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Protein
Submitted name:

Uncharacterized protein

Gene

PA4992

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei29 – 291NADPCombined sources
Binding sitei255 – 2551NADPCombined sources
Binding sitei259 – 2591NADPCombined sources

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi250 – 2512NADPCombined sources

GO - Molecular functioni

  1. nucleotide binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Ligandi

NADPCombined sources, Nucleotide-bindingCombined sources

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Ordered Locus Names:PA4992Imported
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)Imported
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA4992.

Interactioni

Protein-protein interaction databases

STRINGi208964.PA4992.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4EXAX-ray2.80A/B/C/D/E/F1-270[»]
4EXBX-ray2.75A/B/C/D/E/F1-270[»]
ProteinModelPortaliQ9HUH3.
SMRiQ9HUH3. Positions 1-268.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000250281.
InParanoidiQ9HUH3.
OMAiVYQTLAE.
OrthoDBiEOG69WFJ0.
PhylomeDBiQ9HUH3.

Family and domain databases

Gene3Di3.20.20.100. 1 hit.
InterProiIPR001395. Aldo/ket_red.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
PANTHERiPTHR11732. PTHR11732. 1 hit.
PfamiPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
SUPFAMiSSF51430. SSF51430. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9HUH3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIRDTLHDLH RPLGDTGLAV SPLGLGTVKF GRDQGVKYPS GFTIPDDREA
60 70 80 90 100
ADLLALARDL GINLIDTAPA YGRSEERLGP LLRGQREHWV IVSKVGEEFV
110 120 130 140 150
DGQSVFDFSA AHTRRSVERS LKRLETDRIE LVLVHSDGND LDILENSEVY
160 170 180 190 200
PTLAALKREG LIGAYGLSGK TVEGGLRALR EGDCAMVTYN LNERAERPVI
210 220 230 240 250
EYAAAHAKGI LVKKALASGH ACLGAGQDPV RASFELVFDQ PGVAAAIVGT
260 270
INPLHLAHNV AMAAQALKKA
Length:270
Mass (Da):29,030
Last modified:February 28, 2001 - v1
Checksum:i5C29A86033691A4D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG08377.1.
PIRiE83021.
RefSeqiNP_253679.1. NC_002516.2.

Genome annotation databases

EnsemblBacteriaiAAG08377; AAG08377; PA4992.
GeneIDi880167.
KEGGipae:PA4992.
PATRICi19844807. VBIPseAer58763_5232.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG08377.1.
PIRiE83021.
RefSeqiNP_253679.1. NC_002516.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4EXAX-ray2.80A/B/C/D/E/F1-270[»]
4EXBX-ray2.75A/B/C/D/E/F1-270[»]
ProteinModelPortaliQ9HUH3.
SMRiQ9HUH3. Positions 1-268.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi208964.PA4992.

Protocols and materials databases

DNASUi880167.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG08377; AAG08377; PA4992.
GeneIDi880167.
KEGGipae:PA4992.
PATRICi19844807. VBIPseAer58763_5232.

Organism-specific databases

PseudoCAPiPA4992.

Phylogenomic databases

HOGENOMiHOG000250281.
InParanoidiQ9HUH3.
OMAiVYQTLAE.
OrthoDBiEOG69WFJ0.
PhylomeDBiQ9HUH3.

Family and domain databases

Gene3Di3.20.20.100. 1 hit.
InterProiIPR001395. Aldo/ket_red.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
PANTHERiPTHR11732. PTHR11732. 1 hit.
PfamiPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
SUPFAMiSSF51430. SSF51430. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228Imported.
  2. "The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery."
    Moynie L., Schnell R., McMahon S.A., Sandalova T., Boulkerou W.A., Schmidberger J.W., Alphey M., Cukier C., Duthie F., Kopec J., Liu H., Jacewicz A., Hunter W.N., Naismith J.H., Schneider G.
    Acta Crystallogr. F 69:25-34(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.75 ANGSTROMS) IN COMPLEX WITH NADP.

Entry informationi

Entry nameiQ9HUH3_PSEAE
AccessioniPrimary (citable) accession number: Q9HUH3
Entry historyi
Integrated into UniProtKB/TrEMBL: February 28, 2001
Last sequence update: February 28, 2001
Last modified: January 6, 2015
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.