Q9HSC1 (TRPC_HALSA) Reviewed, UniProtKB/Swiss-Prot
Last modified
December 14, 2011.
Version 64.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Indole-3-glycerol phosphate synthase Short name=IGPS EC=4.1.1.48 | ||||
| Gene names |
| ||||
| Organism | Halobacterium salinarium (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium) | ||||
| Taxonomic identifier | 64091 [NCBI] | ||||
| Taxonomic lineage | Archaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Halobacterium |
Protein attributes
| Sequence length | 251 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. HAMAP MF_00134_A |
| Pathway | Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. HAMAP MF_00134_A |
| Sequence similarities | Belongs to the TrpC family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis |
| Molecular function | Decarboxylase Lyase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | tryptophan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | indole-3-glycerol-phosphate synthase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 251 | 251 | Indole-3-glycerol phosphate synthase HAMAP MF_00134_A | PRO_0000154290 | |||
Sequences
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References
| [1] | "Genome sequence of Halobacterium species NRC-1." Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D., Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D., Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K. DasSarma S.Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000) [PubMed: 11016950] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700922 / JCM 11081 / NRC-1. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AE004437 Genomic DNA. Translation: AAG18886.1. |
| PIR | B84190. |
| RefSeq | NP_279406.1. NC_002607.1. |
3D structure databases | |
| ProteinModelPortal | Q9HSC1. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 1447194. |
| GenomeReviews | Gene locus VNG_0305G in contig AE004437_GR. |
| KEGG | hal:VNG0305G. |
| NMPDR | fig|64091.1.peg.419. |
Phylogenomic databases | |
| HOGENOM | HBG540956. |
| OMA | FETDINT. |
| PhylomeDB | Q9HSC1. |
| ProtClustDB | CLSK511041. |
Enzyme and pathway databases | |
| BioCyc | HSP64091:VNG0305G-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00134_A. IGPS_A. [Tree] |
| InterPro | IPR013785. Aldolase_TIM. IPR013798. Indole-3-glycerol_P_synth. IPR001468. Indole-3-GlycerolPSynthase_CS. IPR011060. RibuloseP-bd_barrel. [Graphical view] |
| Gene3D | G3DSA:3.20.20.70. Aldolase_TIM. 1 hit. |
| KO | K01609. |
| Pfam | PF00218. IGPS. 1 hit. [Graphical view] |
| SUPFAM | SSF51366. RibP_bind_barrel. 1 hit. |
| PROSITE | PS00614. IGPS. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | TRPC_HALSA | ||||||||
| Accession | Primary (citable) accession number: Q9HSC1 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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