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Protein

Cell division protein FtsZ 1

Gene

ftsZ1

Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei179GTPUniRule annotation1
Binding sitei183GTPUniRule annotation1
Binding sitei226GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi61 – 65GTPUniRule annotation5
Nucleotide bindingi148 – 150GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, Septation
LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZ 1UniRule annotation
Gene namesi
Name:ftsZ1UniRule annotation
Ordered Locus Names:VNG_0376G
OrganismiHalobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Taxonomic identifieri64091 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalobacterium
Proteomesi
  • UP000000554 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation
  • Note: Assembles at midcell at the inner surface of the cytoplasmic membrane.UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004142391 – 396Cell division protein FtsZ 1Add BLAST396

Proteomic databases

PaxDbiQ9HS71

Interactioni

Subunit structurei

Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.UniRule annotation

Protein-protein interaction databases

STRINGi64091.VNG0376G

Structurei

3D structure databases

ProteinModelPortaliQ9HS71
SMRiQ9HS71
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG02201 Archaea
COG0206 LUCA
InParanoidiQ9HS71
KOiK03531
OMAiMRAVKGI
OrthoDBiPOG093Z0942
PhylomeDBiQ9HS71

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9HS71-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSIVQDAID EAEESEDSAS EPADVAGGGG DTVPTGTMTD NELEDVLQEL
60 70 80 90 100
QTNITVVGCG GAGSNTVDRM ATEGIHGADL VAANTDVQHL VDIEADTKIL
110 120 130 140 150
MGQQKTKGRG AGSLPQVGEE AAIESQGEIR DSIAGSDMVF VTAGLGGGTG
160 170 180 190 200
TGSAPVVAKA AREQGALTIA IVTTPFTAEG EVRRTNAEAG LERLRDVADT
210 220 230 240 250
VIVVPNDRLL DSVGKLPVRE AFKVSDEVLM RSVKGITELI TKPGLVNLDF
260 270 280 290 300
ADVRTVMEKG GVAMIGLGEA DSDAKAADSV QSALRSPLLD VDISSANSAL
310 320 330 340 350
VNVTGGPGMS IEEAEGVVEQ LYDRIDPDAR IIWGTSIDEQ IQEEMRTMVV
360 370 380 390
VTGVDSPQIY GRNEAAEGDG PAQESTPEPE PEPQAGSEIE DIDYVE
Length:396
Mass (Da):41,188
Last modified:March 1, 2001 - v1
Checksum:i12ED06BA9C5FE68A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004437 Genomic DNA Translation: AAG18937.1
PIRiE84196
RefSeqiWP_010902232.1, NC_002607.1

Genome annotation databases

EnsemblBacteriaiAAG18937; AAG18937; VNG_0376G
GeneIDi5954295
KEGGihal:VNG_0376G
PATRICifig|64091.14.peg.280

Similar proteinsi

Entry informationi

Entry nameiFTSZ1_HALSA
AccessioniPrimary (citable) accession number: Q9HS71
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 14, 2011
Last sequence update: March 1, 2001
Last modified: May 23, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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