ID   Q9HR88_HALSA            Unreviewed;       790 AA.
AC   Q9HR88;
DT   01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2001, sequence version 1.
DT   27-MAR-2024, entry version 108.
DE   SubName: Full=Htr18 transducer {ECO:0000313|EMBL:AAG19270.1};
GN   Name=htr18 {ECO:0000313|EMBL:AAG19270.1};
GN   OrderedLocusNames=VNG_0812G {ECO:0000313|EMBL:AAG19270.1};
OS   Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS   (Halobacterium halobium).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halobacteriaceae; Halobacterium; Halobacterium salinarum NRC-34001.
OX   NCBI_TaxID=64091 {ECO:0000313|EMBL:AAG19270.1, ECO:0000313|Proteomes:UP000000554};
RN   [1] {ECO:0000313|EMBL:AAG19270.1, ECO:0000313|Proteomes:UP000000554}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700922 / JCM 11081 / NRC-1
RC   {ECO:0000313|Proteomes:UP000000554};
RX   PubMed=11016950; DOI=10.1073/pnas.190337797;
RA   Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA   Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA   Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA   Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA   Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA   Spudich J.L., Jung K.W., Alam M., Freitas T., Hou S., Daniels C.J.,
RA   Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA   DasSarma S.;
RT   "Genome sequence of Halobacterium species NRC-1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; AE004437; AAG19270.1; -; Genomic_DNA.
DR   PIR; B84238; B84238.
DR   AlphaFoldDB; Q9HR88; -.
DR   STRING; 64091.VNG_0812G; -.
DR   PaxDb; 64091-VNG_0812G; -.
DR   KEGG; hal:VNG_0812G; -.
DR   PATRIC; fig|64091.14.peg.623; -.
DR   HOGENOM; CLU_000445_107_19_2; -.
DR   InParanoid; Q9HR88; -.
DR   Proteomes; UP000000554; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   Gene3D; 6.10.250.1910; -; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF00672; HAMP; 2.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 2.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF158472; HAMP domain-like; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000554};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}.
FT   DOMAIN          277..330
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          397..450
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          469..705
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   REGION          373..399
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          764..790
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        375..393
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   790 AA;  84320 MW;  6227D876B5A35B85 CRC64;
     MLVLVGVGVF TTQAVSTQVT EQRDTELLTS TEQEAEALEE WIGRQRSATQ YLSQDNAIQS
     APQADKSEVL STRISGLTET AAALHYVNLS TDTIRASTDA AVEGDTYTSY SIPWRGEGLS
     FYGGGDVITS SVFNYRGTPV MAFASKQPGS DNAVFVFHSV ETRGEAFSRN IDGSYTQVVD
     IEGTVQIAAD ESAISSAYGA GRDAPVIATG LTTNSGIETR DGLLVGHAKV EGTDWVLLKH
     APTSNAYALE GDVQRNIVVL IVTAVAGLGA LVLVIGRDAL TALTDMSDRA EAIAAGDIDT
     AIEETTRIDE VGDLRRSFRD IQEYLQTVAG QADALAEQDF DADALDKSVP GRLGESLETM
     HWDLETAIAD LEDAQETAEQ SRKEAEQSRE EAEALAAALE SQAQDIRETV EHAADGDLTQ
     RLETDTDHES MAAIATALNS LLEELEGTIH RIQRFSKDVA ESSDHITTSA EEVKRASGQV
     SESVQEMSAD ARQQNGIVQD VSDEMTDLSA TIEEIASSSD EVAAKSNDAV SVGQSGRARS
     QDAIEEMNAV DEQAKRTIAE MEALDDEMTE IGEIVTLIDD IAEQTSMLAL NASIEAARAG
     EAGEGFAVVA DEIKSLSKET TEATQEIESL IADVQDSTTD AVTDMQEMGD RLSEGKSTVT
     DTVETIDTIV ERIEEANGGV QTINTATDEQ ATTTEEVVTM VDEVGSISDD TTARAEDAAA
     AAEEQTASLT EVTNRIQDLS DQSTDLYELL SDFTVREDHA VADGGAENTT GAFVRSASTD
     HSRDATHHDT
//