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Protein

Sec-independent protein translocase protein TatB

Gene

tatB

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Translocation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Sec-independent protein translocase protein TatBUniRule annotation
Gene namesi
Name:tatBUniRule annotation
Ordered Locus Names:PA5069
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA5069.

Subcellular locationi

  • Cell inner membrane UniRule annotation; Single-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei1 – 2121HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 141141Sec-independent protein translocase protein TatBPRO_0000192665Add
BLAST

Proteomic databases

PaxDbiQ9HUB4.

Interactioni

Subunit structurei

The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.UniRule annotation

Protein-protein interaction databases

STRINGi208964.PA5069.

Structurei

3D structure databases

ProteinModelPortaliQ9HUB4.
SMRiQ9HUB4. Positions 1-82.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TatB family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG41067S4. Bacteria.
ENOG410XUF0. LUCA.
HOGENOMiHOG000245368.
KOiK03117.
OMAiKRILNPM.
OrthoDBiEOG6WQD34.

Family and domain databases

HAMAPiMF_00237. TatB.
InterProiIPR003369. TatA/B/E.
IPR018448. TatB.
IPR003998. TatB-like.
[Graphical view]
PfamiPF02416. MttA_Hcf106. 1 hit.
[Graphical view]
PRINTSiPR01506. TATBPROTEIN.
TIGRFAMsiTIGR01410. tatB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9HUB4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFGISFSELL LVGLVALLVL GPERLPGAAR TAGLWIGRLK RSFNTIKQEV
60 70 80 90 100
EREIGADEIR RQLHNEHILS MEREAQKLLA PLTGQNPPQE TPPPAAESPA
110 120 130 140
PSVPTPPPTS TPAVPPADAA APPAVAASTP PSPPSETPRN P
Length:141
Mass (Da):14,864
Last modified:March 1, 2001 - v1
Checksum:iEA51576FED3C64B4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG08454.1.
PIRiH83011.
RefSeqiNP_253756.1. NC_002516.2.
WP_003115042.1. NC_002516.2.

Genome annotation databases

EnsemblBacteriaiAAG08454; AAG08454; PA5069.
GeneIDi879670.
KEGGipae:PA5069.
PATRICi19844969. VBIPseAer58763_5313.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004091 Genomic DNA. Translation: AAG08454.1.
PIRiH83011.
RefSeqiNP_253756.1. NC_002516.2.
WP_003115042.1. NC_002516.2.

3D structure databases

ProteinModelPortaliQ9HUB4.
SMRiQ9HUB4. Positions 1-82.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi208964.PA5069.

Proteomic databases

PaxDbiQ9HUB4.

Protocols and materials databases

DNASUi879670.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG08454; AAG08454; PA5069.
GeneIDi879670.
KEGGipae:PA5069.
PATRICi19844969. VBIPseAer58763_5313.

Organism-specific databases

PseudoCAPiPA5069.

Phylogenomic databases

eggNOGiENOG41067S4. Bacteria.
ENOG410XUF0. LUCA.
HOGENOMiHOG000245368.
KOiK03117.
OMAiKRILNPM.
OrthoDBiEOG6WQD34.

Family and domain databases

HAMAPiMF_00237. TatB.
InterProiIPR003369. TatA/B/E.
IPR018448. TatB.
IPR003998. TatB-like.
[Graphical view]
PfamiPF02416. MttA_Hcf106. 1 hit.
[Graphical view]
PRINTSiPR01506. TATBPROTEIN.
TIGRFAMsiTIGR01410. tatB. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.

Entry informationi

Entry nameiTATB_PSEAE
AccessioniPrimary (citable) accession number: Q9HUB4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: March 1, 2001
Last modified: November 11, 2015
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.