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Q9HUM0 (HFQ_PSEAE) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Protein hfq
Gene names
Name:hfq
Ordered Locus Names:PA4944
OrganismPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Taxonomic identifier208964 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length82 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs By similarity. HAMAP MF_00436

Subunit structure

Homohexamer By similarity. HAMAP MF_00436

Sequence similarities

Belongs to the hfq family.

Ontologies

Keywords
   Biological processStress response
   LigandRNA-binding
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological processregulation of transcription, DNA-dependent

Inferred from electronic annotation. Source: InterPro

response to stress

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 8282Protein hfq HAMAP MF_00436
PRO_0000095656

Secondary structure

1 ............. 82
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q9HUM0 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: 1153661DC4C5AE2F

FASTA829,104
        10         20         30         40         50         60 
MSKGHSLQDP YLNTLRKERV PVSIYLVNGI KLQGQIESFD QFVILLKNTV SQMVYKHAIS 

        70         80 
TVVPSRPVRL PSGDQPAEPG NA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE004091 Genomic DNA. Translation: AAG08329.1.
PIRD83028.
RefSeqNP_253631.1. NC_002516.2.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1U1SX-ray1.60A/B/C/D/E/F1-82[»]
1U1TX-ray1.90A/B/C/D/E/F1-82[»]
3INZX-ray1.70A/B/C/D/E/F1-82[»]
3M4GX-ray2.05A/B/C/D/E/F/G/H/I/J/K/L1-82[»]
ProteinModelPortalQ9HUM0.
SMRQ9HUM0. Positions 3-71.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID878015.
GenomeReviewsGene locus PA4944 in contig AE004091_GR.
KEGGpae:PA4944.
PATRIC19844696. VBIPseAer58763_5177.

Organism-specific databases

PseudoCAPPA4944.

Phylogenomic databases

HOGENOMHBG645207.
OMAPYLNVLR.
ProtClustDBPRK00395.

Enzyme and pathway databases

BioCycPAER208964:PA4944-MONOMER.

Family and domain databases

HAMAPMF_00436. Lsm_Hfq.
[Tree]
InterProIPR005001. Hfq.
IPR010920. LSM-related_domain.
IPR001163. LSM_domain.
[Graphical view]
KOK03666.
PfamPF01423. LSM. 1 hit.
[Graphical view]
SUPFAMSSF50182. Sm_like_riboprot. 1 hit.
TIGRFAMsTIGR02383. Hfq. 1 hit.
ProtoNetSearch...

Entry information

Entry nameHFQ_PSEAE
AccessionPrimary (citable) accession number: Q9HUM0
Entry history
Integrated into UniProtKB/Swiss-Prot: August 29, 2001
Last sequence update: March 1, 2001
Last modified: January 25, 2012
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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