Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Uncharacterized protein

Gene

PA4794

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei29 – 291CoenzymeACombined sources
Binding sitei121 – 1211CoenzymeACombined sources

GO - Molecular functioni

  1. N-acetyltransferase activity Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Ordered Locus Names:PA4794Imported
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)Imported
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA4794.

Interactioni

Protein-protein interaction databases

STRINGi208964.PA4794.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3KKWX-ray1.41A1-160[»]
3PGPX-ray1.42A1-160[»]
4KLVX-ray1.30A1-160[»]
4KLWX-ray1.30A1-160[»]
4KORX-ray1.25A1-160[»]
4KOSX-ray1.55A1-160[»]
4KOTX-ray1.55A1-160[»]
4KOUX-ray1.60A1-160[»]
4KOVX-ray1.60A1-160[»]
4KOWX-ray1.45A1-160[»]
4KOXX-ray1.80A1-160[»]
4KOYX-ray1.40A1-160[»]
4KUAX-ray1.50A1-160[»]
4KUBX-ray1.57A1-160[»]
4L89X-ray1.60A1-160[»]
4L8AX-ray1.20A1-160[»]
4M3SX-ray1.30A1-160[»]
4OADX-ray1.45A1-160[»]
4OAEX-ray1.25A1-160[»]
ProteinModelPortaliQ9HV14.
SMRiQ9HV14. Positions 1-159.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9HV14.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni81 – 833CoenzymeA bindingCombined sources
Regioni89 – 946CoenzymeA bindingCombined sources
Regioni126 – 1305CoenzymeA bindingCombined sources

Phylogenomic databases

HOGENOMiHOG000133531.
OMAiELFYMFP.
OrthoDBiEOG6DC6JX.
PhylomeDBiQ9HV14.

Family and domain databases

Gene3Di3.40.630.30. 1 hit.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR000182. GNAT_dom.
[Graphical view]
PfamiPF00583. Acetyltransf_1. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
PROSITEiPS51186. GNAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9HV14-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQLSHRPAET GDLETVAGFP QDRDELFYCY PKAIWPFSVA QLAAAIAERR
60 70 80 90 100
GSTVAVHDGQ VLGFANFYQW QHGDFCALGN MMVAPAARGL GVARYLIGVM
110 120 130 140 150
ENLAREQYKA RLMKISCFNA NAAGLLLYTQ LGYQPRAIAE RHDPDGRRVA
160
LIQMDKPLEP
Length:160
Mass (Da):17,785
Last modified:March 1, 2001 - v1
Checksum:i6DE397F9A25DF686
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG08180.1.
PIRiH83047.
RefSeqiNP_253482.1. NC_002516.2.

Genome annotation databases

EnsemblBacteriaiAAG08180; AAG08180; PA4794.
GeneIDi880440.
KEGGipae:PA4794.
PATRICi19844379. VBIPseAer58763_5022.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG08180.1.
PIRiH83047.
RefSeqiNP_253482.1. NC_002516.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3KKWX-ray1.41A1-160[»]
3PGPX-ray1.42A1-160[»]
4KLVX-ray1.30A1-160[»]
4KLWX-ray1.30A1-160[»]
4KORX-ray1.25A1-160[»]
4KOSX-ray1.55A1-160[»]
4KOTX-ray1.55A1-160[»]
4KOUX-ray1.60A1-160[»]
4KOVX-ray1.60A1-160[»]
4KOWX-ray1.45A1-160[»]
4KOXX-ray1.80A1-160[»]
4KOYX-ray1.40A1-160[»]
4KUAX-ray1.50A1-160[»]
4KUBX-ray1.57A1-160[»]
4L89X-ray1.60A1-160[»]
4L8AX-ray1.20A1-160[»]
4M3SX-ray1.30A1-160[»]
4OADX-ray1.45A1-160[»]
4OAEX-ray1.25A1-160[»]
ProteinModelPortaliQ9HV14.
SMRiQ9HV14. Positions 1-159.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi208964.PA4794.

Protocols and materials databases

DNASUi880440.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG08180; AAG08180; PA4794.
GeneIDi880440.
KEGGipae:PA4794.
PATRICi19844379. VBIPseAer58763_5022.

Organism-specific databases

PseudoCAPiPA4794.

Phylogenomic databases

HOGENOMiHOG000133531.
OMAiELFYMFP.
OrthoDBiEOG6DC6JX.
PhylomeDBiQ9HV14.

Miscellaneous databases

EvolutionaryTraceiQ9HV14.

Family and domain databases

Gene3Di3.40.630.30. 1 hit.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR000182. GNAT_dom.
[Graphical view]
PfamiPF00583. Acetyltransf_1. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
PROSITEiPS51186. GNAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228Imported.
  2. "Crystal structure of His-tagged form of PA4794 protein."
    Majorek K.A., Chruszcz M., Joachimiak A., Minor W.
    Submitted (OCT-2009) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.41 ANGSTROMS).
  3. "Structural, functional, and inhibition studies of a Gcn5-related N-acetyltransferase (GNAT) superfamily protein PA4794: a new C-terminal lysine protein acetyltransferase from pseudomonas aeruginosa."
    Majorek K.A., Kuhn M.L., Chruszcz M., Anderson W.F., Minor W.
    J. Biol. Chem. 288:30223-30235(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.20 ANGSTROMS) IN COMPLEX WITH COENZYMEA.
  4. "Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with HEPES."
    Majorek K.A., Kuhn M.L., Chruszcz M., Anderson W.F., Minor W.
    Submitted (JUL-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.30 ANGSTROMS).
  5. "Crystal structure of a GNAT superfamily acetyltransferase PA4794 C29A/C117A/Y128A mutant in complex with chloramphenicol."
    Majorek K.A., Chruszcz M., Joachimiak A., Minor W.
    Submitted (DEC-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.25 ANGSTROMS).
  6. "Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with chloramphenicol."
    Majorek K.A., Niedzialkowska E., Chruszcz M., Joachimiak A., Minor W.
    Submitted (DEC-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.45 ANGSTROMS).

Entry informationi

Entry nameiQ9HV14_PSEAE
AccessioniPrimary (citable) accession number: Q9HV14
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: January 7, 2015
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.