccessioniPrimary (citable) accession number: Q9HV30
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 3, 2002
Last sequence update: March 1, 2001
Last modified: September 7, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.