Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. Glyceraldehyde-3-phosphate dehydrogenase (gap)
  2. Phosphoglycerate kinase (pgk)
  3. 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (gpmI)
  4. Enolase (eno)
  5. Pyruvate kinase (pykA)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei37SubstrateUniRule annotation1
Binding sitei117SubstrateUniRule annotation1
Binding sitei157SubstrateUniRule annotation1
Binding sitei332ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi357 – 360ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processGlycolysis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:VNG_1216G
OrganismiHalobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Taxonomic identifieri64091 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalobacterium
Proteomesi
  • UP000000554 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001460521 – 398Phosphoglycerate kinaseAdd BLAST398

Proteomic databases

PaxDbiQ9HQD1
PRIDEiQ9HQD1

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi64091.VNG1216G

Structurei

3D structure databases

ProteinModelPortaliQ9HQD1
SMRiQ9HQD1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni21 – 23Substrate bindingUniRule annotation3
Regioni60 – 63Substrate bindingUniRule annotation4

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00496 Archaea
COG0126 LUCA
InParanoidiQ9HQD1
KOiK00927
OMAiDMIFDIG
OrthoDBiPOG093Z051V
PhylomeDBiQ9HQD1

Family and domain databases

Gene3Di3.40.50.12603 hits
HAMAPiMF_00145 Phosphoglyc_kinase, 1 hit
InterProiView protein in InterPro
IPR001576 Phosphoglycerate_kinase
IPR015824 Phosphoglycerate_kinase_N
IPR036043 Phosphoglycerate_kinase_sf
PANTHERiPTHR11406 PTHR11406, 1 hit
PfamiView protein in Pfam
PF00162 PGK, 1 hit
PIRSFiPIRSF000724 Pgk, 1 hit
PRINTSiPR00477 PHGLYCKINASE
SUPFAMiSSF53748 SSF53748, 1 hit

Sequencei

Sequence statusi: Complete.

Q9HQD1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAIRTLDDLA AANRAIGVRV DINSPLTAAG GLADDARLRA HVDTLAELLA
60 70 80 90 100
ADARVAVLAH QGRPGGDEFA RLERHADRLD ALLDAPVSYC DATFSTGARD
110 120 130 140 150
AVADLAPGEA VVLENTRFYS EEYMAFAPER AADTALVDGL APALDAYVND
160 170 180 190 200
AFAAAHRSQP SLVGFPEVLP SYAGRVMEAE LDALSGVADT PTPRTYVVGG
210 220 230 240 250
AKVPDSVEVA AHALSHGLAD NVLVTGVVAN VFLAATGVDL GRASTDFIHE
260 270 280 290 300
RDYGTEIARA ADLLAAHNDA LHLPVDVAVE RDGARCELST DALPPAGDEA
310 320 330 340 350
VCDIGSDTVD AYADVLADSE TVVVNGPAGV FEDDLFADGT RGVFDAASEV
360 370 380 390
EHSIVGGGDT AAAIRRFDIT GFDHVSTGGG AAINLLTDAD LPAVAALR
Length:398
Mass (Da):41,046
Last modified:March 1, 2001 - v1
Checksum:i90CC881964915547
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004437 Genomic DNA Translation: AAG19584.1
PIRiD84277
RefSeqiWP_010902880.1, NC_002607.1

Genome annotation databases

EnsemblBacteriaiAAG19584; AAG19584; VNG_1216G
GeneIDi5952870
KEGGihal:VNG_1216G
PATRICifig|64091.14.peg.932

Similar proteinsi

Entry informationi

Entry nameiPGK_HALSA
AccessioniPrimary (citable) accession number: Q9HQD1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 27, 2002
Last sequence update: March 1, 2001
Last modified: February 28, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome