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Protein

Cell division protein FtsZ 1

Gene

ftsZ1

Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei179 – 1791GTPUniRule annotation
Binding sitei183 – 1831GTPUniRule annotation
Binding sitei226 – 2261GTPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi61 – 655GTPUniRule annotation
Nucleotide bindingi148 – 1503GTPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division, Septation

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZ 1UniRule annotation
Gene namesi
Name:ftsZ1UniRule annotation
Ordered Locus Names:VNG_0376G
OrganismiHalobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Taxonomic identifieri64091 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalobacterium
Proteomesi
  • UP000000554 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

  • Note: Assembles at midcell at the inner surface of the cytoplasmic membrane.UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 396396Cell division protein FtsZ 1PRO_0000414239Add
BLAST

Proteomic databases

PaxDbiQ9HS71.

Interactioni

Subunit structurei

Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.UniRule annotation

Protein-protein interaction databases

STRINGi64091.VNG0376G.

Structurei

3D structure databases

ProteinModelPortaliQ9HS71.
SMRiQ9HS71. Positions 39-364.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG02201. Archaea.
COG0206. LUCA.
InParanoidiQ9HS71.
KOiK03531.
OMAiNNAREEL.
PhylomeDBiQ9HS71.

Family and domain databases

Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ.
InterProiIPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PfamiPF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
[Graphical view]
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiSM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
[Graphical view]
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiPS01134. FTSZ_1. 1 hit.
PS01135. FTSZ_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9HS71-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSIVQDAID EAEESEDSAS EPADVAGGGG DTVPTGTMTD NELEDVLQEL
60 70 80 90 100
QTNITVVGCG GAGSNTVDRM ATEGIHGADL VAANTDVQHL VDIEADTKIL
110 120 130 140 150
MGQQKTKGRG AGSLPQVGEE AAIESQGEIR DSIAGSDMVF VTAGLGGGTG
160 170 180 190 200
TGSAPVVAKA AREQGALTIA IVTTPFTAEG EVRRTNAEAG LERLRDVADT
210 220 230 240 250
VIVVPNDRLL DSVGKLPVRE AFKVSDEVLM RSVKGITELI TKPGLVNLDF
260 270 280 290 300
ADVRTVMEKG GVAMIGLGEA DSDAKAADSV QSALRSPLLD VDISSANSAL
310 320 330 340 350
VNVTGGPGMS IEEAEGVVEQ LYDRIDPDAR IIWGTSIDEQ IQEEMRTMVV
360 370 380 390
VTGVDSPQIY GRNEAAEGDG PAQESTPEPE PEPQAGSEIE DIDYVE
Length:396
Mass (Da):41,188
Last modified:March 1, 2001 - v1
Checksum:i12ED06BA9C5FE68A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004437 Genomic DNA. Translation: AAG18937.1.
PIRiE84196.
RefSeqiWP_010902232.1. NC_002607.1.

Genome annotation databases

EnsemblBacteriaiAAG18937; AAG18937; VNG_0376G.
GeneIDi5954295.
KEGGihal:VNG0376G.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004437 Genomic DNA. Translation: AAG18937.1.
PIRiE84196.
RefSeqiWP_010902232.1. NC_002607.1.

3D structure databases

ProteinModelPortaliQ9HS71.
SMRiQ9HS71. Positions 39-364.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi64091.VNG0376G.

Proteomic databases

PaxDbiQ9HS71.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG18937; AAG18937; VNG_0376G.
GeneIDi5954295.
KEGGihal:VNG0376G.

Phylogenomic databases

eggNOGiarCOG02201. Archaea.
COG0206. LUCA.
InParanoidiQ9HS71.
KOiK03531.
OMAiNNAREEL.
PhylomeDBiQ9HS71.

Family and domain databases

Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ.
InterProiIPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PfamiPF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
[Graphical view]
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiSM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
[Graphical view]
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiPS01134. FTSZ_1. 1 hit.
PS01135. FTSZ_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700922 / JCM 11081 / NRC-1.

Entry informationi

Entry nameiFTSZ1_HALSA
AccessioniPrimary (citable) accession number: Q9HS71
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 14, 2011
Last sequence update: March 1, 2001
Last modified: July 6, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.