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Q9HTM2 (KGUA_PSEAE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Guanylate kinase

EC=2.7.4.8
Alternative name(s):
GMP kinase
Gene names
Name:gmk
Ordered Locus Names:PA5336
OrganismPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) [Reference proteome] [HAMAP]
Taxonomic identifier208964 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length203 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Essential for recycling GMP and indirectly, cGMP By similarity. HAMAP-Rule MF_00328

Catalytic activity

ATP + GMP = ADP + GDP. HAMAP-Rule MF_00328

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00328.

Sequence similarities

Belongs to the guanylate kinase family.

Contains 1 guanylate kinase-like domain.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processpurine nucleotide metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

guanylate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 203203Guanylate kinase HAMAP-Rule MF_00328
PRO_0000170587

Regions

Domain3 – 181179Guanylate kinase-like
Nucleotide binding10 – 178ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9HTM2 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: DE35644BBE88623A

FASTA20323,102
        10         20         30         40         50         60 
MSGTLYIVSA PSGAGKTSLV KALLDAAPEV RVSVSHTTRG MRPGEVDGVN YHFTSREEFL 

        70         80         90        100        110        120 
AMLERNEFLE HAEVFGNLYG TSQRWVEKTL AEGLDLILEI DWQGAQQVRR LMPEAQSIFI 

       130        140        150        160        170        180 
LPPSQEALRQ RLTNRGQDSD EVIERRMREA VSEMSHYVEY DHLVINDDFA HALDDLKAIF 

       190        200 
RARQLRQDAQ QQRHAELLGR LLA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE004091 Genomic DNA. Translation: AAG08721.1.
PIRF82978.
RefSeqNP_254023.1. NC_002516.2.

3D structure databases

ProteinModelPortalQ9HTM2.
SMRQ9HTM2. Positions 3-203.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING208964.PA5336.

Protocols and materials databases

DNASU878047.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID878047.
KEGGpae:PA5336.
PATRIC19845529. VBIPseAer58763_5591.

Organism-specific databases

PseudoCAPPA5336.

Phylogenomic databases

eggNOGCOG0194.
HOGENOMHOG000037638.
KOK00942.
OMAIFLMPPD.
OrthoDBEOG6CP410.
ProtClustDBPRK00300.

Family and domain databases

Gene3D3.40.50.300. 2 hits.
HAMAPMF_00328. Guanylate_kinase.
InterProIPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF00625. Guanylate_kin. 1 hit.
[Graphical view]
SMARTSM00072. GuKc. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR03263. guanyl_kin. 1 hit.
PROSITEPS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameKGUA_PSEAE
AccessionPrimary (citable) accession number: Q9HTM2
Entry history
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: March 1, 2001
Last modified: April 16, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families