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Q9HSC1 (TRPC_HALSA) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Indole-3-glycerol phosphate synthase

Short name=IGPS
EC=4.1.1.48
Gene names
Name:trpC
Ordered Locus Names:VNG_0305G
OrganismHalobacterium salinarium (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Taxonomic identifier64091 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalobacterium

Protein attributes

Sequence length251 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. HAMAP MF_00134_A

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. HAMAP MF_00134_A

Sequence similarities

Belongs to the TrpC family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 251251Indole-3-glycerol phosphate synthase HAMAP MF_00134_A
PRO_0000154290

Sequences

Sequence LengthMass (Da)Tools
Q9HSC1 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: DD3B8FE21E37EC83

FASTA25126,053
        10         20         30         40         50         60 
MDDSSSLASP VQSILAAARR RDPPTRRCTV SARSLPAALH SAAADGRTPI IAEVKPTSPT 

        70         80         90        100        110        120 
TDTEHSGDPA ELAREMVAGG AAAVSVLTEP HHFDGSTDAL RAIRDAVDVP VLRKDFLLTE 

       130        140        150        160        170        180 
PQLDAVAADA VLLIARFLGD DLGDMLAAAR DRGFQALVEV HSPRELARAV DADADIIGVN 

       190        200        210        220        230        240 
NRDLTALTVD LDTFGAVAPE APADVTLVAE SGIATPTDAR TMRAAGADGL LVGSAIMDGP 

       250 
VRDTTRRLVT A 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE004437 Genomic DNA. Translation: AAG18886.1.
PIRB84190.
RefSeqNP_279406.1. NC_002607.1.

3D structure databases

ProteinModelPortalQ9HSC1.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1447194.
GenomeReviewsGene locus VNG_0305G in contig AE004437_GR.
KEGGhal:VNG0305G.
NMPDRfig|64091.1.peg.419.

Phylogenomic databases

HOGENOMHBG540956.
OMAFETDINT.
PhylomeDBQ9HSC1.
ProtClustDBCLSK511041.

Enzyme and pathway databases

BioCycHSP64091:VNG0305G-MONOMER.

Family and domain databases

HAMAPMF_00134_A. IGPS_A.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR013798. Indole-3-glycerol_P_synth.
IPR001468. Indole-3-GlycerolPSynthase_CS.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01609.
PfamPF00218. IGPS. 1 hit.
[Graphical view]
SUPFAMSSF51366. RibP_bind_barrel. 1 hit.
PROSITEPS00614. IGPS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTRPC_HALSA
AccessionPrimary (citable) accession number: Q9HSC1
Entry history
Integrated into UniProtKB/Swiss-Prot: June 6, 2002
Last sequence update: March 1, 2001
Last modified: December 14, 2011
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families