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Q9HV14 (Q9HV14_PSEAE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length160 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region8 – 103Sulfate 2 binding PDB 4KLV
Region50 – 512Sulfate 4 binding PDB 4KOU PDB 4KOV PDB 4KOW PDB 4KLV PDB 4KOR PDB 4KOS PDB 4KOT PDB 4KOX PDB 4KOY PDB 4KUA PDB 4OAD PDB 4OAE
Region80 – 812Cefoxitin binding PDB 4KOW
Region81 – 833Coenzyme A binding
Region89 – 946Coenzyme A binding
Region90 – 945Sulfate 8 binding PDB 4KOU PDB 4KOV PDB 4KOW PDB 3KKW PDB 4KLV PDB 4KLW PDB 4KOR PDB 4KOS PDB 4KOT PDB 4KOX PDB 4KOY PDB 4KUA PDB 4L8A PDB 4OAD PDB 4OAE
Region118 – 1214Chloride 1 binding PDB 4M3S
Region126 – 1305Coenzyme A binding
Region134 – 1363Sulfate 9 binding PDB 4KOU PDB 4KOT PDB 4KOX PDB 4OAE
Region141 – 1422Sulfate 11 binding PDB 4KOU PDB 4KOV PDB 4KLV PDB 4KLW PDB 4KOR PDB 4KOS PDB 4KOT PDB 4KOX PDB 4KUA PDB 4M3S PDB 4OAD PDB 4OAE

Sites

Binding site51Sulfate 1 PDB 4KLW
Binding site201Chloramphenicol 2 PDB 4OAD PDB 4OAE
Binding site291Coenzyme A PDB 4L89
Binding site381Sulfate 3 PDB 4KLV PDB 4KUA
Binding site491Cefoxitin PDB 4KOW
Binding site501Sulfate 6 (covalent) PDB 4OAD PDB 4OAE
Binding site511Chloride 3; via amide nitrogen PDB 4M3S
Binding site511Sulfate 5; via amide nitrogen PDB 4KLW
Binding site601Sulfate 7 PDB 4L8A
Binding site681Cefoxitin PDB 4KOW
Binding site861Chloramphenicol 1; via carbonyl oxygen PDB 4OAD
Binding site861Chloride 4; via amide nitrogen PDB 4M3S
Binding site881Chloramphenicol 2 PDB 4OAD PDB 4OAE
Binding site941Chloride 3; via amide nitrogen
Binding site941Chloride 5; via amide nitrogen PDB 4M3S
Binding site1021Sulfate 1 PDB 4KLW
Binding site1161Cefoxitin; via carbonyl oxygen PDB 4KOW
Binding site1211Chloramphenicol 2 PDB 4OAD PDB 4OAE
Binding site1211Coenzyme A
Binding site1411Cefoxitin PDB 4KOW
Binding site1411Sulfate 10 PDB 4KLV PDB 4M3S PDB 4L8A PDB 4OAE
Binding site1411Sulfate 12 PDB 4KOU PDB 4KOW PDB 3KKW PDB 4KOS
Binding site1411Sulfate 2
Binding site1421Sulfate 3
Binding site1531Sulfate 10 PDB 4KLV PDB 4M3S PDB 4L8A PDB 4OAE
Binding site1531Sulfate 12 PDB 4KOU PDB 4KOW PDB 4KOS
Binding site1531Sulfate 2

Sequences

Sequence LengthMass (Da)Tools
Q9HV14 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: 6DE397F9A25DF686

FASTA16017,785
        10         20         30         40         50         60 
MQLSHRPAET GDLETVAGFP QDRDELFYCY PKAIWPFSVA QLAAAIAERR GSTVAVHDGQ 

        70         80         90        100        110        120 
VLGFANFYQW QHGDFCALGN MMVAPAARGL GVARYLIGVM ENLAREQYKA RLMKISCFNA 

       130        140        150        160 
NAAGLLLYTQ LGYQPRAIAE RHDPDGRRVA LIQMDKPLEP 

« Hide

References

« Hide 'large scale' references
[1]"Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen."
Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P., Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M., Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y., Brody L.L., Coulter S.N., Folger K.R. expand/collapse author list , Kas A., Larbig K., Lim R.M., Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J., Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.
Nature 406:959-964(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.
[2]"Crystal structure of His-tagged form of PA4794 protein."
Majorek K.A., Chruszcz M., Joachimiak A., Minor W.
Submitted (NOV-2009) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.41 ANGSTROMS) IN COMPLEX WITH SULFATE.
[3]"Structural, functional, and inhibition studies of a Gcn5-related N-acetyltransferase (GNAT) superfamily protein PA4794: a new C-terminal lysine protein acetyltransferase from pseudomonas aeruginosa."
Majorek K.A., Kuhn M.L., Chruszcz M., Anderson W.F., Minor W.
J. Biol. Chem. 288:30223-30235(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.20 ANGSTROMS) IN COMPLEX WITH CEFOXITIN; COENZYME A AND SULFATE.
[4]"Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with HEPES."
Majorek K.A., Kuhn M.L., Chruszcz M., Anderson W.F., Minor W.
Submitted (AUG-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.30 ANGSTROMS) IN COMPLEX WITH CHLORIDE AND SULFATE.
[5]"Crystal structure of a GNAT superfamily acetyltransferase PA4794 C29A/C117A/Y128A mutant in complex with chloramphenicol."
Majorek K.A., Chruszcz M., Joachimiak A., Minor W.
Submitted (JAN-2014) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.25 ANGSTROMS) IN COMPLEX WITH CHLORAMPHENICOL AND SULFATE.
[6]"Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with chloramphenicol."
Majorek K.A., Niedzialkowska E., Chruszcz M., Joachimiak A., Minor W.
Submitted (JAN-2014) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.45 ANGSTROMS) IN COMPLEX WITH CHLORAMPHENICOL AND SULFATE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE004091 Genomic DNA. Translation: AAG08180.1.
PIRH83047.
RefSeqNP_253482.1. NC_002516.2.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3KKWX-ray1.41A1-160[»]
3PGPX-ray1.42A1-160[»]
4KLVX-ray1.30A1-160[»]
4KLWX-ray1.30A1-160[»]
4KORX-ray1.25A1-160[»]
4KOSX-ray1.55A1-160[»]
4KOTX-ray1.55A1-160[»]
4KOUX-ray1.60A1-160[»]
4KOVX-ray1.60A1-160[»]
4KOWX-ray1.45A1-160[»]
4KOXX-ray1.80A1-160[»]
4KOYX-ray1.40A1-160[»]
4KUAX-ray1.50A1-160[»]
4KUBX-ray1.57A1-160[»]
4L89X-ray1.60A1-160[»]
4L8AX-ray1.20A1-160[»]
4M3SX-ray1.30A1-160[»]
4OADX-ray1.45A1-160[»]
4OAEX-ray1.25A1-160[»]
ProteinModelPortalQ9HV14.
SMRQ9HV14. Positions 1-159.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING208964.PA4794.

Protocols and materials databases

DNASU880440.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID880440.
KEGGpae:PA4794.
PATRIC19844379. VBIPseAer58763_5022.

Organism-specific databases

PseudoCAPPA4794.

Phylogenomic databases

HOGENOMHOG000133531.
OMAELFYMFP.
OrthoDBEOG6DC6JX.
ProtClustDBCLSK868904.

Family and domain databases

Gene3D3.40.630.30. 1 hit.
InterProIPR016181. Acyl_CoA_acyltransferase.
IPR000182. GNAT_dom.
[Graphical view]
PfamPF00583. Acetyltransf_1. 1 hit.
[Graphical view]
SUPFAMSSF55729. SSF55729. 1 hit.
PROSITEPS51186. GNAT. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ9HV14.

Entry information

Entry nameQ9HV14_PSEAE
AccessionPrimary (citable) accession number: Q9HV14
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: April 16, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)