Q9HRP7 (RNP4_HALSA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribonuclease P protein component 4
Short name=RNase P component 4
EC=3.1.26.5

Gene names

Name:	rnp4
Ordered Locus Names:	VNG_0599C

Organism

Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium) [Reference proteome] [HAMAP]

Taxonomic identifier

64091 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Halobacterium › Halobacterium salinarum

Protein attributes

Sequence length	93 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP-Rule MF_00757
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00757
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 4 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Molecular_function	ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 93	93	Ribonuclease P protein component 4 HAMAP-Rule MF_00757		PRO_0000153850

Sequences

	Sequence		Length	Mass (Da)
	Q9HRP7 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 8EA7DBF0F02A86B5	FASTA	93	10,469
	10 20 30 40 50 60 MASIAAERID RLHTLARAAA RTGDDDRARE YVRLARRLAE RNRLTLPPAF RRFTCDDCDA 70 80 90 VLVPGRNARV RTRSGHVVVT CDCGTHARYP YTG

References

[1]

"Genome sequence of Halobacterium species NRC-1." Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D., Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D., Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K. , Cruz R., Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P., Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M., Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J., Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L., DasSarma S. Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700922 / JCM 11081 / NRC-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE004437 Genomic DNA. Translation: AAG19111.1.
PIR	C84218.
RefSeq	NP_279631.1. NC_002607.1.
3D structure databases
ProteinModelPortal	Q9HRP7.
ModBase	Search...
Protein-protein interaction databases
STRING	64091.VNG0599C.
Proteomic databases
PaxDb	Q9HRP7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAG19111; AAG19111; VNG_0599C.
GeneID	1447415.
KEGG	hal:VNG0599C.
Phylogenomic databases
eggNOG	COG2023.
KO	K03540.
OMA	PRKWKRR.
ProtClustDB	CLSK511151.
Family and domain databases
HAMAP	MF_00757. RNase_P_4.
InterPro	IPR016432. RNase_P_comp-4. IPR007175. Rpr2. [Graphical view]
Pfam	PF04032. Rpr2. 1 hit. [Graphical view]
PIRSF	PIRSF004878. RNase_P_4. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RNP4_HALSA

Accession

Primary (citable) accession number: Q9HRP7

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 5, 2004
Last sequence update:	March 1, 2001
Last modified:	May 1, 2013
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program