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Protein

Putative dimethyl sulfoxide reductase iron-sulfur subunit B

Gene

dmsB

Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Dimethyl sulfoxide (DMSO) reductase catalyzes the reduction of dimethyl sulfoxide (DMSO) to dimethyl sulfide (DMS) during anaerobic respiration; it can also use trimethylamine N-oxide (TMAO) as terminal electron acceptor. Subunit B is proposed to be involved in electron transfer.

Cofactori

[4Fe-4S] clusterBy similarityNote: Binds 4 [4Fe-4S] clusters.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi13 – 131Iron-sulfur 1 (4Fe-4S)By similarity
Metal bindingi16 – 161Iron-sulfur 1 (4Fe-4S)By similarity
Metal bindingi19 – 191Iron-sulfur 1 (4Fe-4S)By similarity
Metal bindingi23 – 231Iron-sulfur 2 (4Fe-4S)By similarity
Metal bindingi71 – 711Iron-sulfur 3 (4Fe-4S)By similarity
Metal bindingi74 – 741Iron-sulfur 3 (4Fe-4S)By similarity
Metal bindingi79 – 791Iron-sulfur 3 (4Fe-4S)By similarity
Metal bindingi83 – 831Iron-sulfur 4 (4Fe-4S)By similarity
Metal bindingi103 – 1031Iron-sulfur 4 (4Fe-4S)By similarity
Metal bindingi106 – 1061Iron-sulfur 4 (4Fe-4S)By similarity
Metal bindingi109 – 1091Iron-sulfur 4 (4Fe-4S)By similarity
Metal bindingi113 – 1131Iron-sulfur 3 (4Fe-4S)By similarity
Metal bindingi147 – 1471Iron-sulfur 2 (4Fe-4S)By similarity
Metal bindingi150 – 1501Iron-sulfur 2 (4Fe-4S)By similarity
Metal bindingi162 – 1621Iron-sulfur 2 (4Fe-4S)By similarity
Metal bindingi166 – 1661Iron-sulfur 1 (4Fe-4S)By similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

4Fe-4S, Iron, Iron-sulfur, Metal-binding

Protein family/group databases

TCDBi5.A.3.3.3. the prokaryotic molybdopterin-containing oxidoreductase (pmo) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative dimethyl sulfoxide reductase iron-sulfur subunit B
Short name:
DMSO reductase subunit B
Gene namesi
Name:dmsB
Synonyms:hmoA
Ordered Locus Names:VNG_0830G
OrganismiHalobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Taxonomic identifieri64091 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalobacterium
Proteomesi
  • UP000000554 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 262262Putative dimethyl sulfoxide reductase iron-sulfur subunit BPRO_0000428977Add
BLAST

Proteomic databases

PaxDbiQ9HR73.

Expressioni

Inductioni

By anaerobic conditions. Its expression is under the control of DmsR.1 Publication

Interactioni

Subunit structurei

Probable multiprotein complex that likely consists of DmsA, DmsB and DmsC.

Protein-protein interaction databases

STRINGi64091.VNG0830G.

Structurei

3D structure databases

ProteinModelPortaliQ9HR73.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 34314Fe-4S ferredoxin-type 1PROSITE-ProRule annotationAdd
BLAST
Domaini62 – 93324Fe-4S ferredoxin-type 2PROSITE-ProRule annotationAdd
BLAST
Domaini94 – 123304Fe-4S ferredoxin-type 3PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 3 4Fe-4S ferredoxin-type domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiarCOG01500. Archaea.
COG0437. LUCA.
InParanoidiQ9HR73.
KOiK00184.
OMAiFGWGTAY.
PhylomeDBiQ9HR73.

Family and domain databases

InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
[Graphical view]
PfamiPF13247. Fer4_11. 2 hits.
[Graphical view]
PROSITEiPS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9HR73-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTNYGLVIDQ ERCIGCQSCS LTCKQENNVP MGQFWNRVLT QGGDHVDTPS
60 70 80 90 100
GDYPEGGDGG TLEMTYQPTA CQHCENAPCV KVCPVNATYT RDDGIVEIDY
110 120 130 140 150
DKCMGCRYCM AACPYNARVF NWDEPEHRPE DGTGDVAERP QGVVEKCTFC
160 170 180 190 200
SHRVEDGLDP ACVVNCPADA RIFGDLDDDD STVSKYIAEY DTHQLLDEKG
210 220 230 240 250
TDPSTYYING EMSPGRPWKS KKLESELDDD EAAKAARRRS GSVENGYDVT
260
PHVPAETAGG DD
Length:262
Mass (Da):28,824
Last modified:March 1, 2001 - v1
Checksum:iB0F6C9C959FBC1BC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004437 Genomic DNA. Translation: AAG19285.1.
PIRiA84240.
RefSeqiWP_010902581.1. NC_002607.1.

Genome annotation databases

EnsemblBacteriaiAAG19285; AAG19285; VNG_0830G.
GeneIDi5953698.
KEGGihal:VNG0830G.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004437 Genomic DNA. Translation: AAG19285.1.
PIRiA84240.
RefSeqiWP_010902581.1. NC_002607.1.

3D structure databases

ProteinModelPortaliQ9HR73.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi64091.VNG0830G.

Protein family/group databases

TCDBi5.A.3.3.3. the prokaryotic molybdopterin-containing oxidoreductase (pmo) family.

Proteomic databases

PaxDbiQ9HR73.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG19285; AAG19285; VNG_0830G.
GeneIDi5953698.
KEGGihal:VNG0830G.

Phylogenomic databases

eggNOGiarCOG01500. Archaea.
COG0437. LUCA.
InParanoidiQ9HR73.
KOiK00184.
OMAiFGWGTAY.
PhylomeDBiQ9HR73.

Family and domain databases

InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
[Graphical view]
PfamiPF13247. Fer4_11. 2 hits.
[Graphical view]
PROSITEiPS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700922 / JCM 11081 / NRC-1.
  2. "Genomic analysis of anaerobic respiration in the archaeon Halobacterium sp. strain NRC-1: dimethyl sulfoxide and trimethylamine N-oxide as terminal electron acceptors."
    Muller J.A., DasSarma S.
    J. Bacteriol. 187:1659-1667(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: PUTATIVE FUNCTION, INDUCTION.
    Strain: ATCC 700922 / JCM 11081 / NRC-1.

Entry informationi

Entry nameiDMSB_HALSA
AccessioniPrimary (citable) accession number: Q9HR73
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 14, 2014
Last sequence update: March 1, 2001
Last modified: June 8, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.