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Q9HUP4 (PNCB1_PSEAE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase 1

Short name=NAPRTase 1
EC=6.3.4.21
Gene names
Name:pncB1
Ordered Locus Names:PA4919
OrganismPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) [Reference proteome] [HAMAP]
Taxonomic identifier208964 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length399 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 399399Nicotinate phosphoribosyltransferase 1 HAMAP-Rule MF_00570
PRO_0000205837

Sequences

Sequence LengthMass (Da)Tools
Q9HUP4 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: 49B2266CF47346DE

FASTA39946,095
        10         20         30         40         50         60 
MAESVFAERI VQNLLDTDFY KLTMMQAVLH NYPNAEVEWE FRCRNAEDLR PYLAEIRYQI 

        70         80         90        100        110        120 
ERLAEVEVTA DQLAFLERIP FMKPDFIRFL SLFRFNLRYV HTGIEDGQLA IRLRGPWLHV 

       130        140        150        160        170        180 
ILFEVPLLAI VSEVRNRYRY REVVLEQVGE QLYRKLDWLS AQASSEELAE FQVADFGTRR 

       190        200        210        220        230        240 
RFSYRTQEEV VHILKRDFPG RFVGTSNVHL AREYDLKPIG TMAHEWLMAH QQLGPRLVDS 

       250        260        270        280        290        300 
QQAALDCWVR EYRGQLGIAL TDCITMDAFL DDFDLYFAKL FDGLRHDSGD PLAWAEKAIA 

       310        320        330        340        350        360 
HYRRLGIDPL SKTLVFSDGL DMPKALQLFR ALRGKINVSF GIGTNLTCDI PGVEPMNIVL 

       370        380        390 
KMTACNGHPV AKISDAPGKT QCRDENFVAY LRHVFNVPA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE004091 Genomic DNA. Translation: AAG08304.1.
PIRE83030.
RefSeqNP_253606.1. NC_002516.2.

3D structure databases

ProteinModelPortalQ9HUP4.
SMRQ9HUP4. Positions 1-397.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING208964.PA4919.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAG08304; AAG08304; PA4919.
GeneID882212.
KEGGpae:PA4919.
PATRIC19844642. VBIPseAer58763_5152.

Organism-specific databases

PseudoCAPPA4919.

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284928.
KOK00763.
OMAECWVREY.
OrthoDBEOG6X10XB.
PhylomeDBQ9HUP4.

Enzyme and pathway databases

UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB1_PSEAE
AccessionPrimary (citable) accession number: Q9HUP4
Entry history
Integrated into UniProtKB/Swiss-Prot: July 11, 2002
Last sequence update: March 1, 2001
Last modified: July 9, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways